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Gepubliceerd in: Child Psychiatry & Human Development 4/2012

01-08-2012 | Original Article

Comparison of Saliva Collection Methods in Children with High-Functioning Autism Spectrum Disorders: Acceptability and Recovery of Cortisol

Auteurs: Susan K. Putnam, Christopher Lopata, Jeffery D. Fox, Marcus L. Thomeer, Jonathan D. Rodgers, Martin A. Volker, Gloria K. Lee, Erik G. Neilans, Jilynn Werth

Gepubliceerd in: Child Psychiatry & Human Development | Uitgave 4/2012

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Abstract

This study compared cortisol concentrations yielded using three saliva collection methods (passive drool, salivette, and sorbette) in both in vitro and in vivo conditions, as well as method acceptability for a sample of children (n = 39) with High Functioning Autism Spectrum Disorders. No cortisol concentration differences were observed between passive and sorbette samples obtained in vitro or in vivo. The salivette derived concentration was lower than the other two methods for the in vitro derived comparisons but did not differ from the other methods when collected in vivo. Cross-day comparison for the salivettes was also found to differ significantly, whereas the cross-day comparisons did not differ for the passive method or the sorbette method. Overall, passive drool and sorbettes were found to produce similar and stable readings of cortisol, whereas the salivette yielded unstable and variable concentrations. Ratings suggested that the children generally perceived all methods as acceptable.
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Metagegevens
Titel
Comparison of Saliva Collection Methods in Children with High-Functioning Autism Spectrum Disorders: Acceptability and Recovery of Cortisol
Auteurs
Susan K. Putnam
Christopher Lopata
Jeffery D. Fox
Marcus L. Thomeer
Jonathan D. Rodgers
Martin A. Volker
Gloria K. Lee
Erik G. Neilans
Jilynn Werth
Publicatiedatum
01-08-2012
Uitgeverij
Springer US
Gepubliceerd in
Child Psychiatry & Human Development / Uitgave 4/2012
Print ISSN: 0009-398X
Elektronisch ISSN: 1573-3327
DOI
https://doi.org/10.1007/s10578-012-0284-3