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15-01-2021 | Empirical Research

Concurrent and Longitudinal Associations of Sex and Race with Inflammatory Biomarkers during Adolescence

Auteurs: Naoise Mac Giollabhui, Lauren B. Alloy, Dominika Swistun, Christopher L. Coe, Lauren M. Ellman, Daniel P. Moriarity, Allison C. Stumper, Lyn Y. Abramson

Gepubliceerd in: Journal of Youth and Adolescence | Uitgave 4/2021

Abstract

Chronic, systemic inflammation is implicated in physical and mental health; little is known about whether sex and racial differences detected in adulthood are observed during adolescence or about normative changes occurring during adolescence. This longitudinal, United States-based study examined four biomarkers of systemic inflammation [C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), and IL-8) in 315 adolescents (51% female; 58% black; baseline age = 16.49 years (SD = 1.56; range: 12.14–21.28)] at three timepoints. Notable results included: general decline in inflammatory biomarkers in older adolescents, lower levels of TNF-α/IL-8 in black adolescents, elevated CRP/IL-6 in females, and especially higher levels of IL-6 in black, female adolescents. Implications are discussed, particularly the potential health implications of elevated IL-6 in black females.

vorige artikel Individual Differences in Adolescent Coping: Comparing a Community Sample and a Low-SES Sample to Understand Coping in Context

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Titel: Concurrent and Longitudinal Associations of Sex and Race with Inflammatory Biomarkers during Adolescence
Auteurs: Naoise Mac Giollabhui
Lauren B. Alloy
Dominika Swistun
Christopher L. Coe
Lauren M. Ellman
Daniel P. Moriarity
Allison C. Stumper
Lyn Y. Abramson
Publicatiedatum: 15-01-2021
Uitgeverij: Springer US
Gepubliceerd in: Journal of Youth and Adolescence / Uitgave 4/2021
Print ISSN: 0047-2891
Elektronisch ISSN: 1573-6601
DOI: https://doi.org/10.1007/s10964-020-01369-w

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