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05-05-2017 | Original Paper | Uitgave 8/2017

Dose-Response Effects of Long-Acting Liquid Methylphenidate in Children with Attention Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD): A Pilot Study

Tijdschrift:: Journal of Autism and Developmental Disorders > Uitgave 8/2017

Auteurs:: Soo-Jeong Kim, Sophia Shonka, William P. French, Jennifer Strickland, Lindsey Miller, Mark A. Stein

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Abstract

Attention deficit/hyperactivity disorder (ADHD) symptoms are common in youth with autism spectrum disorders (ASD) and are frequently treated with stimulant medications. Twenty-seven children were randomized to different dose titration schedules, and ADHD symptoms, tolerability, and aberrant behaviors were assessed weekly during a 6-week trial with long-acting liquid methylphenidate (MPH). MPH at low to moderate doses was effective in reducing ADHD symptoms and was well tolerated in young children with ASD and ADHD. Future studies are needed to assess generalization and maintenance of efficacy.

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Titel: Dose-Response Effects of Long-Acting Liquid Methylphenidate in Children with Attention Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD): A Pilot Study
Auteurs:: Soo-Jeong Kim
Sophia Shonka
William P. French
Jennifer Strickland
Lindsey Miller
Mark A. Stein
Publicatiedatum: 05-05-2017
DOI: https://doi.org/10.1007/s10803-017-3125-1
Uitgeverij: Springer US
Tijdschrift: Journal of Autism and Developmental Disorders
Uitgave 8/2017
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432

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Dose-Response Effects of Long-Acting Liquid Methylphenidate in Children with Attention Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD): A Pilot Study

Abstract

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