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Gepubliceerd in:

02-02-2017

Discrimination and the HPA axis: current evidence and future directions

Auteurs: David Busse, Ilona S. Yim, Belinda Campos, Christopher K. Marshburn

Gepubliceerd in: Journal of Behavioral Medicine | Uitgave 4/2017

Abstract

Numerous studies suggest that discrimination is associated with poor physical and mental health outcomes. Whereas the cardiovascular system has been extensively studied as a potential pathway linking discrimination with disease, the role of the hypothalamic–pituitary–adrenal (HPA) axis remains understudied. We conducted a systematic review of research on discrimination and related constructs as predictors and correlates of HPA axis activity. Twenty seven studies (10 experimental, 17 observational) met inclusion criteria. Studies suggest that discrimination is associated with alterations in HPA axis activity and that the direction of this association depends on the timing and chronicity of the discrimination experience. There is also evidence of important modulating variables (race, socioeconomic status) and contextual confounders (emotional, situational) that warrant further study. Accounting for the HPA axis in addition to the cardiovascular system will contribute to a more comprehensive understanding of the biobehavioral pathways contributing to physical and mental health inequities related to discrimination.

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Titel: Discrimination and the HPA axis: current evidence and future directions
Auteurs: David Busse
Ilona S. Yim
Belinda Campos
Christopher K. Marshburn
Publicatiedatum: 02-02-2017
Uitgeverij: Springer US
Gepubliceerd in: Journal of Behavioral Medicine / Uitgave 4/2017
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521
DOI: https://doi.org/10.1007/s10865-017-9830-6

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