Skip to main content
main-content
Top

Tip

Swipe om te navigeren naar een ander artikel

Gepubliceerd in: Quality of Life Research 7/2013

01-09-2013

Comparing the performance of the standard EQ-5D 3L with the new version EQ-5D 5L in patients with chronic hepatic diseases

Auteurs: Luciana Scalone, Roberta Ciampichini, Stefano Fagiuoli, Ivan Gardini, Francesco Fusco, Laura Gaeta, Anna Del Prete, Giancarlo Cesana, Lorenzo G. Mantovani

Gepubliceerd in: Quality of Life Research | Uitgave 7/2013

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Purpose

To assess the performance of the EQ-5D-5L version compared with the standard EQ-5D-3L in a clinical setting targeted at patients with chronic hepatic diseases (CHDs).

Methods

We introduced the 5L descriptive system into a cost-of-illness study involving patients with different CHDs. The patients completed a questionnaire including the two versions of the EQ-5D, together with other questions related to their condition. We tested the feasibility, the level of inconsistency, the redistribution properties among consistent responses, the ceiling effect, the discriminative power, and the convergent validity of the 5L compared with the 3L system.

Results

A total of 1,088 valid patients were recruited: 62 % male, 19–89 (median = 59) years old. Patients had chronic hepatitis from HCV (31.8 %) or HBV infections (29.3 %) or other causes (7.8 %), 20.4 % had cirrhosis, 11.9 % underwent liver transplantation, and 7.8 % had hepatic carcinoma. Less than 1 % of EQ-5D-5L were returned blank, and 1.6 % or less of missing values were calculated on the dimensions of the partially completed questionnaires. The proportion and weight of inconsistent responses (i.e., 3L responses that were at least two levels away from the 5L responses) was 2.9 % and 1.2 on average, respectively. Regarding redistribution, 57–65 % of the patients answering level 2 with the 3L version redistributed their responses to levels 2 or 4 with the 5L version. A relative 7 % reduction of the ceiling effect was found. Furthermore, the absolute informativity increased but the relative informativity slightly decreased in every domain, and the convergent validity with the VAS improved.

