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01-05-2011 | Original Paper

Controlled Evaluation of the Effects of Hyperbaric Oxygen Therapy on the Behavior of 16 Children with Autism Spectrum Disorders

Auteurs: Bryan Jepson, Doreen Granpeesheh, Jonathan Tarbox, Melissa L. Olive, Carol Stott, Scott Braud, J. Helen Yoo, Andrew Wakefield, Michael S. Allen

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 5/2011

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Abstract

Hyperbaric oxygen therapy (HBOT) has been used to treat individuals with autism. However, few studies of its effectiveness have been completed. The current study examined the effects of 40 HBOT sessions at 24% oxygen at 1.3 ATA on 11 topographies of directly observed behavior. Five replications of multiple baselines were completed across a total of 16 participants with autism spectrum disorders. No consistent effects were observed across any group or within any individual participant, demonstrating that HBOT was not an effective treatment for the participants in this study. This study represents the first relatively large-scale controlled study evaluating the effects of HBOT at the level of the individual participant, on a wide array of behaviors.
Literatuur
go back to reference Al-Waili, N. S., & Butler, G. J. (2006). Effects of hyperbaric oxygen on inflammatory response to wound and trauma: Possible mechanism of action. The Scientific World Journal, 6, 425–441. Al-Waili, N. S., & Butler, G. J. (2006). Effects of hyperbaric oxygen on inflammatory response to wound and trauma: Possible mechanism of action. The Scientific World Journal, 6, 425–441.
go back to reference Aman, M. G., & Singh, N. N. (1994). Aberrant behavior checklist–community: Supplementary manual. East Aurora, NY: Slosson Educational Publications. Aman, M. G., & Singh, N. N. (1994). Aberrant behavior checklist–community: Supplementary manual. East Aurora, NY: Slosson Educational Publications.
go back to reference American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th edn, Text Revision). Washington, DC: American Psychiatric Association. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th edn, Text Revision). Washington, DC: American Psychiatric Association.
go back to reference Anderson, D. C., Bottini, A. G., Jaqiella, W. M., Westphal, B., Ford, S., Rockswold, G. L., et al. (1991). A pilot study of hyperbaric oxygen in the treatment of human stroke. Stroke, 22, 1137–1142.PubMed Anderson, D. C., Bottini, A. G., Jaqiella, W. M., Westphal, B., Ford, S., Rockswold, G. L., et al. (1991). A pilot study of hyperbaric oxygen in the treatment of human stroke. Stroke, 22, 1137–1142.PubMed
go back to reference Ashwood, P., Anthony, A., Pellicer, A. A., Torrente, F., Walker-Smith, J. A., & Wakefield, A. J. (2003). Intestinal lymphocyte populations in children with regressive autism: Evidence for extensive mucosal immunopathology. Journal of Clinical Immunology, 23, 504–517.PubMedCrossRef Ashwood, P., Anthony, A., Pellicer, A. A., Torrente, F., Walker-Smith, J. A., & Wakefield, A. J. (2003). Intestinal lymphocyte populations in children with regressive autism: Evidence for extensive mucosal immunopathology. Journal of Clinical Immunology, 23, 504–517.PubMedCrossRef
go back to reference Ashwood, P., Anthony, A., Torrente, F., & Wakefield, A. J. (2004). Spontaneous mucosal lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms: Mucosal immune activation and reduced counter regulatory interleukin-10. Journal of Clinical Immunology, 24, 664–673.PubMedCrossRef Ashwood, P., Anthony, A., Torrente, F., & Wakefield, A. J. (2004). Spontaneous mucosal lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms: Mucosal immune activation and reduced counter regulatory interleukin-10. Journal of Clinical Immunology, 24, 664–673.PubMedCrossRef
go back to reference Balzola, F., Barbon, V., Repici, A., Rizzetto, M., Clauser, D., Gandione, M., et al. (2005). Panenteric IBD-like disease in a patient with regressive autism shown for the first time by the wireless capsule enteroscopy: Another piece in the jigsaw of this gut-brain syndrome? The American Journal of Gastroenterology, 100(4), 979–981.PubMedCrossRef Balzola, F., Barbon, V., Repici, A., Rizzetto, M., Clauser, D., Gandione, M., et al. (2005). Panenteric IBD-like disease in a patient with regressive autism shown for the first time by the wireless capsule enteroscopy: Another piece in the jigsaw of this gut-brain syndrome? The American Journal of Gastroenterology, 100(4), 979–981.PubMedCrossRef
go back to reference Bennett, M., & Heard, R. (2004). Hyperbaric oxygen therapy for multiple sclerosis. Cochrane Database of Systematic Reviews, 1, CD003057. Bennett, M., & Heard, R. (2004). Hyperbaric oxygen therapy for multiple sclerosis. Cochrane Database of Systematic Reviews, 1, CD003057.
