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Gepubliceerd in: Journal of Autism and Developmental Disorders 8/2022

03-08-2021 | Original Paper

Diagnostic and Physical Effects in Parasympathetic Response to Social Evaluation in Youth With and Without Autism Spectrum Disorder

Auteurs: Rachael A. Muscatello, Ahra Kim, Simon Vandekar, Blythe A. Corbett

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 8/2022

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Abstract

Individuals with autism spectrum disorder (ASD) may demonstrate atypical autonomic (ANS) responses; however, research remains inconsistent. This study examined parasympathetic response during social evaluation in 241 youth (10–13 years) with ASD (n = 138) or typical development (TD; n = 103). Diagnosis, age, pubertal development, and body mass index (BMI) were hypothesized to be associated with ANS function. Linear mixed effects models demonstrated lower RSA in ASD relative to TD in a base model with no covariates. However, when accounting for differences in BMI, there was no evidence of atypical parasympathetic regulation in youth with ASD. As lower parasympathetic regulation may increase susceptibility for a number of conditions, it will be important to elucidate the link between BMI and the ANS, especially in ASD.
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Metagegevens
Titel
Diagnostic and Physical Effects in Parasympathetic Response to Social Evaluation in Youth With and Without Autism Spectrum Disorder
Auteurs
Rachael A. Muscatello
Ahra Kim
Simon Vandekar
Blythe A. Corbett
Publicatiedatum
03-08-2021
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 8/2022
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-021-05224-0

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