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Gepubliceerd in: Quality of Life Research 9/2020

25-05-2020

Development of algorithms to estimate EQ-5D and derive health utilities from WHOQOL-HIV Bref: a mapping study

Auteurs: Rodolfo Castro, Raquel B. De Boni, Hugo Perazzo, Beatriz Grinsztejn, Valdiléa G. Veloso, Marcelo Ribeiro-Alves

Gepubliceerd in: Quality of Life Research | Uitgave 9/2020

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Abstract

Purpose

This study aimed to develop and evaluate different families of applicable models available for utility mapping between World Health Organization Quality of Life for HIV-abbreviated version (WHOQOL-HIV Bref) and EQ-5D-3L and to propose an optimised algorithm to estimate health utilities of people living with HIV.

Methods

Estimation dataset was collected between July 2014 and September 2016 in a cross-sectional study including 1526 people living with HIV/Aids (PLWH) under care at the Instituto Nacional de Infectologia Evandro Chagas—FIOCRUZ, in Brazil. Data of WHOQOL-HIV Bref and EQ-5D-3L questionnaires were collected. Fisher’s exact tests were used for testing WHOQOL-HIV Bref response frequencies among groups of responses to each of the five EQ-5D-3L domains. Multiple correspondence analyses (MCA) were used to inspect the relationships between both instrument responses. Different families of applicable models available for utility mapping between WHOQOL-HIV Bref and EQ-5D-3L were adjusted for the prediction of disutility.

Results

Candidate models’ performances using mean absolute error (MAE), mean squared error (MSE), and root mean squared error (RMSE) were similarly good, which was evidenced by the overlapping of its 95% confidence intervals of the mean tenfold cross-validation or estimated generalisation errors. However, the Hurdle Logistic-Log-Normal model was better on average according to generalisation errors both in the prediction of Brazilian utility values (MAE = 0.1037, MSE = 0.0178, and RMSE = 0.1332) and for those of the UK (MAE = 0.1476, MSE = 0.0443, and RMSE = 0.2099).