go back to reference Bennett, M. H., Trytko, B., & Jonker, B. (2004). Hyperbaric oxygen therapy for the adjunctive treatment of traumatic brain injury. Cochrane Database Systemic Reviews, 4, CD004609. Bennett, M. H., Trytko, B., & Jonker, B. (2004). Hyperbaric oxygen therapy for the adjunctive treatment of traumatic brain injury. Cochrane Database Systemic Reviews, 4, CD004609.
go back to reference Buchman, A. L., Fife, C., Torres, C., Smith, L., & Aristizibal, J. (2001). Hyperbaric oxygen therapy for severe ulcerative colitis. Journal of Clinical Gastroenterology, 33, 337–339.PubMedCrossRef Buchman, A. L., Fife, C., Torres, C., Smith, L., & Aristizibal, J. (2001). Hyperbaric oxygen therapy for severe ulcerative colitis. Journal of Clinical Gastroenterology, 33, 337–339.PubMedCrossRef
go back to reference Cohen, I. L., & Sudhalter, V. (2005). The PDD behavior inventory. Lutz, FL: Psychological Assessment Resources, Inc. Cohen, I. L., & Sudhalter, V. (2005). The PDD behavior inventory. Lutz, FL: Psychological Assessment Resources, Inc.
go back to reference Collet, J. P., Vanasse, M., Marois, P., Amar, M., Goldberg, J., Lambert, J., et al. (2001). Hyperbaric oxygen for children with cerebral palsy: A randomised multicentre trial. HBO-CP Research Group. Lancet, 357(9256), 582–586. Collet, J. P., Vanasse, M., Marois, P., Amar, M., Goldberg, J., Lambert, J., et al. (2001). Hyperbaric oxygen for children with cerebral palsy: A randomised multicentre trial. HBO-CP Research Group. Lancet, 357(9256), 582–586.
go back to reference Crosland, K. A., Zarcone, J. R., Lindauer, S. E., Valdovinos, M. G., Zarcone, T. J., Hellings, J. A., et al. (2003). Use of functional analysis methodology in the evaluation of medication effects. Journal of Autism and Developmental Disorders, 33, 271–279.PubMedCrossRef Crosland, K. A., Zarcone, J. R., Lindauer, S. E., Valdovinos, M. G., Zarcone, T. J., Hellings, J. A., et al. (2003). Use of functional analysis methodology in the evaluation of medication effects. Journal of Autism and Developmental Disorders, 33, 271–279.PubMedCrossRef
go back to reference Furlano, R. I., Anthony, A., Day, R., Brown, A., McGarvey, L., Thomson, M. A., et al. (2001). Colonic CD8 and gamma delta T-cell infiltration with epithelial damage in children with autism. The Journal of Pediatrics, 138, 366–372.PubMedCrossRef Furlano, R. I., Anthony, A., Day, R., Brown, A., McGarvey, L., Thomson, M. A., et al. (2001). Colonic CD8 and gamma delta T-cell infiltration with epithelial damage in children with autism. The Journal of Pediatrics, 138, 366–372.PubMedCrossRef
go back to reference Gessell, L. B. (2008). Hyperbaric oxygen therapy indications. Durham, NC: Undersea and Hyperbaric Medical Society. Gessell, L. B. (2008). Hyperbaric oxygen therapy indications. Durham, NC: Undersea and Hyperbaric Medical Society.
