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Quality of Life Research

Gepubliceerd in:

01-05-2016

Developing a measure of medication-related quality of life for people with polypharmacy

Auteurs: Hsu-Min Tseng, Chia-Hui Lee, Yin-Jen Chen, Hsiang-Hao Hsu, Li-Yueh Huang, Jing-Long Huang

Gepubliceerd in: Quality of Life Research | Uitgave 5/2016

Abstract

Purpose

To develop a measure of medication-related quality of life (MRQoL) and to validate the measure in a hospital-based population of patients with polypharmacy.

Methods

The Medication-Related Quality of Life Scale version 1.0 (MRQoLS-v1.0) included 14 items developed on the basis of interviews with elderly patients with polypharmacy, defined as taking five or more medications simultaneously. This scale was tested in 219 outpatients (99 with polypharmacy and 120 without polypharmacy). Two measures were used to establish construct validity the Psychological Distress Checklist, for convergent validity, and the Medication Adherence Behavior Scale (MABS), for discriminant validity.

Results

The 14-item scale was found to be both reliable and valid. Internal consistency reliability evaluated using Cronbach’s alpha for this scale was 0.91. Scores on the MRQoLS-v1.0 correlated statistically significantly and negatively with those on the Psychological Distress Checklist. Discriminant validity was demonstrated by low correlation with MABS, indicating that the MRQoLS-v1.0 measured concepts different from medication adherence. Significant differences in the MRQoLS-v1.0 between patients with polypharmacy and those without polypharmacy provided evidence for known-group validity.

Conclusions

The study presents a psychometric evaluation of a measure used to assess MRQoL of patients with polypharmacy. The instrument is practical to administer in clinics and provides a valuable adjunct to the outcome measurement for patients with polypharmacy. Further research on the sensitivity of this instrument to medication change in multi-medicated patients is warranted.

vorige artikel The course of health status and (health-related) quality of life following fracture of the lower extremity: a 6-month follow-up study

volgende artikel Validation of the Recovery Assessment Scale for Chinese in recovery of mental illness in Hong Kong

Patterson, S. M., Hughes, C., Kerse, N., Cardwell, C. R., & Bradley, M. C. (2012). Interventions to improve the appropriate use of polypharmacy for older people. The Cochrane Database of Systematic Reviews,. doi:10.1002/14651858.CD008165.pub2.PubMed

Kaufman, D. W., Kelly, J. P., Rosenberg, L., Anderson, T. E., & Mitchell, A. A. (2002). Recent patterns of medication use in the ambulatory adult population of the United States: The Slone survey. JAMA, 287(3), 337–344.CrossRefPubMed

Ware, J. E, Jr, & Gandek, B. (1998). Overview of the SF-36 health survey and the international quality of life assessment (IQOLA) project. Journal of Clinical Epidemiology, 51(11), 903–912.CrossRefPubMed

Henderson, J. A., Buchwald, D., & Manson, S. M. (2006). Relationship of medication use to health-related quality of life among a group of older American Indians. Journal of Applied Gerontology, 25(1 suppl), 89S–104S. doi:10.1177/0733464805283035.CrossRef

Chumney, E. C., & Robinson, L. C. (2006). The effects of pharmacist interventions on patients with polypharmacy. Pharmacy Practice, 4(3), 103–109.CrossRefPubMedPubMedCentral

Hanlon, J. T., Weinberger, M., Samsa, G. P., Schmader, K. E., Uttech, K. M., Lewis, I. K., et al. (1996). A randomized, controlled trial of a clinical pharmacist intervention to improve inappropriate prescribing in elderly outpatients with polypharmacy. American Journal of Medicine, 100(4), 428–437. doi:10.1016/S0002-9343(97)89519-8.CrossRefPubMed

Krska, J., Cromarty, J. A., Arris, F., Jamieson, D., Hansford, D., Duffus, P. R., et al. (2001). Pharmacist-led medication review in patients over 65: A randomized, controlled trial in primary care. Age and Ageing, 30(3), 205–211.CrossRefPubMed

Taylor, C. T., Byrd, D. C., & Krueger, K. (2003). Improving primary care in rural Alabama with a pharmacy initiative. American Journal of Health-System Pharmacy, 60(11), 1123–1129.PubMed

Barbera, M., Sanjuan, J., Munarriz, M., Novella, E., Santiago, C., & Simo, M. (2006). Subjective experience with antipsychotics: Quantitative evaluation. Actas Españolas de Psiquiatría: Acepsi, 34(5), 287–294.PubMed

10.

