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25-06-2016 | Uitgave 12/2016

Quality of Life Research 12/2016

Deriving population norms for the AQoL-6D and AQoL-8D multi-attribute utility instruments from web-based data

Tijdschrift:
Quality of Life Research > Uitgave 12/2016
Auteurs:
Aimee Maxwell, Mehmet Özmen, Angelo Iezzi, Jeff Richardson
Belangrijke opmerkingen

Electronic supplementary material

The online version of this article (doi:10.​1007/​s11136-016-1337-z) contains supplementary material, which is available to authorized users.

Abstract

Objectives

(i) to demonstrate a method which ameliorates the problem of self-selection in the estimation of population norms from web-based data and (ii) to use the method to calculate population norms for two multi-attribute utility (MAU) instruments, the AQoL-6D and AQoL-8D, and population norms for the sub-scales from which they are constructed.

Methods

A web-based survey administered the AQoL-8D MAU instrument (which subsumes the AQoL-6D questionnaire), to members of the public along with the AQoL-4D which has extant population norms. Age, gender and the AQoL-4D were used as post-stratification auxiliary variables to construct weights to ameliorate the potential effects of self-selection associated with web-based surveys. The weights were used to estimate unbiased population norms. Standard errors from the weighted samples were calculated using Jackknife estimation.

Results

For both AQoL-6D and AQoL-8D, physical health dimensions decline significantly with age. In contrast, for the majority of the psycho-social dimensions there is a significant U-shaped profile. The net effect is a shallow U-shaped relationship between age and both the AQoL-6D and AQoL-8D utilities. This contrasts with the almost monotonic decline in the utilities derived from the AQoL-4D and SF-6D MAU instruments.

Conclusions

Post-stratification weights were used to ameliorate potential bias in the derivation of norms from web-based data for the AQoL-6D and AQoL-8D. The methods may be used generally to obtain norms when suitable auxiliary variables are available. The inclusion of an enlarged psycho-social component in the two instruments significantly alters the demographic profile.

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Extra materiaal
Supplementary material 1 (DOCX 37 kb)
11136_2016_1337_MOESM1_ESM.docx
Literatuur
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