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03-12-2018 | Original Paper | Uitgave 4/2019

Decreased Cortical Thickness in the Anterior Cingulate Cortex in Adults with Autism

Tijdschrift:: Journal of Autism and Developmental Disorders > Uitgave 4/2019

Auteurs:: Charles Laidi, Jennifer Boisgontier, Amicie de Pierrefeu, Edouard Duchesnay, Sevan Hotier, Marc-Antoine d’Albis, Richard Delorme, Federico Bolognani, Christian Czech, Céline Bouquet, Anouck Amestoy, Julie Petit, Štefan Holiga, Juergen Dukart, Alexandru Gaman, Elie Toledano, Myriam Ly-Le Moal, Isabelle Scheid, Marion Leboyer, Josselin Houenou

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The online version of this article (https://doi.org/10.1007/s10803-018-3807-3) contains supplementary material, which is available to authorized users.

Abstract

Autism spectrum disorder (ASD) is a developmental disorder underdiagnosed in adults. To date, no consistent evidence of alterations in brain structure has been reported in adults with ASD and few studies were conducted at that age. We analyzed structural magnetic resonance imaging data from 167 high functioning adults with ASD and 195 controls. We ran our analyses on a discovery (n = 301) and a replication sample (n = 61). The right caudal anterior cingulate cortical thickness was significantly thinner in adults with ASD compared to controls in both the discovery and the replication sample. Our work underlines the relevance of studying the brain anatomy of an adult ASD population.

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Cascio, C. J., Foss-Feig, J. H., Heacock, J., Schauder, K. B., Loring, W. A., Rogers, B. P., et al. (2014). Affective neural response to restricted interests in Autism Spectrum Disorders. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 55(2), 162–171. https://doi.org/10.1111/jcpp.12147. CrossRefPubMed

Constantino, J. N., Davis, S. A., Todd, R. D., Schindler, M. K., Gross, M. M., Brophy, S. L., et al. (2003). Validation of a brief quantitative measure of autistic traits: Comparison of the social responsiveness scale with the autism diagnostic interview-revised. Journal of Autism and Developmental Disorders, 33(4), 427–433. CrossRefPubMed

Desikan, R. S., Ségonne, F., Fischl, B., Quinn, B. T., Dickerson, B. C., Blacker, D., et al. (2006). An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. NeuroImage, 31(3), 968–980. https://doi.org/10.1016/j.neuroimage.2006.01.021. CrossRef

Di Martino, A., Yan, C.-G., Li, Q., Denio, E., Castellanos, F. X., Alaerts, K., et al. (2014). The autism brain imaging data exchange: Towards a large-scale evaluation of the intrinsic brain architecture in autism. Molecular Psychiatry, 19(6), 659–667. https://doi.org/10.1038/mp.2013.78. CrossRefPubMed

Dougherty, C. C., Evans, D. W., Katuwal, G. J., & Michael, A. M. (2016). Asymmetry of fusiform structure in autism spectrum disorder: Trajectory and association with symptom severity. Molecular Autism, 7, 28. https://doi.org/10.1186/s13229-016-0089-5. CrossRefPubMedPubMedCentral

Eaves, L. C., Ho, H. H., & Eaves, D. M. (1994). Subtypes of autism by cluster analysis. Journal of Autism and Developmental Disorders, 24(1), 3–22. CrossRefPubMed

Ecker, C., Ginestet, C., Feng, Y., Johnston, P., Lombardo, M. V., Lai, M. C., et al. (2013). Brain surface anatomy in adults with autism: The relationship between surface area, cortical thickness, and autistic symptoms. JAMA Psychiatry, 70(1), 59–70. https://doi.org/10.1001/jamapsychiatry.2013.265. CrossRefPubMed

Ecker, C., Suckling, J., Deoni, S. C., Lombardo, M. V., Bullmore, E. T., & Baron-Cohen, S. et al. (2012). Brain anatomy and its relationship to behavior in adults with autism spectrum disorder: A multicenter magnetic resonance imaging study. Archives of General Psychiatry, 69(2), 195–209. https://doi.org/10.1001/archgenpsychiatry.2011.1251. CrossRefPubMed

Eilam-Stock, T., Wu, T., Spagna, A., Egan, L. J., & Fan, J. (2016). Neuroanatomical alterations in high-functioning adults with autism spectrum disorder. Frontiers in Neuroscience, 10, 237. https://doi.org/10.3389/fnins.2016.00237. CrossRefPubMedPubMedCentral

Ellegood, J., Anagnostou, E., Babineau, B. A., Crawley, J. N., Lin, L., Genestine, M., et al. (2015). Clustering autism: Using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity. Molecular Psychiatry, 20(1), 118–125. https://doi.org/10.1038/mp.2014.98. CrossRefPubMed

Ernst, J., Böker, H., Hättenschwiler, J., Schüpbach, D., Northoff, G., Seifritz, E., & Grimm, S. (2014). The association of interoceptive awareness and alexithymia with neurotransmitter concentrations in insula and anterior cingulate. Social Cognitive and Affective Neuroscience, 9(6), 857–863. https://doi.org/10.1093/scan/nst058. CrossRefPubMed

