Top

Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-07-2011 | Original Paper

Differential Olfactory Identification in Children with Autism and Asperger’s Disorder: A Comparative and Longitudinal Study

Auteurs: Tamara May, Warrick J. Brewer, Nicole J. Rinehart, Peter G. Enticott, Avril V. Brereton, Bruce J. Tonge

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 7/2011

Abstract

Key theories of autism implicate orbitofrontal cortex (OFC) compromise, while olfactory identification (OI) deficits are associated with OFC dysfunction. This study aimed to complete a 5-year follow-up of children with high-functioning autism (HFA) who previously lacked the normal age-OI association; and compare unirhinal-OI in children with HFA, Asperger’s disorder (ASP), and controls. While both HFA and controls had improved birhinal-OI at follow-up, reduced OI in some HFA participants suggested OFC deterioration and heterogeneous OFC development. Unirhinal-OI was impaired in HFA but not ASP relative to controls, suggesting orbitofrontal compromise in HFA but integrity in ASP. Differing IQ-OI relationships existed between HFA and ASP. Findings support the hypothesis of separate neurobiological underpinnings in ASP and HFA, specifically differential orbitofrontal functioning.

volgende artikel Feeling Good, Feeling Bad: Influences of Maternal Perceptions of the Child and Marital Adjustment on Well-being in Mothers of Children with an Autism Spectrum Disorder

Amaral, D. G., Schumann, C. M., & Nordahl, C. W. (2008). Neuroanatomy of autism. Trends in Neurosciences, 31(3), 137–145.PubMedCrossRef

American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed., Text Revision). Washington, DC: Author.CrossRef

Barnett, R., Maruff, P., Purcell, R., Wainwright, K., Kyrios, M., & Brewer, W. (1999). Impairment of olfactory identification in obsessive-compulsive disorder. Psychological Medicine, 29, 1227–1233.PubMedCrossRef

Baron-Cohen, S. (2004). The cognitive neuroscience of autism. Journal of Neurology, Neurosurgery and Psychiatry, 75, 945–948.CrossRef

Baron-Cohen, S., Leslie, A. M., & Frith, U. (1985). Does the autistic child have a “theory of mind”? Cognition, 21, 37–46.PubMedCrossRef

Baron-Cohen, S., Ring, H., Moriarty, J., Schmitz, B., Costa, D., & Ell, P. (1994). Recognition of mental state terms: Clinical findings in children with autism and a functional neuroimaging study of normal adults. British Journal of Psychiatry, 165, 640–649.PubMedCrossRef

Beaumont, R. B., & Sofronoff, K. (2008). A new computerised advanced theory of mind measure for children with Asperger Syndrome: The ATOMIC. Journal of Autism and Developmental Disorders, 38, 249–260.PubMedCrossRef

Bennetto, L., Kuschner, E. S., & Hyman, S. L. (2007). Olfaction and taste processing in autism. Biological Psychiatry, 62, 1015–1021.PubMedCrossRef

Brewer, W., Brereton, A. V., & Tonge, B. J. (2008). Dissociation of age and ability on a visual analogue of the University of Pennsylvania Smell Identification Test in children with autism. Research in Autism Spectrum Disorders, 158, 107–115.

Brewer, W. J., Pantelis, C., Anderson, V., Velakoulis, D., Singh, B., Copolov, D. L., et al. (2001). Stability of olfactory identification deficits in neuroleptic-naive patients with first-episode psychosis. American Journal of Psychiatry, 158, 107–115.PubMedCrossRef

Brewer, W. J., Pantelis, C., De Luca, C., & Wood, S. (2006). Olfactory Processing and Brain Maturation. In W. Brewer, D. Castle, & C. Pantelis (Eds.), Olfaction and the brain (pp. 103–118). Cambridge: Cambridge University Press.CrossRef

Chakrabarti, S., & Fombonne, E. (2005). Pervasive developmental disorders in preschool children: Confirmation of high prevalence. American Journal of Psychiatry, 162, 1133–1141.PubMedCrossRef

Chiron, C., Jambaque, I., Nabbout, R., Lounes, R., Syrota, A., & Dulac, O. (1997). The right brain hemisphere is dominant in human infants. Brain: A Journal of Neurology, 120, 1057–1065.