go back to reference Gorgulu, S., Yagci, G., Kaymakcioglu, N., Ozkara, M., Kurt, B., Ozcan, A., et al. (2006). Hyperbaric oxygen enhances the efficiency of 5-aminosalicylic acid in acetic acid-induced colitis in rats. Digestive Diseases and Sciences, 51, 480–487.PubMedCrossRef Gorgulu, S., Yagci, G., Kaymakcioglu, N., Ozkara, M., Kurt, B., Ozcan, A., et al. (2006). Hyperbaric oxygen enhances the efficiency of 5-aminosalicylic acid in acetic acid-induced colitis in rats. Digestive Diseases and Sciences, 51, 480–487.PubMedCrossRef
go back to reference Granpeesheh, D., Tarbox, J., Dixon, D., Wilke, A. E., Allen, S., & Bradstreet, J. J. (2010). Randomized trial of hyperbaric oxygen therapy for children with autism. Research in Autism Spectrum Disorders, 4, 265–268. Granpeesheh, D., Tarbox, J., Dixon, D., Wilke, A. E., Allen, S., & Bradstreet, J. J. (2010). Randomized trial of hyperbaric oxygen therapy for children with autism. Research in Autism Spectrum Disorders, 4, 265–268.
go back to reference Green, V. A., Pituch, K. A., Itchon, J., Choi, A., O’Reilly, M., & Sigafoos, J. (2006). Internet survey of treatments used by parents of children with autism. Research in Developmental Disabilities, 27, 70–84.PubMedCrossRef Green, V. A., Pituch, K. A., Itchon, J., Choi, A., O’Reilly, M., & Sigafoos, J. (2006). Internet survey of treatments used by parents of children with autism. Research in Developmental Disabilities, 27, 70–84.PubMedCrossRef
go back to reference Gulec, B., Yasar, M., Yildiz, S., Oter, S., Akay, C., Deveci, S., et al. (2004). Effect of hyperbaric oxygen on experimental acute distal colitis. Physiological Research, 53, 493–499.PubMed Gulec, B., Yasar, M., Yildiz, S., Oter, S., Akay, C., Deveci, S., et al. (2004). Effect of hyperbaric oxygen on experimental acute distal colitis. Physiological Research, 53, 493–499.PubMed
go back to reference Gurbuz, A. K., Elbuken, E., Yazgan, Y., & Yildiz, S. (2003a). A different therapeutic approach in patients with severe ulcerative colitis: Hyperbaric oxygen treatment. Southern Medical Journal, 96(6), 632–633.PubMedCrossRef Gurbuz, A. K., Elbuken, E., Yazgan, Y., & Yildiz, S. (2003a). A different therapeutic approach in patients with severe ulcerative colitis: Hyperbaric oxygen treatment. Southern Medical Journal, 96(6), 632–633.PubMedCrossRef
go back to reference Gurbuz, A. K., Elbuken, E., Yazgan, Y., & Yildiz, S. (2003b). A different therapeutic approach in severe ulcerative hyperbaric oxygen treatment. Romanian Journal of Gastroenterology, 12(2), 170–171.PubMed Gurbuz, A. K., Elbuken, E., Yazgan, Y., & Yildiz, S. (2003b). A different therapeutic approach in severe ulcerative hyperbaric oxygen treatment. Romanian Journal of Gastroenterology, 12(2), 170–171.PubMed
go back to reference Guy, W. (1976). Clinical global impression. ECDEU Assessment Manual for Psychopharmacology, revised. Rockville, MD: National Institute of Mental Health. Guy, W. (1976). Clinical global impression. ECDEU Assessment Manual for Psychopharmacology, revised. Rockville, MD: National Institute of Mental Health.