Conclusions

Mapping EQ-5D-3L responses or deriving health utilities directly from WHOQOL-HIV Bref responses can be a valid alternative for settings with no preference-based health utility data.
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Literatuur
1.
go back to reference Gueler, A., Moser, A., Calmy, A., Gunthard, H. F., Bernasconi, E., Furrer, H., et al. (2017). Life expectancy in HIV-positive persons in Switzerland: Matched comparison with general population. Aids, 31(3), 427–436. PubMedPubMedCentral Gueler, A., Moser, A., Calmy, A., Gunthard, H. F., Bernasconi, E., Furrer, H., et al. (2017). Life expectancy in HIV-positive persons in Switzerland: Matched comparison with general population. Aids, 31(3), 427–436. PubMedPubMedCentral
2.
go back to reference Engelhard, E. A. N., Smit, C., van Dijk, P. R., Kuijper, T. M., Wermeling, P. R., Weel, A. E., et al. (2018). Health-related quality of life of people with HIV: An assessment of patient related factors and comparison with other chronic diseases. Aids, 32(1), 103–112. PubMed Engelhard, E. A. N., Smit, C., van Dijk, P. R., Kuijper, T. M., Wermeling, P. R., Weel, A. E., et al. (2018). Health-related quality of life of people with HIV: An assessment of patient related factors and comparison with other chronic diseases. Aids, 32(1), 103–112. PubMed
3.
go back to reference Parsons, T. D., Braaten, A. J., Hall, C. D., & Robertson, K. R. (2006). Better quality of life with neuropsychological improvement on HAART. Health and Quality of Life Outcomes, 4, 11. PubMedPubMedCentral Parsons, T. D., Braaten, A. J., Hall, C. D., & Robertson, K. R. (2006). Better quality of life with neuropsychological improvement on HAART. Health and Quality of Life Outcomes, 4, 11. PubMedPubMedCentral
4.
go back to reference Dessie, Z. G., Zewotir, T., Mwambi, H., & North, D. (2020). Modelling of viral load dynamics and CD4 cell count progression in an antiretroviral naive cohort: Using a joint linear mixed and multistate Markov model. BMC Infectious Diseases, 20(1), 246. PubMedPubMedCentral Dessie, Z. G., Zewotir, T., Mwambi, H., & North, D. (2020). Modelling of viral load dynamics and CD4 cell count progression in an antiretroviral naive cohort: Using a joint linear mixed and multistate Markov model. BMC Infectious Diseases, 20(1), 246. PubMedPubMedCentral
5.
go back to reference Maheswaran, H., Petrou, S., Cohen, D., MacPherson, P., Kumwenda, F., Lalloo, D. G., et al. (2018). Economic costs and health-related quality of life outcomes of hospitalised patients with high HIV prevalence: A prospective hospital cohort study in Malawi. PLoS ONE, 13(3), e0192991. PubMedPubMedCentral Maheswaran, H., Petrou, S., Cohen, D., MacPherson, P., Kumwenda, F., Lalloo, D. G., et al. (2018). Economic costs and health-related quality of life outcomes of hospitalised patients with high HIV prevalence: A prospective hospital cohort study in Malawi. PLoS ONE, 13(3), e0192991. PubMedPubMedCentral
6.
go back to reference Poudel, A. N., Newlands, D., & Simkhada, P. (2017). The economic burden of HIV/AIDS on individuals and households in Nepal: A quantitative study. BMC Health Services Research, 17(1), 76. PubMedPubMedCentral Poudel, A. N., Newlands, D., & Simkhada, P. (2017). The economic burden of HIV/AIDS on individuals and households in Nepal: A quantitative study. BMC Health Services Research, 17(1), 76. PubMedPubMedCentral
7.
go back to reference Benzaken, A. S., Pereira, G. F. M., Costa, L., Tanuri, A., Santos, A. F., & Soares, M. A. (2019). Antiretroviral treatment, government policy and economy of HIV/AIDS in Brazil: Is it time for HIV cure in the country? AIDS Research and Therapy, 16(1), 19. PubMedPubMedCentral Benzaken, A. S., Pereira, G. F. M., Costa, L., Tanuri, A., Santos, A. F., & Soares, M. A. (2019). Antiretroviral treatment, government policy and economy of HIV/AIDS in Brazil: Is it time for HIV cure in the country? AIDS Research and Therapy, 16(1), 19. PubMedPubMedCentral