Doty, R. L. (1995). The smell identification test administration manual (3rd ed.). New Jersey: Sensonics.

Doty, R. L., Frye, R. E., & Agrawal, U. (1989). Internal consistency and short-term test-retest reliability of the University of Pennsylvania Smell Identification Test. Perception and Psychophysics, 45, 381–384.PubMedCrossRef

Doty, R. L., Shaman, P., Applebaum, S. L., Giberson, R., Siksorski, L., & Rosenberg, L. (1984a). Smell identification ability: Changes with age. Science, 226, 1441–1443.PubMedCrossRef

Doty, R. L., Shaman, P., & Dann, M. (1984b). Development of the University of Pennsylvania smell identification test: A standardized microencapsulated test of olfactory function. Physiology & Behavior, 32, 489–502.CrossRef

Girgis, R. R., Minshew, N. J., Melhem, N. M., Nutche, J. J., Keshavan, M. S., & Hardan, A. Y. (2007). Volumetric alterations of the orbitofrontal cortex in autism. Progress in Neuro Psychopharmacology & Biological Psychiatry, 31(1), 41–45.CrossRef

Gogtay, N., Giedd, J. N., Lusk, L., Hayashi, K. M., Greenstein, D., Vaituzis, A. C., et al. (2004). Dynamic mapping of human cortical development during childhood through early adulthood. Proceedings of the National Academy of Sciences of the United States of America, 101, 8174–8179.PubMedCrossRef

Good, K. P., Martzke, J. S., Daoud, M. A., & Kopala, L. C. (2003). Unirhinal Norms for the University of Pennsylvania Smell Identification Test. Clinical Neuropsychologist, 17, 226–234.PubMed

Happe, F., Ehlers, S., Fletcher, P., Frith, U., Johansson, M., Gillberg, C., et al. (1996). Theory of mind’ in the brain. Evidence from a PET scan study of Asperger syndrome. Neuroreport: An International Journal for the Rapid Communication of Research in Neuroscience, 8, 197–201.

Hardan, A. Y., Girgis, R. R., Lacerda, A. L., Yorbik, O., Kilpatrick, M., Keshavan, M. S., et al. (2006). Magnetic resonance imaging study of the orbitofrontal cortex in Autism. Journal of Child Neurology, 21, 866–871.PubMedCrossRef

Johnson, S. A., Yechiam, E., Murphy, R. R., Queller, S., & Stout, J. C. (2006). Motivational processes and autonomic responsivity in Asperger’s disorder: Evidence from the Iowa Gambling Task. Journal of the International Neuropsychological Society, 12, 668–676.PubMed

Kaland, N., Callesen, K., Moller-Nielsen, A., Mortensen, E. L., & Smith, L. (2008). Performance of children and adolescents with Asperger syndrome or high-functioning autism on advanced theory of mind tasks. Journal of Autism and Developmental Disorders, 38, 1112–1123.PubMedCrossRef

Karsz, F., Vance, A., Anderson, V., Brann, P., Wood, S., Pantelis, C., et al. (2008). Olfactory impariments in child attention-deficity/hyperactivity disorder. Journa of Clinical Psychiatry, 69, 1462–1468.CrossRef

Kopala, L. C., Good, K. P., Koczapski, A. B., & Honer, W. G. (1998). Olfactory deficits in patients with schizophrenia and severe polydipsia. Biological Psychiatry, 43, 497–502.PubMedCrossRef

Lawrence, N. S., Jollant, F., O’Daly, O., Zelaya, F., & Phillips, M. L. (2009). Distinct roles of prefrontal cortical subregions in the Iowa Gambling Task. Cerebral Cortex, 19, 1134–1143.PubMedCrossRef

Lord, C., Risi, S., Lambrecht, L., Cook, E.H., Leventhal, B.L., DiLavore, P.C., et al. (2000). The Autism Diagnostic Observation Schedule-Generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205–223.PubMedCrossRef

Lord, C., Rutter, M., & La Couteur, A. (1994). Autism diagnostic interview–revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasie developmental disorders. Journal of Autism and Developmental Disorders, 24, 659–685.PubMedCrossRef

Lotspeich, L., Kwon, H., Schumann, C. M., Fryer, S. L., Goodlin-Jones, B. L., Buonocore, M. H., et al. (2004). Investigation of neuroanatomical differences between autism and asperger syndrome. Archives of General Psychiatry, 61, 291–298.PubMedCrossRef

Mackay-Sim, A., & Doty, R. L. (2001). The University of Pennsylvania smell identification test: Normative adjustment for Australian subjects. Australian Journal of Oto-Laryngology, 4(3), 174–177.