go back to reference Hardy, P., Collet, J., Goldberg, J., Ducruet, T., Vanasse, M., Lambert, J., et al. (2002). Neuropsychological effects of hyperbaric oxygen therapy in cerebral palsy. Developmental Medicine and Child Neurology, 44(7), 436–446.PubMedCrossRef Hardy, P., Collet, J., Goldberg, J., Ducruet, T., Vanasse, M., Lambert, J., et al. (2002). Neuropsychological effects of hyperbaric oxygen therapy in cerebral palsy. Developmental Medicine and Child Neurology, 44(7), 436–446.PubMedCrossRef
go back to reference Helms, A. K., Whelan, H. T., & Torbey, M. T. (2005). Hyperbaric oxygen therapy of cerebral ischemia. Cerebrovascular Diseases, 20(6), 417–426.PubMedCrossRef Helms, A. K., Whelan, H. T., & Torbey, M. T. (2005). Hyperbaric oxygen therapy of cerebral ischemia. Cerebrovascular Diseases, 20(6), 417–426.PubMedCrossRef
go back to reference Horvath, K., Papadimitriou, J. C., Rabsztyn, A., Drachenberg, C., & Tildon, J. T. (1999). Gastrointestinal abnormalities in children with autistic disorder. Journal of Pediatrics, 135, 559–563.PubMedCrossRef Horvath, K., Papadimitriou, J. C., Rabsztyn, A., Drachenberg, C., & Tildon, J. T. (1999). Gastrointestinal abnormalities in children with autistic disorder. Journal of Pediatrics, 135, 559–563.PubMedCrossRef
go back to reference Iwata, B. A., Dorsey, M. F., Slifer, K. J., Bauman, K. E., Richman, G. S. (1994). Toward a functional analysis of self-injury. Journal of Applied Behavior Analysis, 27, 197–209. (Reprinted from Analysis and Intervention in Developmental Disabilities, 2, 3–20, 1982). Iwata, B. A., Dorsey, M. F., Slifer, K. J., Bauman, K. E., Richman, G. S. (1994). Toward a functional analysis of self-injury. Journal of Applied Behavior Analysis, 27, 197–209. (Reprinted from Analysis and Intervention in Developmental Disabilities, 2, 3–20, 1982).
go back to reference Jain, K. (2004). Textbook of hyperbaric medicine. Toronto: Hogrefe & Huber Pub. Jain, K. (2004). Textbook of hyperbaric medicine. Toronto: Hogrefe & Huber Pub.
go back to reference Kazdin, A. E. (1982). Single-case research designs: Methods for clinical and applied settings. New York, NY: Oxford University Press. Kazdin, A. E. (1982). Single-case research designs: Methods for clinical and applied settings. New York, NY: Oxford University Press.
go back to reference Kleijnen, J., & Knipschild, P. (1995). Hyperbaric oxygen for multiple sclerosis. Review of controlled trials. Acta Neurologica Scandinavica, 91(5), 330–334.PubMedCrossRef Kleijnen, J., & Knipschild, P. (1995). Hyperbaric oxygen for multiple sclerosis. Review of controlled trials. Acta Neurologica Scandinavica, 91(5), 330–334.PubMedCrossRef
go back to reference Kogan, M. D., et al. (2009). Prevalence of parent-reported diagnosis of autism spectrum disorder among children in the US, 2007. Pediatrics, 124, 1395–1403.PubMedCrossRef Kogan, M. D., et al. (2009). Prevalence of parent-reported diagnosis of autism spectrum disorder among children in the US, 2007. Pediatrics, 124, 1395–1403.PubMedCrossRef
go back to reference Lerman, D. C., Sansbury, T., Hovanetz, A., Wolever, E., Garcia, A., O’Brien, E., et al. (2008). Using behavior analysis to examine the outcomes of unproven therapies: An evaluation of hyperbaric oxygen therapy for children with autism. Behavior Analysis in Practice, 1, 50–58. Lerman, D. C., Sansbury, T., Hovanetz, A., Wolever, E., Garcia, A., O’Brien, E., et al. (2008). Using behavior analysis to examine the outcomes of unproven therapies: An evaluation of hyperbaric oxygen therapy for children with autism. Behavior Analysis in Practice, 1, 50–58.