8.
go back to reference Cooper, V., Clatworthy, J., Harding, R., & Whetham, J. (2017). Measuring quality of life among people living with HIV: A systematic review of reviews. Health and Quality of Life Outcomes, 15(1), 220. PubMedPubMedCentral Cooper, V., Clatworthy, J., Harding, R., & Whetham, J. (2017). Measuring quality of life among people living with HIV: A systematic review of reviews. Health and Quality of Life Outcomes, 15(1), 220. PubMedPubMedCentral
9.
go back to reference Dakin, H., Abel, L., Burns, R., & Yang, Y. (2018). Review and critical appraisal of studies mapping from quality of life or clinical measures to EQ-5D: an online database and application of the MAPS statement. Health and Quality of Life Outcomes, 16(1), 31. PubMedPubMedCentral Dakin, H., Abel, L., Burns, R., & Yang, Y. (2018). Review and critical appraisal of studies mapping from quality of life or clinical measures to EQ-5D: an online database and application of the MAPS statement. Health and Quality of Life Outcomes, 16(1), 31. PubMedPubMedCentral
10.
go back to reference EuroQol., (1990). EuroQol–a new facility for the measurement of health-related quality of life. Health Policy, 16(3), 199–208. EuroQol., (1990). EuroQol–a new facility for the measurement of health-related quality of life. Health Policy, 16(3), 199–208.
11.
go back to reference O'Connell, K. A., & Skevington, S. M. (2012). An international quality of life instrument to assess wellbeing in adults who are HIV-positive: A short form of the WHOQOL-HIV (31 items). AIDS and Behavior, 16(2), 452–460. PubMed O'Connell, K. A., & Skevington, S. M. (2012). An international quality of life instrument to assess wellbeing in adults who are HIV-positive: A short form of the WHOQOL-HIV (31 items). AIDS and Behavior, 16(2), 452–460. PubMed
12.
go back to reference Shi, Y., Thompson, J., Walker, A. S., Paton, N. I., & Cheung, Y. B. (2019). Mapping the medical outcomes study HIV health survey (MOS-HIV) to the EuroQoL 5 Dimension (EQ-5D-3 L) utility index. Health and Quality of Life Outcomes, 17(1), 83. PubMedPubMedCentral Shi, Y., Thompson, J., Walker, A. S., Paton, N. I., & Cheung, Y. B. (2019). Mapping the medical outcomes study HIV health survey (MOS-HIV) to the EuroQoL 5 Dimension (EQ-5D-3 L) utility index. Health and Quality of Life Outcomes, 17(1), 83. PubMedPubMedCentral
13.
go back to reference Joyce, V. R., Sun, H., Barnett, P. G., Bansback, N., Griffin, S. C., Bayoumi, A. M., et al. (2017). Mapping MOS-HIV to HUI3 and EQ-5D-3L in Patients With HIV. MDM Policy & Practice, 2(2), 2381468317716440. Joyce, V. R., Sun, H., Barnett, P. G., Bansback, N., Griffin, S. C., Bayoumi, A. M., et al. (2017). Mapping MOS-HIV to HUI3 and EQ-5D-3L in Patients With HIV. MDM Policy & Practice, 2(2), 2381468317716440.
14.
go back to reference Ali, F. M., Kay, R., Finlay, A. Y., Piguet, V., Kupfer, J., Dalgard, F., et al. (2017). Mapping of the DLQI scores to EQ-5D utility values using ordinal logistic regression. Quality of Life Research, 26(11), 3025–3034. PubMedPubMedCentral Ali, F. M., Kay, R., Finlay, A. Y., Piguet, V., Kupfer, J., Dalgard, F., et al. (2017). Mapping of the DLQI scores to EQ-5D utility values using ordinal logistic regression. Quality of Life Research, 26(11), 3025–3034. PubMedPubMedCentral
15.
go back to reference Collado-Mateo, D., Chen, G., Garcia-Gordillo, M. A., Iezzi, A., Adsuar, J. C., Olivares, P. R., et al. (2017). Fibromyalgia and quality of life: Mapping the revised fibromyalgia impact questionnaire to the preference-based instruments. Health and Quality of Life Outcomes, 15(1), 114. PubMedPubMedCentral Collado-Mateo, D., Chen, G., Garcia-Gordillo, M. A., Iezzi, A., Adsuar, J. C., Olivares, P. R., et al. (2017). Fibromyalgia and quality of life: Mapping the revised fibromyalgia impact questionnaire to the preference-based instruments. Health and Quality of Life Outcomes, 15(1), 114. PubMedPubMedCentral
16.
