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Gepubliceerd in: Journal of Abnormal Child Psychology 7/2014

01-10-2014

Do Childhood Externalizing Disorders Predict Adult Depression? A Meta-Analysis

Auteurs: Annemarie K. Loth, Deborah A. G. Drabick, Ellen Leibenluft, Leslie A. Hulvershorn

Gepubliceerd in: Research on Child and Adolescent Psychopathology | Uitgave 7/2014

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Abstract

Childhood externalizing disorders have been linked to adult affective disorders, although some studies fail to substantiate this finding. Multiple longitudinal cohort studies identifying childhood psychopathology and their association with adult psychiatric illness have been published. To examine the association between childhood externalizing symptoms or disorders and the development of adult depression across cohorts, a meta-analysis was performed. Potential studies were identified using a PubMed search through November 2013. All published, prospective, longitudinal, community-sampled cohort studies of children (≤ 13 years) with externalizing symptoms or disorders (aggression, conduct problems, oppositional defiant disorder, conduct disorder), reassessed in adulthood (≥ 18 years) for depressive disorders (major depressive disorder, depressive disorder NOS, or dysthymic disorder) were included. A random effects model was used to summarize the pooled effect sizes. Ancillary analyses considered covariates that could account for variance among studies. Ten studies representing eight cohorts of children initially assessed at age 13 or younger (N = 17,712) were included in the meta-analysis. Childhood externalizing behavior was associated with adult depressive disorders (OR = 1.52, 95 % confidence interval = 1.27–1.80, p < 0.0001). Utilizing Orwin’s Fail-safe N approach, 263 studies with a mean odds ratio of 1.0 would have to be added to the analysis before the cumulative effect would become trivial. Externalizing psychopathology in childhood is associated with the development of unipolar depressive disorders in adulthood.
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Metagegevens
Titel
Do Childhood Externalizing Disorders Predict Adult Depression? A Meta-Analysis
Auteurs
Annemarie K. Loth
Deborah A. G. Drabick
Ellen Leibenluft
Leslie A. Hulvershorn
Publicatiedatum
01-10-2014
Uitgeverij
Springer US
Gepubliceerd in
Research on Child and Adolescent Psychopathology / Uitgave 7/2014
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI
https://doi.org/10.1007/s10802-014-9867-8