go back to reference Lord, C., Rutter, M., Goode, S., Heemsbergen, J., Jordan, H., Mawhood, L., et al. (1989). Autism diagnostic observation schedule: A standardized observation of communicative and social behavior. Journal of Autism and Developmental Disorders, 19, 185–212.PubMedCrossRef Lord, C., Rutter, M., Goode, S., Heemsbergen, J., Jordan, H., Mawhood, L., et al. (1989). Autism diagnostic observation schedule: A standardized observation of communicative and social behavior. Journal of Autism and Developmental Disorders, 19, 185–212.PubMedCrossRef
go back to reference McDonagh, M., Helfand, M., Carson, S., & Russman, B. S. (2004). Hyperbaric oxygen therapy for traumatic brain injury: A systematic review of the evidence. Archives of Physical Medicine and Rehabilitation, 85, 1198–1204.PubMedCrossRef McDonagh, M., Helfand, M., Carson, S., & Russman, B. S. (2004). Hyperbaric oxygen therapy for traumatic brain injury: A systematic review of the evidence. Archives of Physical Medicine and Rehabilitation, 85, 1198–1204.PubMedCrossRef
go back to reference McDonagh, M. S., Morgan, D., Carson, S., & Russman, B. S. (2007). Systematic review of hyperbaric oxygen therapy for cerebral palsy: The state of the evidence. Developmental Medicine and Child Neurology, 49(12), 942–947.PubMedCrossRef McDonagh, M. S., Morgan, D., Carson, S., & Russman, B. S. (2007). Systematic review of hyperbaric oxygen therapy for cerebral palsy: The state of the evidence. Developmental Medicine and Child Neurology, 49(12), 942–947.PubMedCrossRef
go back to reference Nighoghossian, N., & Trouillas, P. (1995). Hyperbaric oxygen in the treatment of acute ischemic stroke. A double-blind pilot study. Stroke, 26(8), 1369–1372.PubMed Nighoghossian, N., & Trouillas, P. (1995). Hyperbaric oxygen in the treatment of acute ischemic stroke. A double-blind pilot study. Stroke, 26(8), 1369–1372.PubMed
go back to reference Nikfarjam, M., Cuthbertson, C. M., Malcontenti-Wilson, C., Muralidharen, V., Milar, I., & Christophi, C. (2007). Hyperbaric oxygen therapy reduces severity and improves survival in severe acute pancreatitis. Journal of Gastrointestinal Surgery, 11, 1008–1015.PubMedCrossRef Nikfarjam, M., Cuthbertson, C. M., Malcontenti-Wilson, C., Muralidharen, V., Milar, I., & Christophi, C. (2007). Hyperbaric oxygen therapy reduces severity and improves survival in severe acute pancreatitis. Journal of Gastrointestinal Surgery, 11, 1008–1015.PubMedCrossRef
go back to reference Pardo, C. A., Vargas, D. L., & Zimmerman, A. W. (2005). Immunity, neuroglia and neuroinflammation in autism. International Review of Psychiatry, 17, 485–495.PubMedCrossRef Pardo, C. A., Vargas, D. L., & Zimmerman, A. W. (2005). Immunity, neuroglia and neuroinflammation in autism. International Review of Psychiatry, 17, 485–495.PubMedCrossRef
go back to reference Rockswold, S. B., Rockswold, G. L., & Defillo, A. (2007). Hyperbaric oxygen in traumatic brain injury. Neurological Research, 29, 162–172.PubMedCrossRef Rockswold, S. B., Rockswold, G. L., & Defillo, A. (2007). Hyperbaric oxygen in traumatic brain injury. Neurological Research, 29, 162–172.PubMedCrossRef