go back to reference Mpundu-Kaambwa, C., Chen, G., Russo, R., Stevens, K., Petersen, K. D., & Ratcliffe, J. (2017). Mapping CHU9D Utility Scores from the PedsQLTM 4 0 SF-15. Pharmacoeconomics, 35(4), 453–467. PubMed Mpundu-Kaambwa, C., Chen, G., Russo, R., Stevens, K., Petersen, K. D., & Ratcliffe, J. (2017). Mapping CHU9D Utility Scores from the PedsQLTM 4 0 SF-15. Pharmacoeconomics, 35(4), 453–467. PubMed
17.
go back to reference Wong, C. K. H., Cheung, P. W. H., Samartzis, D., Luk, K. D., Cheung, K. M. C., Lam, C. L. K., et al. (2017). Mapping the SRS-22r questionnaire onto the EQ-5D-5L utility score in patients with adolescent idiopathic scoliosis. PLoS ONE, 12(4), e0175847. PubMedPubMedCentral Wong, C. K. H., Cheung, P. W. H., Samartzis, D., Luk, K. D., Cheung, K. M. C., Lam, C. L. K., et al. (2017). Mapping the SRS-22r questionnaire onto the EQ-5D-5L utility score in patients with adolescent idiopathic scoliosis. PLoS ONE, 12(4), e0175847. PubMedPubMedCentral
18.
go back to reference Round, J., & Hawton, A. (2017). Statistical alchemy: Conceptual validity and mapping to generate health state utility values. PharmacoEconomics - Open, 1(4), 233–239. PubMedPubMedCentral Round, J., & Hawton, A. (2017). Statistical alchemy: Conceptual validity and mapping to generate health state utility values. PharmacoEconomics - Open, 1(4), 233–239. PubMedPubMedCentral
19.
go back to reference NICE. (2013). Guide to the methods of technology appraisal 2013. Manchester: National Institute for Health and Care Excellence. NICE. (2013). Guide to the methods of technology appraisal 2013. Manchester: National Institute for Health and Care Excellence.
20.
go back to reference Petrou, S., Rivero-Arias, O., Dakin, H., Longworth, L., Oppe, M., Froud, R., et al. (2015). The MAPS reporting statement for studies mapping onto generic preference-based outcome measures: Explanation and elaboration. Pharmacoeconomics, 33(10), 993–1011. PubMed Petrou, S., Rivero-Arias, O., Dakin, H., Longworth, L., Oppe, M., Froud, R., et al. (2015). The MAPS reporting statement for studies mapping onto generic preference-based outcome measures: Explanation and elaboration. Pharmacoeconomics, 33(10), 993–1011. PubMed
21.
go back to reference Petrou, S., Rivero-Arias, O., Dakin, H., Longworth, L., Oppe, M., Froud, R., et al. (2016). Preferred reporting items for studies mapping onto preference-based outcome measures: The MAPS statement. Quality of Life Research, 25(2), 275–281. PubMed Petrou, S., Rivero-Arias, O., Dakin, H., Longworth, L., Oppe, M., Froud, R., et al. (2016). Preferred reporting items for studies mapping onto preference-based outcome measures: The MAPS statement. Quality of Life Research, 25(2), 275–281. PubMed
22.
go back to reference Rencz, F., Gulacsi, L., Drummond, M., Golicki, D., Prevolnik Rupel, V., Simon, J., et al. (2016). EQ-5D in central and Eastern Europe: 2000–2015. Quality of Life Research, 25(11), 2693–2710. PubMed Rencz, F., Gulacsi, L., Drummond, M., Golicki, D., Prevolnik Rupel, V., Simon, J., et al. (2016). EQ-5D in central and Eastern Europe: 2000–2015. Quality of Life Research, 25(11), 2693–2710. PubMed
23.
go back to reference Sassi, F. (2006). Calculating QALYs, comparing QALY and DALY calculations. Health Policy and Planning, 21(5), 402–408. PubMed Sassi, F. (2006). Calculating QALYs, comparing QALY and DALY calculations. Health Policy and Planning, 21(5), 402–408. PubMed
24.
go back to reference Feng, Y., Parkin, D., & Devlin, N. J. (2014). Assessing the performance of the EQ-VAS in the NHS PROMs programme. Quality of Life Research, 23(3), 977–989. PubMed Feng, Y., Parkin, D., & Devlin, N. J. (2014). Assessing the performance of the EQ-VAS in the NHS PROMs programme. Quality of Life Research, 23(3), 977–989. PubMed
25.
