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02-01-2018 | Heart Beat | Uitgave 6/2018 Open Access

Netherlands Heart Journal 6/2018

Delayed neointimal healing pattern after bioresorbable scaffold implantation

Netherlands Heart Journal > Uitgave 6/2018
D. Ochijewicz, M. Tomaniak, J. Kochman, L. Koltowski, A. Rdzanek, A. Pietrasik, G. Opolski
A 67-year-old male underwent primary percutaneous coronary intervention for inferior ST-segment elevation myocardial infarction. The patient further underwent aspiration thrombectomy, abciximab infusion and predilatation with subsequent implantation of two bioresorbable scaffolds followed by post-dilatation with a non-compliant balloon in the right coronary artery. The optical coherence tomography (OCT) confirmed good scaffold expansion, with focally malapposed struts in the distal 3‑mm scaffold segment. Twelve months later, at the prespecified evaluation, the vessel was patent without evidence of restenosis or thrombus, however, the OCT revealed a substantial rate of uncovered struts (8.5%). Interestingly, all struts were covered by neointima at the 24-month examination. Based on these findings, prolonged dual antiplatelet therapy was ceased after two years from the index procedure. Discontinuation of P2Y12 antagonist at 12 months potentially could have led to late scaffold thrombosis in our patient with initially impaired endothelial healing response (see Fig.  1).

Conflict of interest

D. Ochijewicz, M. Tomaniak, J. Kochman, L. Koltowski, A. Rdzanek, A. Pietrasik and G. Opolski declare that they have no competing interests.
Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://​creativecommons.​org/​licenses/​by/​4.​0/​), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Netherlands Heart Journal

Het Netherlands Heart Journal wordt uitgegeven in samenwerking met de Nederlandse Vereniging voor Cardiologie en de Nederlandse Hartstichting. Het tijdschrift is Engelstalig en wordt gratis beschikbaa ...

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