go back to reference Rossignol, D. A. (2007). Hyperbaric oxygen therapy might improve certain pathophysiological findings in autism. Medical Hypotheses, 68, 1208–1227.PubMedCrossRef Rossignol, D. A. (2007). Hyperbaric oxygen therapy might improve certain pathophysiological findings in autism. Medical Hypotheses, 68, 1208–1227.PubMedCrossRef
go back to reference Rossignol, D. A., & Rossignol, L. W. (2006). Hyperbaric oxygen therapy may improve symptoms in autistic children. Medical Hypotheses, 67, 216–228.PubMedCrossRef Rossignol, D. A., & Rossignol, L. W. (2006). Hyperbaric oxygen therapy may improve symptoms in autistic children. Medical Hypotheses, 67, 216–228.PubMedCrossRef
go back to reference Rossignol, D. A., Rossignol, L. W., James, S. J., Melnyk, S., & Mumper, E. (2007). The effects of hyperbaric oxygen therapy on oxidative stress, inflammation, and symptoms in children with autism: An open-label pilot study. BMC Pediatrics, 7, 36.PubMedCrossRef Rossignol, D. A., Rossignol, L. W., James, S. J., Melnyk, S., & Mumper, E. (2007). The effects of hyperbaric oxygen therapy on oxidative stress, inflammation, and symptoms in children with autism: An open-label pilot study. BMC Pediatrics, 7, 36.PubMedCrossRef
go back to reference Rossignol, D. A., Rossignol, L. W., Smith, S., Schneider, C., Logerquist, S., Usman, A., et al. (2009). Hyperbaric treatment for children with autism: A multicenter, randomized, double-blind, controlled trial. BMC Pediatrics, 9: doi: 10.1186/1471-2431-9-21. Rossignol, D. A., Rossignol, L. W., Smith, S., Schneider, C., Logerquist, S., Usman, A., et al. (2009). Hyperbaric treatment for children with autism: A multicenter, randomized, double-blind, controlled trial. BMC Pediatrics, 9: doi: 10.​1186/​1471-2431-9-21.
go back to reference Rusyniak, D. E., Kirk, M. A., Kao, L. W., Brizendine, E. J., Welch, J. L., Cordell, W. H., et al. (2003). Hyperbaric oxygen therapy in acute ischemic stroke: Results of the hyperbaric oxygen in acute ischemic stroke trial pilot study. Stroke, 34(2), 571–574.PubMedCrossRef Rusyniak, D. E., Kirk, M. A., Kao, L. W., Brizendine, E. J., Welch, J. L., Cordell, W. H., et al. (2003). Hyperbaric oxygen therapy in acute ischemic stroke: Results of the hyperbaric oxygen in acute ischemic stroke trial pilot study. Stroke, 34(2), 571–574.PubMedCrossRef
go back to reference Ryu, Y. H., Lee, J. D., Yoon, P. H., Kim, D. I., Lee, H. B., & Shin, Y. J. (1999). Perfusion impairments in infantile autism on technetium-99 m ethyl cysteinate dimer brain single-photon emission tomography: Comparison with findings on magnetic resonance imaging. European Journal of Nuclear Medicine, 26(3), 253–259.PubMedCrossRef Ryu, Y. H., Lee, J. D., Yoon, P. H., Kim, D. I., Lee, H. B., & Shin, Y. J. (1999). Perfusion impairments in infantile autism on technetium-99 m ethyl cysteinate dimer brain single-photon emission tomography: Comparison with findings on magnetic resonance imaging. European Journal of Nuclear Medicine, 26(3), 253–259.PubMedCrossRef
go back to reference Shi, X. Y., Tang, Z. Q., Sun, D., & He, X. J. (2006). Evaluation of hyperbaric oxygen treatment of neuropsychiatric disorders following traumatic brain injury. Chinese Medical Journal (Engl), 119, 1978–1982. Shi, X. Y., Tang, Z. Q., Sun, D., & He, X. J. (2006). Evaluation of hyperbaric oxygen treatment of neuropsychiatric disorders following traumatic brain injury. Chinese Medical Journal (Engl), 119, 1978–1982.
