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Gepubliceerd in: Quality of Life Research 12/2019

24-08-2019

Depressive symptoms, physical symptoms, and health-related quality of life among older adults with HIV

Auteurs: Blair Olson, Wilson Vincent, Jaimie P. Meyer, Trace Kershaw, Kathleen J. Sikkema, Timothy G. Heckman, Nathan B. Hansen

Gepubliceerd in: Quality of Life Research | Uitgave 12/2019

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Abstract

Purpose

In the United States, approximately 45% of persons living with HIV (PLHIV) are ≥ 50 years of age. Many older PLHIV have multi-morbidities that complicate HIV infection and/or interfere with, or are exacerbated by, antiretroviral treatment. Physical health symptoms and psychiatric disorders, particularly depression, can worsen life quality in older PLHIV.

Methods

This study assessed associations among physical symptoms, indicators of HIV-related health status (i.e., time since diagnosis; ever diagnosed with AIDS; having attained viral suppression), depressive symptoms, and health-related quality of life (HRQoL) in older PLHIV. Regression analyses examined data from 296 PLHIV ≥ 50 years of age living in Cincinnati, OH, Columbus, OH, and New York City.

Results

Depressive symptoms and physical symptoms, particularly those related to appearance and sexual functioning, most strongly predicted HRQoL. Indicators of HIV health status did not significantly predict HRQoL. Depressive symptoms were a particularly robust predictor of HRQoL, even when accounting for physical health symptoms.

Conclusion

Findings suggest that symptom management is critical to HRQoL in older PLHIV, and symptoms related to physical appearance and sexual functioning should not be overlooked in this growing population.
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Metagegevens
Titel
Depressive symptoms, physical symptoms, and health-related quality of life among older adults with HIV
Auteurs
Blair Olson
Wilson Vincent
Jaimie P. Meyer
Trace Kershaw
Kathleen J. Sikkema
Timothy G. Heckman
Nathan B. Hansen
Publicatiedatum
24-08-2019
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 12/2019
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-019-02271-0

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