go back to reference Castro, R., De Boni, R. B., Luz, P. M., Velasque, L., Lopes, L. V., Medina-Lara, A., et al. (2019). Health-related quality of life assessment among people living with HIV in Rio de Janeiro, Brazil: A cross-sectional study. Quality of Life Research, 28(4), 1035–1045. PubMed Castro, R., De Boni, R. B., Luz, P. M., Velasque, L., Lopes, L. V., Medina-Lara, A., et al. (2019). Health-related quality of life assessment among people living with HIV in Rio de Janeiro, Brazil: A cross-sectional study. Quality of Life Research, 28(4), 1035–1045. PubMed
26.
go back to reference Santos, M., Cintra, M. A., Monteiro, A. L., Santos, B., Gusmao-Filho, F., Andrade, M. V., et al. (2016). Brazilian valuation of EQ-5D-3L health states: Results from a Saturation Study. Medical Decision Making, 36(2), 253–263. PubMed Santos, M., Cintra, M. A., Monteiro, A. L., Santos, B., Gusmao-Filho, F., Andrade, M. V., et al. (2016). Brazilian valuation of EQ-5D-3L health states: Results from a Saturation Study. Medical Decision Making, 36(2), 253–263. PubMed
27.
go back to reference R CoreTeam. (2018). R: A language and environment for statistical computing. Vienna: R Foundation for Statistical Computing. R CoreTeam. (2018). R: A language and environment for statistical computing. Vienna: R Foundation for Statistical Computing.
28.
go back to reference Lê, S., Josse, J., & Husson, F. (2008). FactoMineR: An R package for multivariate analysis. Journal of Statistical Software, 25(1), 18. Lê, S., Josse, J., & Husson, F. (2008). FactoMineR: An R package for multivariate analysis. Journal of Statistical Software, 25(1), 18.
29.
go back to reference Dunn, P. K., & Smyth, G. K. (2005). Series evaluation of Tweedie exponential dispersion model densities. Statistics and Computing, 15(4), 267–280. Dunn, P. K., & Smyth, G. K. (2005). Series evaluation of Tweedie exponential dispersion model densities. Statistics and Computing, 15(4), 267–280.
30.
go back to reference Dunn, P. K., & Smyth, G. K. (2008). Evaluation of Tweedie exponential dispersion model densities by Fourier inversion. Statistics and Computing, 18(1), 73–86. Dunn, P. K., & Smyth, G. K. (2008). Evaluation of Tweedie exponential dispersion model densities by Fourier inversion. Statistics and Computing, 18(1), 73–86.
31.
go back to reference Therneau, T. M. G., & P. M., (2000). Modeling survival data: Extending the cox model. New York: Springer. Therneau, T. M. G., & P. M., (2000). Modeling survival data: Extending the cox model. New York: Springer.
32.
go back to reference Crott, R. (2018). Direct mapping of the QLQ-C30 to EQ-5D preferences: A comparison of regression methods. PharmacoEconomics Open, 2(2), 165–177. PubMed Crott, R. (2018). Direct mapping of the QLQ-C30 to EQ-5D preferences: A comparison of regression methods. PharmacoEconomics Open, 2(2), 165–177. PubMed
33.
go back to reference Wee, H. L., Yeo, K. K., Chong, K. J., Khoo, E. Y. H., & Cheung, Y. B. (2018). Mean rank, equipercentile, and regression mapping of World Health Organization quality of life brief (WHOQOL-BREF) to EuroQoL 5 dimensions 5 levels (EQ-5D-5L) Utilities. Medical Decision Making, 38(3), 319–333. PubMed Wee, H. L., Yeo, K. K., Chong, K. J., Khoo, E. Y. H., & Cheung, Y. B. (2018). Mean rank, equipercentile, and regression mapping of World Health Organization quality of life brief (WHOQOL-BREF) to EuroQoL 5 dimensions 5 levels (EQ-5D-5L) Utilities. Medical Decision Making, 38(3), 319–333. PubMed
34.
go back to reference Hua, A. Y., Westin, O., Hamrin Senorski, E., Svantesson, E., Grassi, A., Zaffagnini, S., et al. (2018). Mapping functions in health-related quality of life: mapping from the Achilles Tendon Rupture Score to the EQ-5D. Knee Surgery, Sports Traumatology, Arthroscopy, 26(10), 3083–3088. PubMedPubMedCentral Hua, A. Y., Westin, O., Hamrin Senorski, E., Svantesson, E., Grassi, A., Zaffagnini, S., et al. (2018). Mapping functions in health-related quality of life: mapping from the Achilles Tendon Rupture Score to the EQ-5D. Knee Surgery, Sports Traumatology, Arthroscopy, 26(10), 3083–3088. PubMedPubMedCentral
35.