go back to reference Singhal, A. B. (2007). A review of oxygen therapy in ischemic stroke. Neurological Research, 29(2), 173–183.PubMedCrossRef Singhal, A. B. (2007). A review of oxygen therapy in ischemic stroke. Neurological Research, 29(2), 173–183.PubMedCrossRef
go back to reference Sparrow, S., Cicchetti, D., & Balla, D. (2005). Vineland adaptive behavior scales (2nd ed.). Minneapolis, MN: Pearson Assessment. Sparrow, S., Cicchetti, D., & Balla, D. (2005). Vineland adaptive behavior scales (2nd ed.). Minneapolis, MN: Pearson Assessment.
go back to reference Starkstein, S. E., Vazquez, S., Vrancic, D., Nanclares, V., Manes, F., Piven, J., et al. (2000). SPECT findings in mentally retarded autistic individuals. The Journal of Neuropsychiatry and Clinical Neurosciences, 12(3), 370–375.PubMed Starkstein, S. E., Vazquez, S., Vrancic, D., Nanclares, V., Manes, F., Piven, J., et al. (2000). SPECT findings in mentally retarded autistic individuals. The Journal of Neuropsychiatry and Clinical Neurosciences, 12(3), 370–375.PubMed
go back to reference Torrente, F., Ashwood, P., Day, R., Machado, N., Furlando, R. I., Anthony, A., et al. (2002). Small intestinal enteropathy with epithelial IgG and complement deposition in children with regressive autism. Molecular Psychiatry, 7(4) 375–382, 334. Torrente, F., Ashwood, P., Day, R., Machado, N., Furlando, R. I., Anthony, A., et al. (2002). Small intestinal enteropathy with epithelial IgG and complement deposition in children with regressive autism. Molecular Psychiatry, 7(4) 375–382, 334.
go back to reference Vargas, D. L., Nascimbene, C., Krishnan, C., Zimmerman, A. W., & Pardo, C. A. (2005). Neuroglial activation and neuroinflammation in the brain of patients with autism. Annals of Neurology, 57, 67–81.PubMedCrossRef Vargas, D. L., Nascimbene, C., Krishnan, C., Zimmerman, A. W., & Pardo, C. A. (2005). Neuroglial activation and neuroinflammation in the brain of patients with autism. Annals of Neurology, 57, 67–81.PubMedCrossRef
go back to reference Vlodavsky, E., Palzur, E., & Soustiel, J. F. (2006). Hyperbaric oxygen therapy reduces neuroinflammation and expression of matrix metalloproteinase-9 in the rat model of traumatic brain injury. Neuropathology Applied Neurobiology, 32, 40–50.CrossRef Vlodavsky, E., Palzur, E., & Soustiel, J. F. (2006). Hyperbaric oxygen therapy reduces neuroinflammation and expression of matrix metalloproteinase-9 in the rat model of traumatic brain injury. Neuropathology Applied Neurobiology, 32, 40–50.CrossRef
go back to reference Wakefield, A. J., Anthony, A., Murch, S. H., Thomson, M., Montgomery, S. M., Davies, S., et al. (2000). Enterocolitis in children with developmental disorders. The American Journal of Gastroenterology, 95(9), 2285–2295.PubMedCrossRef Wakefield, A. J., Anthony, A., Murch, S. H., Thomson, M., Montgomery, S. M., Davies, S., et al. (2000). Enterocolitis in children with developmental disorders. The American Journal of Gastroenterology, 95(9), 2285–2295.PubMedCrossRef
go back to reference Wechsler, D. (1999). Wechsler abbreviated scale of intelligence (WASI). San Antonio, TX: Harcourt Assessment. Wechsler, D. (1999). Wechsler abbreviated scale of intelligence (WASI). San Antonio, TX: Harcourt Assessment.