Martzke, J. S., Kopala, L. C., & Good, K. P. (1997). Olfactory dysfunction in neuropsychiatric disorders: Review and methodological considerations. Biological Psychiatry, 42, 721–732.PubMedCrossRef

McAlonan, G. M., Cheung, C., Cheung, V., Wong, N., Suckling, J., & Chua, S. E. (2009). Differential effects on white-matter systems in high-functioning autism and Asperger’s syndrome. Psychological Medicine, 39, 1885–1893.PubMedCrossRef

McAlonan, G. M., Suckling, J., Wong, N., Cheung, V., Lienenkaemper, N., Cheung, C., et al. (2008). Distinct patterns of grey matter abnormality in high-functioning autism and Asperger’s syndrome. Journal of Child Psychology and Psychiatry, 49, 1287–1295.PubMedCrossRef

Miller, G. M., & Chapman, J. P. (2001). Misunderstanding analysis of covariance. Journal of Abnormal Psychology, 110, 40–48.PubMedCrossRef

Minshew, N. J., & Williams, D. L. (2007). The new neurobiology of autism. Archives of Neurology, 64, 945–950.PubMedCrossRef

Mullins, M., & Rincover, A. (1985). Comparing autistic and normal children along the dimensions of reinforcement maximization, stimulus sampling, and responsiveness to extinction. Journal of Experimental Child Psychology, 40, 350–374.PubMedCrossRef

Ozonoff, S., Pennington, B. F., & Rogers, S. J. (1991a). Executive function deficits in high-functioning autistic individuals: Relationship to theory of mind. Journal of Child Psychology and Psychiatry, 32, 1081–1105.PubMedCrossRef

Ozonoff, S., Rogers, S. J., & Pennington, B. F. (1991b). Asperger’s syndrome: Evidence of an empirical distinction from high-functioning autism. Journal of Child Psychology and Psychiatry, 32, 1107–1122.PubMedCrossRef

Peterson, C. C., Slaughter, V. P., & Paynter, J. (2007). Social maturity and theory of mind in typically developing children and those on the autism spectrum. Journal of Child Psychology and Psychiatry, 48, 1243–1250.PubMedCrossRef

Potter, H., & Butters, N. (1980). An assessment of olfactory deficits in patients with damage to prefrontal cortex. Neuropsychologia, 18, 621–628.PubMedCrossRef

Qureshy, A., Kawashima, R., Imran, M. B., Sugiura, M., Goto, R., Okada, K., et al. (2000). Functional mapping of human brain in olfactory processing: A PET study. Journal of Neurophysiology, 84, 1656–1666.PubMed

Rinehart, N. J., Bradshaw, J. L., Brereton, A. V., & Tonge, B. J. (2002a). A clinical and neurobehavioural review of high-functioning autism and Asperger’s disorder. Australian and New Zealand Journal of Psychiatry, 36, 762–770.PubMedCrossRef

Rinehart, N. J., Bradshaw, J. L., Brereton, A. V., & Tonge, B. J. (2002b). Lateralization in individuals with high-functioning autism and Asperger’s disorder: A frontostriatal model. Journal of Autism and Developmental Disorders, 32, 321–332.PubMedCrossRef

Rinehart, N. J., Bradshaw, J. L., Tonge, B. J., Brereton, A. V., & Bellgrove, M. A. (2002c). A neurobehavioral examination of individuals with high-functioning autism and Asperger disorder using a fronto-striatal model of dysfunction. Behavioral and Cognitive Neuroscience Reviews, 1, 164–177.PubMed

Rinehart, N. J., Tonge, B. J., Bradshaw, J. L., Iansek, R., Enticott, P. G., & Johnson, K. A. (2006). Movement-related potentials in high-functioning autism and Asperger’s disorder. Developmental Medicine and Child Neurology, 48, 272–277.PubMedCrossRef

Russell, J. (1997). Autism as an executive disorder. New York: Oxford University Press.

