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Lung volume reduction surgery (LVRS) has been shown to improve lung function, but also improve the overall quality of life (QOL). The aim of this study is to compare two QOL questionnaires-EuroQol Questionnaire (EQ-5D-3L) and 36-item Short Form Health Survey (SF-36) in patients post-LVRS.
All patients undergoing LVRS for severe chronic obstructive pulmonary disease (COPD) at a single center of excellence were analyzed (n = 94). Baseline demographic and clinical outcomes were characterized. Both EQ-5D-3L and SF-36 questionnaires were administered to all patients at baseline (n = 94) and at the end of 1 year (n = 89) post-surgery. SF-36 was converted to Short Form six-dimensions (SF-6D) using standard algorithm. Correlation, discrimination, responsiveness and differences across the two questionnaires were examined.
The mean age of patients enrolled in the cohort was 66 years. There was significant increase in forced expiratory volume (FEV1, 43%), forced vital capacity (FVC 46%), diffusion capacity (DLCO 15%), 6 min walk distance test (6MWD 21%) and a significant decrease in residual volume (RV 23%) at the end of 1-year follow-up. The overall mean utility index significantly improved for both SF-6D and EQ-5D-3L questionnaires at the end of follow-up (p = 0.0001). However, the magnitude of percentage increase was higher with EQ-5D-3L compared to SF-6D (32% vs. 13%). Stronger correlations confirmed convergent validity at the end of 1-year follow-up between similar domains. Both questionnaires failed to discriminate between different levels of disease severity post-LVRS in patients with severe COPD.
Both questionnaires responded similarly in patients with COPD post-LVRS. Combining results from QOL questionnaire(s) along with symptoms of disease and history of exacerbation may be a possible solution for identifying disease severity in old and sick patients unwilling/unable to come to hospital for a pulmonary function test post-LVRS.
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Centers for Disease Control and Prevention. (2012). Chronic obstructive pulmonary disease among adults–United States, 2011. Morbidity and Mortality Weekly Report, 61(46), 938–943.
Centers for Diseasr Control and Prevention. (2017). Chronic obstructive pulmonary disease. Retrieved May 31, 2018, from https://www.cdc.gov/copd/index.html#6.
Wacker, M. E., Jorres, R. A., Karch, A., Wilke, S., Heinrich, J., Karrasch, S., Koch, A., Schulz, H., Watz, H., Leidl, R., Vogelmeier, C., Holle, R., & Consortium, C. (2016). Assessing health-related quality of life in COPD: Comparing generic and disease-specific instruments with focus on comorbidities. BMC Pulmonary Medicine, 16(1), 70. CrossRefPubMedPubMedCentral
Goldstein, R. S., Todd, T. R., Guyatt, G., Keshavjee, S., Dolmage, T. E., van Rooy, S., Krip, B., Maltais, F., LeBlanc, P., Pakhale, S., & Waddell, T. K. (2003). Influence of lung volume reduction surgery (LVRS) on health related quality of life in patients with chronic obstructive pulmonary disease. Thorax, 58(5), 405–410. CrossRefPubMedPubMedCentral
Huang, W., Wang, W. R., Deng, B., Tan, Y. Q., Jiang, G. Y., Zhou, H. J., & He, Y. (2011). Several clinical interests regarding lung volume reduction surgery for severe emphysema: Meta-analysis and systematic review of randomized controlled trials. Journal of Cardiothoracic Surgery, 6, 148. CrossRefPubMedPubMedCentral
Beer, T. M., Miller, K., Tombal, B., Cella, D., Phung, D., Holmstrom, S., Ivanescu, C., Skaltsa, K., & Naidoo, S. (2017). The association between health-related quality-of-life scores and clinical outcomes in metastatic castration-resistant prostate cancer patients: Exploratory analyses of AFFIRM and PREVAIL studies. European Journal of Cancer, 87, 21–29. CrossRefPubMed
Vickers, M. M., Lee, C., Tu, D., Wheatley-Price, P., Parulekar, W., Brundage, M. D., Moore, M. J., Au, H., O’Callaghan, C. J., Jonker, D. J., Ringash, J., & Goldstein, D. (2016). Significance of baseline and change in quality of life scores in predicting clinical outcomes in an international phase III trial of advanced pancreatic cancer: NCIC CTG PA.3. Pancreatology, 16(6), 1106–1112. CrossRefPubMed
McCrone, P., Patel, A., Knapp, M., Schene, A., Koeter, M., Amaddeo, F., Ruggeri, M., Giessler, A., Puschner, B., & Thornicroft, G. (2009). A comparison of SF-6D and EQ-5D utility scores in a study of patients with schizophrenia. The Journal of Mental Health Policy and Economics, 12(1), 27–31. PubMed
Brooks, R. (1996). EuroQol: The current state of play. Health Policy, 37(1), 53–72. CrossRef
User’s Manual for the Medical Outcomes Study (MOS). (1995). Core measures of health-related quality of life. Santa Monica: RAND Corporation.
Global Initiative for COPD. (2017). Pocket guide to COPD diagnosis, management, and prevention: A guide for health care professionals.
DeLong, E. R., DeLong, D. M., & Clarke-Pearson, D. L. (1988). Comparing the areas under two or more correlated receiver operating characteristic curves: A nonparametric approach. Biometrics, 44(3), 837–845. CrossRef
Kularatna, S., Byrnes, J., Chan, Y. K., Ski, C. F., Carrington, M., Thompson, D., Stewart, S., & Scuffham, P. A. (2017). Comparison of the EQ-5D-3L and the SF-6D (SF-12) contemporaneous utility scores in patients with cardiovascular disease. Quality of Life Research, 26(12), 3399–3408. CrossRefPubMed
Brazier, J., Rowen, D., Tsuchiya, A., Yang, Y., & Young, T. A. (2011). The impact of adding an extra dimension to a preference-based measure. Social Science & Medicine, 73(2), 245–253. CrossRef
Payakachat, N., Ali, M. M., & Tilford, J. M. (2015). Can The EQ-5D detect meaningful change? A Systematic Review. Pharmacoeconomics, 33(11), 1137–1154. PubMed
- Comparison between the EQ-5D-3L and the SF-6D quality of life (QOL) questionnaires in patients with chronic obstructive pulmonary disease (COPD) undergoing lung volume reduction surgery (LVRS)
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