Fischl, B., & Dale, A. M. (2000). Measuring the thickness of the human cerebral cortex from magnetic resonance images. Proceedings of the National Academy of Sciences of the United States of America, 97(20), 11050–11055. https://doi.org/10.1073/pnas.200033797. CrossRefPubMedPubMedCentral

Fountain, C., Winter, A. S., & Bearman, P. S. (2012). Six developmental trajectories characterize children with autism. Pediatrics. https://doi.org/10.1542/peds.2011-1601. CrossRefPubMedPubMedCentral

Gaigg, S. B., Cornell, A. S., & Bird, G. (2016). The psychophysiological mechanisms of alexithymia in autism spectrum disorder. Autism: The International Journal of Research and Practice. https://doi.org/10.1177/1362361316667062. CrossRef

Haar, S., Berman, S., Behrmann, M., & Dinstein, I. (2016). Anatomical abnormalities in Autism? Cerebral Cortex, 26(4), 1440–1452. https://doi.org/10.1093/cercor/bhu242. CrossRefPubMed

Helles, A., Gillberg, C. I., Gillberg, C., & Billstedt, E. (2015). Asperger syndrome in males over two decades: Stability and predictors of diagnosis. Journal of Child Psychology and Psychiatry, 56(6), 711–718. https://doi.org/10.1111/jcpp.12334. CrossRefPubMed

Hogeveen, J., Bird, G., Chau, A., Krueger, F., & Grafman, J. (2016). Acquired alexithymia following damage to the anterior insula. Neuropsychologia, 82, 142–148. https://doi.org/10.1016/j.neuropsychologia.2016.01.021. CrossRefPubMedPubMedCentral

Jeste, S. S., & Geschwind, D. H. (2014). Disentangling the heterogeneity of autism spectrum disorder through genetic findings. Nature Reviews. Neurology, 10(2), 74–81. https://doi.org/10.1038/nrneurol.2013.278. CrossRefPubMedPubMedCentral

Jiao, Y., Chen, R., Ke, X., Chu, K., Lu, Z., & Herskovits, E. H. (2010). Predictive models of autism spectrum disorder based on brain regional cortical thickness. NeuroImage, 50(2), 589–599. https://doi.org/10.1016/j.neuroimage.2009.12.047. CrossRefPubMed

Khundrakpam, B. S., Lewis, J. D., Kostopoulos, P., Carbonell, F., & Evans, A. C. (2017). Cortical thickness abnormalities in autism spectrum disorders through late childhood, adolescence, and adulthood: A large-scale MRI Study. Cerebral Cortex (New York,. N.Y.: 1991), 27(3), 1721–1731. https://doi.org/10.1093/cercor/bhx038. CrossRef

Kubilius, J. (2014). A framework for streamlining research workflow in neuroscience and psychology. Frontiers in Neuroinformatics. https://doi.org/10.3389/fninf.2013.00052. CrossRefPubMedPubMedCentral

Laidi, C., Boisgontier, J., Chakravarty, M. M., Hotier, S., d’Albis, M.-A., Mangin, J.-F. O., et al. (2017). Cerebellar anatomical alterations and attention to eyes in autism. Scientific Reports, 7(1), 12008. https://doi.org/10.1038/s41598-017-11883-w. CrossRefPubMedPubMedCentral

Lenroot, R. K., & Yeung, P. K. (2013). Heterogeneity within autism spectrum disorders: What have we learned from neuroimaging studies? Frontiers in Human Neuroscience, 7, 733. https://doi.org/10.3389/fnhum.2013.00733. CrossRefPubMedPubMedCentral

Loth, E., Charman, T., Mason, L., Tillmann, J., Jones, E. J. H., Wooldridge, C., et al. (2017). The EU-AIMS Longitudinal European Autism Project (LEAP): Design and methodologies to identify and validate stratification biomarkers for autism spectrum disorders. Molecular Autism, 8, 24. https://doi.org/10.1186/s13229-017-0146-8. CrossRefPubMedPubMedCentral

Mills, K. L., Goddings, A.-L., Herting, M. M., Meuwese, R., Blakemore, S.-J., Crone, E. A., et al. (2016). Structural brain development between childhood and adulthood: Convergence across four longitudinal samples. NeuroImage, 141, 273–281. https://doi.org/10.1016/j.neuroimage.2016.07.044. CrossRefPubMedPubMedCentral

Murphy, C. M., Wilson, C. E., Robertson, D. M., Ecker, C., Daly, E. M., Hammond, N., et al. (2016). Autism spectrum disorder in adults: Diagnosis, management, and health services development. Neuropsychiatric Disease and Treatment, 12, 1669–1686. https://doi.org/10.2147/NDT.S65455. CrossRefPubMedPubMedCentral

