Swipe om te navigeren naar een ander artikel
Laura Fusar-Poli and Natascia Brondino are joint first authors.
Diagnosing autism spectrum disorder (ASD) in adulthood often represents a challenge in clinical practice. The aim of the present study was to evaluate the sensitivity and specificity of the ADOS and ADI-R in diagnosing ASD in adults. 113 subjects with an IQ of 70 or above were assessed through an extensive clinical evaluation. The ADOS-2 Module 4 and the ADI-R were separately administered by staff members blind to clinical judgment. Our results cautiously confirm the accuracy of ADOS-2 Module 4, while suggest that ADI-R might not be reliable in adults without intellectual disability. Clinicians’ training and experience remains of primary importance while assessing adults who could potentially belong to the autism spectrum.
Log in om toegang te krijgen
Met onderstaand(e) abonnement(en) heeft u direct toegang:
American Psychiatric Association (2000). Diagnostic and statistical manual of mental disorders: DSM-IV-TR (4th edn.). Washington, DC: American Psychiatric Association.
American Psychiatric Association (2013). Diagnostic and statistical manual of mental disorders: DSM-5 (5th edn.). Washington, DC: American Psychiatric Association. CrossRef
Bent, C. A., Barbaro, J., & Dissanayake, C. (2016). Change in autism diagnoses prior to and following the introduction of DSM-5. Journal of Autism and Developmental Disorders, 47(1), 163–171. CrossRef
Centers of Disease Control and Prevention. (2014). Prevalence of autism spectrum disorder among children aged 8 years-autism and developmental disabilities monitoring network, 11 sites, United States, 2010. Morbidity and Mortality Weekly Report. Surveillance Summaries (Washington, DC: 2002), 63(2), 1.
De Bildt, A., Oosterling, I. J., van Lang, N. D. J., Kuijper, S., Dekker, V., Sytema, S., et al. (2013). How to use the ADI-R for classifying autism spectrum disorders? Psychometric properties of criteria from the literature in 1,204 Dutch children. Journal of Autism and Developmental Disorders, 43(10), 2280–2294. CrossRefPubMed
De Bildt, A., Sytema, S., Ketelaars, C., Kraijer, D., Mulder, E., Volkmar, F., et al. (2004). Interrelationship between autism diagnostic observation schedule-generic (ADOS-G), autism diagnostic interview-revised (ADI-R), and the diagnostic and statistical manual of mental disorders (DSM-IV-TR) classification in children and adolescents with mental retardation. Journal of Autism and Developmental Disorders, 34(2), 129–137. CrossRefPubMed
De Bildt, A., Sytema, S., Meffert, H., & Bastiaansen, J. A. C. J. (2015). The Autism Diagnostic Observation Schedule, Module 4: Application of the revised algorithms in an independent, well-defined, Dutch sample (n = 93). Journal of Autism and Developmental Disorders, 46(1), 21–30. CrossRefPubMedCentral
Falkmer, T., Anderson, K., Falkmer, M., & Horlin, C. (2013). Diagnostic procedures in autism spectrum disorders: A systematic literature review. European Child &. Adolescent Psychiatry, 22(6), 329–340. CrossRef
First, M. B., Gibbon, M., Spitzer, R. L., Williams, J. B. W., & Benjamin, L. S. (1997). Structured clinical interview for DSM-IV axis II personality disorders (SCID-II). Washington, DC: American Psychiatric Press, Inc.
Hosmer, D. W., & Lemeshow, S. (2004). Applied logistic regression. New York: John Wiley & Sons.
Interagency Autism Coordinating Committee (IACC). (2012). IACC strategic plan for autism spectrum disorder (ASD) research—2012 update. December 2012. Retrieved from the U.S. Department of Health and Human Services Interagency Autism Coordinating Committee website: http://iacc.hhs.gov/strategic-plan/2012/index.shtml.
Kamp-Becker, I., Ghahreman, M., Heinzel-Gutenbrunner, M., Peters, M., Remschmidt, H., & Becker, K. (2013). Evaluation of the revised algorithm of Autism Diagnostic Observation Schedule (ADOS) in the diagnostic investigation of high-functioning children and adolescents with autism spectrum disorders. Autism: The International Journal of Research and Practice, 17(1), 87–102. CrossRef
Langmann, A., Becker, J., Poustka, L., Becker, K., & Kamp-Becker, I. (2017). Diagnostic utility of the autism diagnostic observation schedule in a clinical sample of adolescents and adults. Research in Autism Spectrum Disorders, 34, 34–43. CrossRef
Lord, C., DiLavore, P. C., & Gotham, K. (2012). Autism diagnostic observation schedule. Torrance, CA: Western Psychological Services.
