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01-06-2015

Depressive symptoms and spiritual wellbeing in asymptomatic heart failure patients

Auteurs: Paul J. Mills, Kathleen Wilson, Navaid Iqbal, Fatima Iqbal, Milagros Alvarez, Meredith A. Pung, Katherine Wachmann, Thomas Rutledge, Jeanne Maglione, Sid Zisook, Joel E. Dimsdale, Ottar Lunde, Barry H. Greenberg, Alan Maisel, Ajit Raisinghani, Loki Natarajan, Shamini Jain, David J. Hufford, Laura Redwine

Gepubliceerd in: Journal of Behavioral Medicine | Uitgave 3/2015

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Abstract

Depression adversely predicts prognosis in individuals with symptomatic heart failure. In some clinical populations, spiritual wellness is considered to be a protective factor against depressive symptoms. This study examined associations among depressive symptoms, spiritual wellbeing, sleep, fatigue, functional capacity, and inflammatory biomarkers in 132 men and women with asymptomatic stage B heart failure (age 66.5 years ± 10.5). Approximately 32 % of the patients scored ≥10 on the Beck Depression Inventory, indicating potentially clinically relevant depressive symptoms. Multiple regression analysis predicting fewer depressive symptoms included the following significant variables: a lower inflammatory score comprised of disease-relevant biomarkers (p < 0.02), less fatigue (p < 0.001), better sleep (p < 0.04), and more spiritual wellbeing (p < 0.01) (overall model F = 26.6, p < 0.001, adjusted R square = 0.629). Further analyses indicated that the meaning (p < 0.01) and peace (p < 0.01) subscales, but not the faith (p = 0.332) subscale, of spiritual wellbeing were independently associated with fewer depressive symptoms. Interventions aimed at increasing spiritual wellbeing in patients lives, and specifically meaning and peace, may be a potential treatment target for depressive symptoms asymptomatic heart failure.
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Metagegevens
Titel
Depressive symptoms and spiritual wellbeing in asymptomatic heart failure patients
Auteurs
Paul J. Mills
Kathleen Wilson
Navaid Iqbal
Fatima Iqbal
Milagros Alvarez
Meredith A. Pung
Katherine Wachmann
Thomas Rutledge
Jeanne Maglione
Sid Zisook
Joel E. Dimsdale
Ottar Lunde
Barry H. Greenberg
Alan Maisel
Ajit Raisinghani
Loki Natarajan
Shamini Jain
David J. Hufford
Laura Redwine
Publicatiedatum
01-06-2015
Uitgeverij
Springer US
Gepubliceerd in
Journal of Behavioral Medicine / Uitgave 3/2015
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521
DOI
https://doi.org/10.1007/s10865-014-9615-0

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