Oblak, A. L., Gibbs, T. T., & Blatt, G. J. (2010). Decreased GABA(B) receptors in the cingulate cortex and fusiform gyrus in autism. Journal of Neurochemistry, 114(5), 1414–1423. https://doi.org/10.1111/j.1471-4159.2010.06858.x. CrossRefPubMedPubMedCentral

Phan, T. V., Smeets, D., Talcott, J. B., & Vandermosten, M. (2018). Processing of structural neuroimaging data in young children: Bridging the gap between current practice and state-of-the-art methods. Developmental Cognitive Neuroscience, 33, 206–223. https://doi.org/10.1016/j.dcn.2017.08.009. CrossRefPubMed

Raznahan, A., Toro, R., Daly, E., Robertson, D., Murphy, C., Deeley, Q., et al. (2010). Cortical anatomy in autism spectrum disorder: An in vivo MRI study on the effect of age. Cerebral Cortex (New York, N.Y.: 1991) 20(6), 1332–1340. https://doi.org/10.1093/cercor/bhp198. CrossRef

Riddle, K., Cascio, C. J., & Woodward, N. D. (2017). Brain structure in autism: A voxel-based morphometry analysis of the autism brain imaging database exchange (ABIDE). Brain Imaging and Behavior, 11(2), 541–551. https://doi.org/10.1007/s11682-016-9534-5. CrossRefPubMedPubMedCentral

Rommelse, N., Buitelaar, J. K., & Hartman, C. A. (2017). Structural brain imaging correlates of ASD and ADHD across the lifespan: A hypothesis-generating review on developmental ASD–ADHD subtypes. Journal of Neural Transmission, 124(2), 259–271. https://doi.org/10.1007/s00702-016-1651-1. CrossRefPubMed

Simms, M. L., Kemper, T. L., Timbie, C. M., Bauman, M. L., & Blatt, G. J. (2009). The anterior cingulate cortex in autism: Heterogeneity of qualitative and quantitative cytoarchitectonic features suggests possible subgroups. Acta Neuropathologica, 118(5), 673–684. https://doi.org/10.1007/s00401-009-0568-2. CrossRefPubMed

Srivastava, A. K., & Schwartz, C. E. (2014). Intellectual disability and autism spectrum disorders: Causal genes and molecular mechanisms. Neuroscience and biobehavioral reviews, 46 Pt, 2, 161–174. https://doi.org/10.1016/j.neubiorev.2014.02.015. CrossRef

Valkanova, V., Rhodes, F., & Allan, C. L. (2013). Diagnosis and management of autism in adults. Practitioner, 257(1761), 2–3, 13–16.

Vijayakumar, N., Mills, K. L., Alexander-Bloch, A., Tamnes, C. K., & Whittle, S. (2018). Structural brain development: A review of methodological approaches and best practices. Developmental Cognitive Neuroscience, 33, 129–148. https://doi.org/10.1016/j.dcn.2017.11.008. CrossRefPubMed

Wallace, G. L., Dankner, N., Kenworthy, L., Giedd, J. N., & Martin, A. (2010). Age-related temporal and parietal cortical thinning in autism spectrum disorders. Brain, 133(12), 3745–3754. https://doi.org/10.1093/brain/awq279. CrossRefPubMedPubMedCentral

Wierenga, L. M., Bos, M. G. N., Schreuders, E., Vd Kamp, F., Peper, J. S., Tamnes, C. K., & Crone, E. A. (2018). Unraveling age, puberty and testosterone effects on subcortical brain development across adolescence. Psychoneuroendocrinology, 91, 105–114. https://doi.org/10.1016/j.psyneuen.2018.02.034. CrossRefPubMed

Yang, X., Si, T., Gong, Q., Qiu, L., Jia, Z., Zhou, M., et al. (2016). Brain gray matter alterations and associated demographic profiles in adults with autism spectrum disorder: A meta-analysis of voxel-based morphometry studies. The Australian and New Zealand Journal of Psychiatry, 50(8), 741–753. https://doi.org/10.1177/0004867415623858. CrossRefPubMed

Zhou, Y., Shi, L., Cui, X., Wang, S., & Luo, X. (2016). Functional connectivity of the caudal anterior cingulate cortex is decreased in autism. PLoS ONE. https://doi.org/10.1371/journal.pone.0151879. CrossRefPubMedPubMedCentral

Titel: Decreased Cortical Thickness in the Anterior Cingulate Cortex in Adults with Autism
Auteurs:: Charles Laidi
Jennifer Boisgontier
Amicie de Pierrefeu
Edouard Duchesnay
Sevan Hotier
Marc-Antoine d’Albis
Richard Delorme
Federico Bolognani
Christian Czech
Céline Bouquet
Anouck Amestoy
Julie Petit
Štefan Holiga
Juergen Dukart
Alexandru Gaman
Elie Toledano
Myriam Ly-Le Moal
Isabelle Scheid
Marion Leboyer
Josselin Houenou
Publicatiedatum: 03-12-2018
DOI: https://doi.org/10.1007/s10803-018-3807-3
Uitgeverij: Springer US
Tijdschrift: Journal of Autism and Developmental Disorders
Uitgave 4/2019
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432

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