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The online version of this article (doi:10.1007/s11136-010-9761-y) contains supplementary material, which is available to authorized users.
We explored covariates of the quality of life (QOL) in non-small-cell lung cancer (NSCLC) patients and made a comparison with healthy controls.
We assessed the QOL of 220 consecutive NSCLC patients at a university hospital. The QOL data were measured by the brief version of the World Health Organization’s Quality of Life and by utility using the standard gamble method. We selected demographically matched healthy controls from the 2001 National Health Interview Survey for comparison. Multiple linear regression models were constructed to explore significant factors of QOL after controlling for covariates.
Patients with more advanced stages of NSCLC had poorer scores than did the healthy controls in the physical and psychological domains. Patients with disease duration of longer than 1 year tended to report higher physical and environment QOL than did those with NSCLC diagnosed for less than 1 year. Insight into one’s own illness was associated with a higher utility, better social support, and improved financial resources.
QOL was significantly associated with staging and duration of NSCLC. Disease insight appears to be a positive factor for operable NSCLC patients of the Taiwanese culture, which implies that clinicians should respect patient autonomy in diagnosis disclosure.
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Boyle, P., Levin, B., International Agency for Research on Cancer, & World Health Organization. (2008). World cancer report 2008. Lyon, Geneva: International Agency for Research on Cancer; Distributed by WHO Press.
Taiwan Cancer Registry. (2009). Cancer incidence and mortality rates in Taiwan. Available online at: http://crs.cph.ntu.edu.tw/main.php?Page=N2#. Accessed 3 Oct 2009.
Taiwan Cancer Registry. (2009). Survival analysis for invasive cancer. Available online at: http://tcr.cph.ntu.edu.tw/uploadimages/Sur_Lung.pdf. (in Chinese). Accessed 15 June 2010.
U.S. Food and Drug Administration, Department of Health and Human Services. (2009). Guidance for industry: patient-reported outcome measures: Use in medical product development to support labeling claims. Available online at: http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM193282.pdf. Accessed 15 June 2010.
Heshmat, S. (2001). An overview of managerial economics in the health care system. Albany, NY: Delmar Series in Health Services Administration.
Hung, Y. T. (2002). Sampling design of the National Health Interview Survey. NHIS Brief Communication No. 2.
Lin, S. H. (2002). Field collection and completeness of data in the National Health Interview Survey. NHIS Brief Communication No. 4.
The WHOQOL Group. (1998). Development of the World Health Organization WHOQOL-BREF quality of life assessment. Psychological Medicine, 28(3), 551–558. CrossRef
Yao, G., Chung, C. W., Yu, C. F., & Wang, J. D. (2002). Development and verification of validity and reliability of the WHOQOL-BREF Taiwan version. Journal of the Formosan Medical Association, 101(5), 342–351. PubMed
The WHOQOL-BREF Group. (2006). The user’s manual of the development of the WHOQOL-BREF Taiwan Version, revised 2nd Ed. Taipei, Taiwan.
Gold, M. R., Patrick, D. L., Torrance, G. W., Fryback, D. G., Hadorn, D. C., Kamlet, M. S., et al. (1996). Identifying and valuing outcomes. In M. R. Gold, J. E. Siegel, L. B. Russel, & M. C. Weinstein (Eds.), Cost-effectiveness in health and medicine (pp. 113–115). New York: Oxford University Press.
Pisters, K. M., Evans, W. K., Azzoli, C. G., Kris, M. G., Smith, C. A., Desch, C. E., et al. (2007). Cancer Care Ontario and American Society of Clinical Oncology adjuvant chemotherapy and adjuvant radiation therapy for stages I-IIIA resectable non small-cell lung cancer guideline. Journal of Clinical Oncology, 25(34), 5506–5518. PubMedCrossRef
Freund, R. J., Littell, R. C., & Spector, P. C. (1986). SAS system for linear models. Cary, NC: SAS Institute.
Watson, G. S. (1964). Smooth regression analysis. Sankhyā: The Indian Journal of Statistics, Series A, 26(4), 359–372.
Bureau of Health Promotion, Department of Health, R.O.C. (Taiwan). (2010). Cancer registry. Available online at: https://cris.bhp.doh.gov.tw/pagepub/Home.aspx?itemNo=cr.p.20 (in Chinese). Accessed 15 June 2010.
- Comparison of the quality of life between patients with non-small-cell lung cancer and healthy controls
Lukas Jyuhn-Hsiarn Lee
- Springer Netherlands