Hogan, T. P., Awad, A. G., & Eastwood, R. (1983). A self-report scale predictive of drug compliance in schizophrenics: Reliability and discriminative validity. Psychological Medicine, 13(1), 177–183.CrossRefPubMed

11.

Morisky, D. E., Green, L. W., & Levine, D. M. (1986). Concurrent and predictive validity of a self-reported measure of medication adherence. Medical Care, 24(1), 67–74.CrossRefPubMed

12.

Naber, D. (1995). A self-rating to measure subjective effects of neuroleptic drugs, relationships to objective psychopathology, quality of life, compliance and other clinical variables. International Clinical Psychopharmacology, 10(Suppl 3), 133–138.PubMed

13.

World Health Organization. (1980). The international classification of impairments, disabilities, and handicaps. Geneva: WHO.

14.

Ford, H. L., Gerry, E., Tennant, A., Whalley, D., Haigh, R., & Johnson, M. H. (2001). Developing a disease-specific quality of life measure for people with multiple sclerosis. Clinical Rehabilitation, 15(3), 247–258.CrossRefPubMed

15.

De Haan, L., Weisfelt, M., Dingemans, P. M., Linszen, D. H., & Wouters, L. (2002). Psychometric properties of the subjective well-being under neuroleptics scale and the subjective deficit syndrome scale. Psychopharmacology (Berl), 162(1), 24–28. doi:10.1007/s00213-002-1054-x.CrossRef

16.

Makai, P., Brouwer, W. B., Koopmanschap, M. A., Stolk, E. A., & Nieboer, A. P. (2014). Quality of life instruments for economic evaluations in health and social care for older people: A systematic review. Social Science and Medicine, 102, 83–93. doi:10.1016/j.socscimed.2013.11.050.CrossRefPubMed

17.

Chen, C. Y., & Wu, E. C. (1987). A biopsychosocial model to assess the psychosomatic symptoms in college students of National Taiwan University. Formosa Journal of Mental Health, 3, 89–105.

18.

Tseng, H.-M., Lu, J.-F. R., & Gandek, B. (2003). Cultural issues in using the SF-36 health survey in Asia: Results from Taiwan. Health and Quality of Life Outcomes, 1, 72.CrossRefPubMedPubMedCentral

19.

Yen, C. F., Chen, C. S., Ko, C. H., Yeh, M. L., Yang, S. J., Yen, J. Y., et al. (2005). Relationships between insight and medication adherence in outpatients with schizophrenia and bipolar disorder: Prospective study. Psychiatry and Clinical Neurosciences, 59(4), 403–409. doi:10.1111/j.1440-1819.2005.01392.x.CrossRefPubMed

20.

Blackwell, B. (1976). Treatment adherence. British Journal of Psychiatry, 129, 513–531.CrossRefPubMed

21.

Diener, E. (2012). New findings and future directions for subjective well-being research. American Psychologist, 67(8), 590–597. doi:10.1037/a0029541.CrossRefPubMed

22.

Taylor, S. E., & Brown, J. D. (1988). Illusion and well-being: A social psychological perspective on mental health. Psychological Bulletin, 103(2), 193–210.CrossRefPubMed

23.

Atkinson, M. J., Sinha, A., Hass, S. L., Colman, S. S., Kumar, R. N., Brod, M., et al. (2004). Validation of a general measure of treatment satisfaction, the Treatment Satisfaction Questionnaire for Medication (TSQM), using a national panel study of chronic disease. Health and Quality of Life Outcomes, 2, 12. doi:10.1186/1477-7525-2-12.CrossRefPubMedPubMedCentral

Titel: Developing a measure of medication-related quality of life for people with polypharmacy
Auteurs: Hsu-Min Tseng
Chia-Hui Lee
Yin-Jen Chen
Hsiang-Hao Hsu
Li-Yueh Huang
Jing-Long Huang
Publicatiedatum: 01-05-2016
Uitgeverij: Springer International Publishing
Gepubliceerd in: Quality of Life Research / Uitgave 5/2016
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-015-1177-2

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Abstract

Purpose

Methods

Results

Conclusions

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