go back to reference Maertens de Noordhout, C., Devleesschauwer, B., Gielens, L., Plasmans, M. H. D., Haagsma, J. A., & Speybroeck, N. (2017). Mapping EQ-5D utilities to GBD 2010 and GBD 2013 disability weights: Results of two pilot studies in Belgium. Arch Public Health, 75, 6. PubMedPubMedCentral Maertens de Noordhout, C., Devleesschauwer, B., Gielens, L., Plasmans, M. H. D., Haagsma, J. A., & Speybroeck, N. (2017). Mapping EQ-5D utilities to GBD 2010 and GBD 2013 disability weights: Results of two pilot studies in Belgium. Arch Public Health, 75, 6. PubMedPubMedCentral
36.
go back to reference Gray, A. M., Rivero-Arias, O., & Clarke, P. M. (2006). Estimating the association between SF-12 responses and EQ-5D utility values by response mapping. Medical Decision Making, 26(1), 18–29. PubMed Gray, A. M., Rivero-Arias, O., & Clarke, P. M. (2006). Estimating the association between SF-12 responses and EQ-5D utility values by response mapping. Medical Decision Making, 26(1), 18–29. PubMed
37.
go back to reference Dakin, H., Gray, A., & Murray, D. (2013). Mapping analyses to estimate EQ-5D utilities and responses based on Oxford Knee Score. Quality of Life Research, 22(3), 683–694. PubMed Dakin, H., Gray, A., & Murray, D. (2013). Mapping analyses to estimate EQ-5D utilities and responses based on Oxford Knee Score. Quality of Life Research, 22(3), 683–694. PubMed
38.
go back to reference Mukuria, C., Rowen, D., Harnan, S., Rawdin, A., Wong, R., Ara, R., et al. (2019). An updated systematic review of studies mapping (or cross-walking) measures of health-related quality of life to generic preference-based measures to generate utility values. Applied Health Economics and Health Policy, 17(3), 295–313. PubMed Mukuria, C., Rowen, D., Harnan, S., Rawdin, A., Wong, R., Ara, R., et al. (2019). An updated systematic review of studies mapping (or cross-walking) measures of health-related quality of life to generic preference-based measures to generate utility values. Applied Health Economics and Health Policy, 17(3), 295–313. PubMed
39.
go back to reference Kiadaliri, A. A., & Englund, M. (2016). Assessing the external validity of algorithms to estimate EQ-5D-3L from the WOMAC. Health and Quality of Life Outcomes, 14(1), 141. PubMedPubMedCentral Kiadaliri, A. A., & Englund, M. (2016). Assessing the external validity of algorithms to estimate EQ-5D-3L from the WOMAC. Health and Quality of Life Outcomes, 14(1), 141. PubMedPubMedCentral
40.
go back to reference Kent, S., Gray, A., Schlackow, I., Jenkinson, C., & McIntosh, E. (2015). Mapping from the Parkinson's Disease Questionnaire PDQ-39 to the Generic EuroQol EQ-5D-3L: The value of mixture models. Medical Decision Making, 35(7), 902–911. PubMed Kent, S., Gray, A., Schlackow, I., Jenkinson, C., & McIntosh, E. (2015). Mapping from the Parkinson's Disease Questionnaire PDQ-39 to the Generic EuroQol EQ-5D-3L: The value of mixture models. Medical Decision Making, 35(7), 902–911. PubMed
41.
go back to reference Gabbe, B. J., McDermott, E., Simpson, P. M., Derrett, S., Ameratunga, S., Polinder, S., et al. (2015). Level of agreement between patient-reported EQ-5D responses and EQ-5D responses mapped from the SF-12 in an injury population. Population Health Metrics, 13, 14. PubMedPubMedCentral Gabbe, B. J., McDermott, E., Simpson, P. M., Derrett, S., Ameratunga, S., Polinder, S., et al. (2015). Level of agreement between patient-reported EQ-5D responses and EQ-5D responses mapped from the SF-12 in an injury population. Population Health Metrics, 13, 14. PubMedPubMedCentral
Metagegevens
Titel
Development of algorithms to estimate EQ-5D and derive health utilities from WHOQOL-HIV Bref: a mapping study
Auteurs
Rodolfo Castro
Raquel B. De Boni
Hugo Perazzo
Beatriz Grinsztejn
Valdiléa G. Veloso
Marcelo Ribeiro-Alves
Publicatiedatum
25-05-2020
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 9/2020
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-020-02534-1

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