Savage, R., Combs, D. R., Pinkston, J. B., Advokat, C., & Gouvier, W. (2002). The role of temporal lobe and orbitofrontal cortices in olfactory memory function. Archives of Clinical Neuropsychology, 17, 305–318.PubMed

Schopler, E. (1996). Are autism and Asperger Syndrome different labels or different disabilities. Journal of Autism and Developmental Disorders, 26, 109–110.PubMedCrossRef

Schopler, E., Lansing, M. D., Reichler, R. J., & Marcus, L. M. (2004). Psychoeducational Profile Third Edition (PEP-3). Pro-Ed, USA.

Schopler, E., Reichler, R. J., Bashford, A., Lansing, M. D., & Marcus, L. M. (1990). Individualized assessment and treatment for autistic and developmental disabled children: Psychoeducational profile revised (PEP-R). Austin, TX: Proed.

Schopler, E., Reichler, R. J., & Renner, B. R. (1988). The childhood autism rating scale (CARS). Los Angeles: Western Psychological Services.

Suzuki, Y., Critchley, H. D., Rowe, A., Howlin, P., & Murphy, D. G. M. (2003). Impaired olfactory identification in Asperger’s syndrome. Journal of Neuropsychiatry and Clinical Neurosciences, 15, 105–107.PubMedCrossRef

Suzuki, Y., Critchley, H. D., Suckling, J., Fukuda, R., Williams, S. C., Andrew, C., et al. (2001). Functional magnetic resonance imaging of odor identification: The effect of aging. Journals of Gerontology Series A-Biological Sciences & Medical Sciences, 56, 756–760.

Tager-Flusberg, H. (2008). Cognitive neuroscience of autism. Journal of the International Neuropsychological Society, 14, 917–921.PubMedCrossRef

Tonge, B. J., Brereton, A. V., Gray, K. M., & Einfeld, S. L. (1999). Behavioural and emotional disturbance in high-functioning autism and Asperger syndrome. Autism, 3, 117–130.CrossRef

Vasterling, J. J., Brailey, K., & Sutker, P. B. (2000). Olfactory identification in combat-related posttraumatic stress disorder. Journal of Traumatic Stress, 13, 241–253.PubMedCrossRef

Vollm, B. A., Taylor, A. N., Richardson, P., Corcoran, R., Stirling, J., McKie, S., et al. (2006). Neuronal correlates of theory of mind and empathy: A functional magnetic resonance imaging study in a nonverbal task. NeroImage, 29, 90–98.CrossRef

Wechsler, D. (1989). Wechsler pre school and primary scale of intelligence-revised. San Antonio: The Psychological Corporation.

Wechsler, D. (1991). Manual for the wechsler intelligence scale for children (3rd ed.). San Antonio, TX: Psychological Corporation.

Wechsler, D. (2003). Wechsler intelligence scale for children (4th ed.). San Antonio, TX: The Psychological Corporation.

Ziatas, K., Durkin, K., & Pratt, C. (1998). Belief term development in children with autism, Asperger syndrome, specific language impairment, and normal development: Links to theory of mind development. Journal of Child Psychology and Psychiatry, 39, 755–763.PubMedCrossRef

Titel: Differential Olfactory Identification in Children with Autism and Asperger’s Disorder: A Comparative and Longitudinal Study
Auteurs: Tamara May
Warrick J. Brewer
Nicole J. Rinehart
Peter G. Enticott
Avril V. Brereton
Bruce J. Tonge
Publicatiedatum: 01-07-2011
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 7/2011
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-010-1101-0

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen

Andere artikelen Uitgave 7/2011

Local Information Processing in Adults with High Functioning Autism and Asperger Syndrome: The Usefulness of Neuropsychological Tests and Self-Reports

Brief Report: Developing Spatial Frequency Biases for Face Recognition in Autism and Williams Syndrome

Picture Me Playing: Increasing Pretend Play Dialogue of Children with Autism Spectrum Disorders

Sally J. Rogers and Geraldine Dawson: Review of Early Start Denver Model for Young Children with Autism: Promoting Language, Learning and Engagement

Do High-Functioning People with Autism Spectrum Disorder Spontaneously Use Event Knowledge to Selectively Attend to and Remember Context-Relevant Aspects in Scenes?

Yale Child Study Center Autism Program