go back to reference Wechsler, D. (2002). Wechsler primary and preschool scale of intelligence™–Third edition (WPPSI™-III). San Antonio, TX: Harcourt Assessment. Wechsler, D. (2002). Wechsler primary and preschool scale of intelligence™–Third edition (WPPSI™-III). San Antonio, TX: Harcourt Assessment.
go back to reference Wilcox, J., Tsuang, M. T., Ledger, E., Algeo, J., & Schnurr, T. (2002). Brain perfusion in autism varies with age. Neuropsychobiology, 46(1), 13–16.PubMedCrossRef Wilcox, J., Tsuang, M. T., Ledger, E., Algeo, J., & Schnurr, T. (2002). Brain perfusion in autism varies with age. Neuropsychobiology, 46(1), 13–16.PubMedCrossRef
go back to reference Wilson, H. D., Wilson, J. R., & Fuchs, P. N. (2006). Hyperbaric oxygen treatment decreases inflammation and mechanical hypersensitivity in an animal model of inflammatory pain. Brain Research, 1098, 126–128.PubMedCrossRef Wilson, H. D., Wilson, J. R., & Fuchs, P. N. (2006). Hyperbaric oxygen treatment decreases inflammation and mechanical hypersensitivity in an animal model of inflammatory pain. Brain Research, 1098, 126–128.PubMedCrossRef
go back to reference Wilson, H. D., Toepfer, V. E., Senapati, A. K., Wilson, J. R., & Fuchs, P. N. (2007). Hyperbaric oxygen treatment is comparable to acetylsalicylic acid treatment in an animal model of arthritis. The Journal of Pain, 8, 924–930.PubMedCrossRef Wilson, H. D., Toepfer, V. E., Senapati, A. K., Wilson, J. R., & Fuchs, P. N. (2007). Hyperbaric oxygen treatment is comparable to acetylsalicylic acid treatment in an animal model of arthritis. The Journal of Pain, 8, 924–930.PubMedCrossRef
go back to reference Zarcone, J. R., Lindauer, S. E., Morse, P. S., Crosland, K. A., Valdovinos, M. G., McKerchar, T., et al. (2004). Effects of risperidone on destructive behavior of persons with developmental disabilities: III. Functional analysis. American Journal on Mental Retardation, 109, 310–321.PubMedCrossRef Zarcone, J. R., Lindauer, S. E., Morse, P. S., Crosland, K. A., Valdovinos, M. G., McKerchar, T., et al. (2004). Effects of risperidone on destructive behavior of persons with developmental disabilities: III. Functional analysis. American Journal on Mental Retardation, 109, 310–321.PubMedCrossRef
go back to reference Zarcone, J. R., Napolitano, D., & Valdovinos, M. (2008). Measurement of problem behaviour during medication evaluations. Journal of Intellectual Disability Research, 52, 1015–1028.PubMedCrossRef Zarcone, J. R., Napolitano, D., & Valdovinos, M. (2008). Measurement of problem behaviour during medication evaluations. Journal of Intellectual Disability Research, 52, 1015–1028.PubMedCrossRef
go back to reference Zimmerman, A. W., Jyonouchi, H., Comi, A. M., Connors, S. L., Milstien, S., Varsou, A., et al. (2005). Cerebrospinal fluid and serum markers of inflammation in autism. Pediatric Neurology, 33(3), 195–201.PubMedCrossRef Zimmerman, A. W., Jyonouchi, H., Comi, A. M., Connors, S. L., Milstien, S., Varsou, A., et al. (2005). Cerebrospinal fluid and serum markers of inflammation in autism. Pediatric Neurology, 33(3), 195–201.PubMedCrossRef
Metagegevens
Titel
Controlled Evaluation of the Effects of Hyperbaric Oxygen Therapy on the Behavior of 16 Children with Autism Spectrum Disorders
Auteurs
Bryan Jepson
Doreen Granpeesheh
Jonathan Tarbox
Melissa L. Olive
Carol Stott
Scott Braud
J. Helen Yoo
Andrew Wakefield
Michael S. Allen
Publicatiedatum
01-05-2011
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 5/2011
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-010-1075-y