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Journal of Autism and Developmental Disorders

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01-05-2015 | Original Paper

Cortical Variability in the Sensory-Evoked Response in Autism

Auteurs: Sarah M. Haigh, David J. Heeger, Ilan Dinstein, Nancy Minshew, Marlene Behrmann

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 5/2015

Abstract

Previous findings have shown that individuals with autism spectrum disorder (ASD) evince greater intra-individual variability (IIV) in their sensory-evoked fMRI responses compared to typical control participants. We explore the robustness of this finding with a new sample of high-functioning adults with autism. Participants were presented with visual, somatosensory and auditory stimuli in the scanner whilst they completed a one-back task. While ASD and control participants were statistically indistinguishable with respect to behavioral responses, the new ASD group exhibited greater IIV relative to controls. We also show that the IIV was equivalent across hemispheres and remained stable over the duration of the experiment. This suggests that greater cortical IIV may be a replicable characteristic of sensory systems in autism.

vorige artikel Behavioral Development and Sociodemographics of Infants and Young Children at Higher and Lower Risk for Autism Spectrum Disorders

volgende artikel Do Social Networks Differ? Comparison of the Social Networks of People with Intellectual Disabilities, People with Autism Spectrum Disorders and Other People Living in the Community

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Titel: Cortical Variability in the Sensory-Evoked Response in Autism
Auteurs: Sarah M. Haigh
David J. Heeger
Ilan Dinstein
Nancy Minshew
Marlene Behrmann
Publicatiedatum: 01-05-2015
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 5/2015
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-014-2276-6

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