Mazefsky, C. A., & Oswald, D. P. (2006). The discriminative ability and diagnostic utility of the ADOS-G, ADI-R, and GARS for children in a clinical setting. Autism: The International Journal of Research and Practice, 10(6), 533–549. CrossRef
Molloy, C. A., Murray, D. S., Akers, R., Mitchell, T., & Manning-Courtney, P. (2011). Use of the Autism Diagnostic Observation Schedule (ADOS) in a clinical setting. Autism: The International Journal of Research and Practice, 15(2), 143–162. CrossRef
National Institute of Clinical Excellence (2012). Autism: Recognition, referral, diagnosis, and management of adults on the autism spectrum. Manchester: NICE Clinical Guideline.
Ozonoff, S. (2005). Evidence-based assessment of autism spectrum disorders in children and adolescents. Journal of Clinical Child & Adolescent Psychology, 34(3), 523–540. CrossRef
Papanikolaou, K., Paliokosta, E., Houliaras, G., Vgenopoulou, S., Giouroukou, E., Pehlivanidis, A., et al. (2008). Using the Autism Diagnostic Interview-Revised and the Autism Diagnostic Observation Schedule-Generic for the diagnosis of autism spectrum disorders in a Greek sample with a wide range of intellectual abilities. Journal of Autism and Developmental Disorders, 39(3), 414–420. CrossRefPubMed
Piven, J., Harper, J., Palmer, P., & Arndt, S. (1996). Course of behavioral change in autism: A retrospective study of high-IQ adolescents and adults. Journal of the American Academy of Child & Adolescent Psychiatry, 35(4), 523–529. CrossRef
Pugliese, C. E., Kenworthy, L., Bal, V. H., Wallace, G. L., Yerys, B. E., Maddox, B. B, et al. (2015). Replication and comparison of the newly proposed ADOS-2, module 4 algorithm in ASD without ID: A multi-site study. Journal of Autism and Developmental Disorders, 45(12), 3919–3931.
Raven, J. C. (1941). Standardization of progressive matrices, 1938. British Journal of Medical Psychology, 19(1), 137–150. CrossRef
Risi, S., Lord, C., Gotham, K., Corsello, C., Chrysler, C., Szatmari, P., et al. (2006). Combining information from multiple sources in the diagnosis of autism spectrum disorders. Journal of the American Academy of Child & Adolescent Psychiatry, 45(9), 1094–1103. CrossRef
Rynkiewicz, A., Schuller, B., Marchi, E., Piana, S., Camurri, A., Lassalle, A., et al. (2016). An investigation of the ‘female camouflage effect’ in autism using a computerized ADOS-2 and a test of sex/gender differences. Molecular Autism, 7(1), 1. CrossRef
Soke, G. N., Philofsky, A., Diguiseppi, C., Lezotte, D., Rogers, S., & Hepburn, S. (2011). Longitudinal changes in scores on the Autism Diagnostic Interview—Revised (ADI-R) in pre-school children with autism Implications for diagnostic classification and symptom stability. Autism: The International Journal of Research and Practice, 15(5), 545–562. CrossRef
Wechsler, D. (1981). WAIS-R manual: Wechsler adult intelligence scale-revised. New York: Psychological Corporation.
Wolf, J. M., & Ventola, P. (2014). Assessment and treatment planning in adults with autism spectrum disorders. In F. R. Volkmar et al. (Eds.), Adolescents and adults with autism spectrum disorders (pp. 283–298). New York: Springer. CrossRef
Zander, E., Sturm, H., & Bölte, S. (2015). The added value of the combined use of the Autism Diagnostic Interview–Revised and the Autism Diagnostic Observation Schedule: Diagnostic validity in a clinical Swedish sample of toddlers and young preschoolers. Autism: The International Journal of Research and Practice, 19(2), 187–199. CrossRef
- Diagnosing ASD in Adults Without ID: Accuracy of the ADOS-2 and the ADI-R
- Springer US