Swipe om te navigeren naar een ander artikel
To identify possible early signs of autism spectrum disorder (ASD) within the Danish National Birth Cohort, we studied prospectively collected interviews from 76,441 mothers about their children’s development and behaviour at 6 and 18 months. In Danish national registries, 720 children with ASD and 231 children with intellectual disability (ID) were identified. At 6 months, associations between early signs and ASD or ID were found only in few areas. At 18 months social, language, and motor skills were delayed, and suspicion of vision and hearing problems were increased for both groups. Signs distinguishing ASD from ID were unclear, and the positive predictive values regarding ASD were below 10 % for individual predictors and aggregated risk scores.
Log in om toegang te krijgen
Met onderstaand(e) abonnement(en) heeft u direct toegang:
DNBC. (2012). Danish National Birth Cohort. Retrieved from http://www.ssi.dk/English/RandD/Research%20areas/Epidemiology/DNBC/For%20researchers/Data%20available.aspx. Accessed 28 Jan 2013.
Kalbfleisch, J. D., & Prentice, R. L. (2002). The statistical analysis of failure time data (2nd ed.). New York: Wiley. CrossRef
Kirkwood, B., & Sterne, J. (2003). Essential medical statistics (2nd ed.). Oxford: Blackwell Science.
Lloyd, M., Macdonald, M., & Lord, C. (2011). Motor skills of toddlers with autism spectrum disorders. Autism. doi: 10.1177/1362361311402230.
Ozonoff, S., Iosif, A. M., Baguio, F., Cook, I. C., Hill, M. M., Hutman, T., et al. (2010). A prospective study of the emergence of early behavioral signs of autism. Journal of the American Academy of Child and Adolescent Psychiatry, 49, 256–266. PubMed
Pedersen, C. B., Gotzsche, H., Moller, J. O., & Mortensen, P. B. (2006). The Danish Civil Registration System. A cohort of eight million persons. Danish Medical Bulletin, 53, 441–449. PubMed
Vostanis, P., Smith, B., Corbett, J., Sungum-Paliwal, R., Edwards, A., Gingell, K., et al. (1998). Parental concerns of early development in children with autism and related disorders. Autism: International journal of research, 2, 229–242. CrossRef
Yeargin-Allsopp, M., Rice, C., Karapurkar, T., Doernberg, N., Boyle, C., & Murphy, C. (2003). Prevalence of autism in a US metropolitan area. The journal of the American Medical Association, 289, 49–55. CrossRef
- Early Signs of Autism in Toddlers: A Follow-Up Study in the Danish National Birth Cohort
Erik T. Parner
Marlene B. Lauritsen
- Springer US