Conclusions

In a clinical setting involving CHD patients, the EQ-5D-5L was shown to be feasible and with promising levels of performance. Our findings suggest that the 5L performs better in at least some of the properties analyzed, and encourage further research to also test other psychometric properties of this new version of the EQ-5D.
Literatuur
1.
go back to reference Rabin, R., & de Charro, F. (2001). EQ-5D: A measure of health status from the EuroQol Group. Annals of Medicine, 33, 337–343. PubMedCrossRef Rabin, R., & de Charro, F. (2001). EQ-5D: A measure of health status from the EuroQol Group. Annals of Medicine, 33, 337–343. PubMedCrossRef
2.
go back to reference Ong, S. C., Mak, B., Aung, M. O., Li, S. C., & Lim, S. G. (2008). Health-related quality of life in chronic hepatitis B patients. Hepatology, 47(4), 1108–1117. PubMedCrossRef Ong, S. C., Mak, B., Aung, M. O., Li, S. C., & Lim, S. G. (2008). Health-related quality of life in chronic hepatitis B patients. Hepatology, 47(4), 1108–1117. PubMedCrossRef
3.
go back to reference McLernon, D. J., Dillon, J., & Donnan, P. T. (2008). Health-state utilities in liver disease: A systematic review. Medical Decision Making, 28(4), 582–592. PubMedCrossRef McLernon, D. J., Dillon, J., & Donnan, P. T. (2008). Health-state utilities in liver disease: A systematic review. Medical Decision Making, 28(4), 582–592. PubMedCrossRef
4.
go back to reference Russel, R. T., Feurer, I. D., Wisawatapnimit, P., & Pinson, C. W. (2009). The validity of the EQ-5D US preference weights in liver transplant candidates and recipients. Liver Transplantation, 15(1), 88–95. CrossRef Russel, R. T., Feurer, I. D., Wisawatapnimit, P., & Pinson, C. W. (2009). The validity of the EQ-5D US preference weights in liver transplant candidates and recipients. Liver Transplantation, 15(1), 88–95. CrossRef
5.
go back to reference Bjornsson, E., Verbaan, H., Oksanen, A., Fryden, A., Johansson, J., Friberg, S., et al. (2009). Health-related quality of life in patients with different stages of liver disease induced by hepatitis C. Scandinavian Journal of Gastroenterology, 44(7), 878–887. PubMedCrossRef Bjornsson, E., Verbaan, H., Oksanen, A., Fryden, A., Johansson, J., Friberg, S., et al. (2009). Health-related quality of life in patients with different stages of liver disease induced by hepatitis C. Scandinavian Journal of Gastroenterology, 44(7), 878–887. PubMedCrossRef
6.
go back to reference Pickard, A. S., De Leon, M. C., Kohlmann, T., Cella, D., & Rosenbloom, S. (2007). Psychometric comparison of the standard EQ-5D to a 5 level version in cancer patients. Medical Care, 45(3), 259–263. PubMedCrossRef Pickard, A. S., De Leon, M. C., Kohlmann, T., Cella, D., & Rosenbloom, S. (2007). Psychometric comparison of the standard EQ-5D to a 5 level version in cancer patients. Medical Care, 45(3), 259–263. PubMedCrossRef
7.
go back to reference Pickard, A. S., Kohlmann, T., Janssen, M. F., Bonsel, G., Rosenbloom, S., & Cella, D. (2007). Evaluating equivalency between response systems. Application of the Rasch model to a 3-level and 5-level EQ-5D. Medical Care, 45(9), 812–819. PubMedCrossRef Pickard, A. S., Kohlmann, T., Janssen, M. F., Bonsel, G., Rosenbloom, S., & Cella, D. (2007). Evaluating equivalency between response systems. Application of the Rasch model to a 3-level and 5-level EQ-5D. Medical Care, 45(9), 812–819. PubMedCrossRef
8.
go back to reference Janssen, M. F., Birnie, E., Haagsma, J. A., & Bonsel, G. J. (2008). Comparing the standard EQ-5D three-level system with a five-level version. Value in Health, 11(2), 275–284. PubMedCrossRef Janssen, M. F., Birnie, E., Haagsma, J. A., & Bonsel, G. J. (2008). Comparing the standard EQ-5D three-level system with a five-level version. Value in Health, 11(2), 275–284. PubMedCrossRef
9.
go back to reference Janssen, M. F., Birnie, E., & Bonsel, G. J. (2008). Quantification of the level descriptors for the standard EQ-5D three-level system and five-level version according to two methods. Quality of Life Research, 15, 463–473. CrossRef Janssen, M. F., Birnie, E., & Bonsel, G. J. (2008). Quantification of the level descriptors for the standard EQ-5D three-level system and five-level version according to two methods. Quality of Life Research, 15, 463–473. CrossRef
10.
go back to reference Herdman, M., Gudex, C., Lloyd, A., Janssen, M., Kind, P., Parkin, D., et al. (2011). Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L). Quality of Life Research, 20(10), 1727–1736. PubMedCrossRef Herdman, M., Gudex, C., Lloyd, A., Janssen, M., Kind, P., Parkin, D., et al. (2011). Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L). Quality of Life Research, 20(10), 1727–1736. PubMedCrossRef
11.
go back to reference Kim, S. H., Kim, H. J., Lee, S. I., Jo, M. W. (2011). Comparing the psychometric properties of the EQ-5D-3L and EQ-5D-5L in cancer patients in Korea. Quality of Life Research published online 23 September 2011. Kim, S. H., Kim, H. J., Lee, S. I., Jo, M. W. (2011). Comparing the psychometric properties of the EQ-5D-3L and EQ-5D-5L in cancer patients in Korea. Quality of Life Research published online 23 September 2011.
12.
go back to reference Ciampichini, R., Scalone, L., Gardini, I., Gaeta, L., Del Prete, A., Fusco, F., et al. (2011). Comparison of health-related quality of life between hepatitis, cirrhosis, liver transplantation and hepatic carcinoma: results of the COME study. Value in Health, 14(PGI30), 174. Ciampichini, R., Scalone, L., Gardini, I., Gaeta, L., Del Prete, A., Fusco, F., et al. (2011). Comparison of health-related quality of life between hepatitis, cirrhosis, liver transplantation and hepatic carcinoma: results of the COME study. Value in Health, 14(PGI30), 174.
13.
go back to reference Fusco, F., Scalone, L., Ciampichini, R., Fagioli, S., Gardini, I., Gaeta, L., et al. (2011). Comparison of treatment and indirect costs between hepatitis, cirrhosis, liver transplantation and hepatic carcinoma: Results of the COME study. Value In Health, 14(PGI16), 171. Fusco, F., Scalone, L., Ciampichini, R., Fagioli, S., Gardini, I., Gaeta, L., et al. (2011). Comparison of treatment and indirect costs between hepatitis, cirrhosis, liver transplantation and hepatic carcinoma: Results of the COME study. Value In Health, 14(PGI16), 171.
14.
go back to reference World Medical Association (WMA) Declaration of Helsinki. Adopted by the 18th World Medical Assembly, Helsinki, Finland, June 1964, amended by the 29th World Medical Assembly, Tokyo, Japan, October 1975, the 35th World Medical Assembly, Venice, Italy, October 1983, and the 41st World Medical Assembly, Hong Kong, September 1989. World Medical Association (WMA) Declaration of Helsinki. Adopted by the 18th World Medical Assembly, Helsinki, Finland, June 1964, amended by the 29th World Medical Assembly, Tokyo, Japan, October 1975, the 35th World Medical Assembly, Venice, Italy, October 1983, and the 41st World Medical Assembly, Hong Kong, September 1989.
15.
go back to reference Herdman, M., Fox-Rushby, J., Rabin, R., Badia, X., & Selai, C. (2003). Producing other language versions of the EQ-5D. In R. Brooks, R. Rabin, & F. de Charro (Eds.), The measurement and valuation of health status using EQ-5D: A European perspective. Dordrecht: Kluwer Academic Publishers. Herdman, M., Fox-Rushby, J., Rabin, R., Badia, X., & Selai, C. (2003). Producing other language versions of the EQ-5D. In R. Brooks, R. Rabin, & F. de Charro (Eds.), The measurement and valuation of health status using EQ-5D: A European perspective. Dordrecht: Kluwer Academic Publishers.
16.
go back to reference Badia, X., Montserrat, R., Herdman, M., & Kind, P. (2001). A comparison of United Kingdom and Spanish general population time trade-off values for EQ-5D health states. Medical Decision Making, 21, 7–16. PubMedCrossRef Badia, X., Montserrat, R., Herdman, M., & Kind, P. (2001). A comparison of United Kingdom and Spanish general population time trade-off values for EQ-5D health states. Medical Decision Making, 21, 7–16. PubMedCrossRef
17.
go back to reference van Hout, B., Janssen, M. F., Feng, Y., Kohlmann, T., Busschbach, J., Golicki, D., et al. (2012). Interim scoring for the EQ-5D-5L: Mapping the EQ-5D-5L to EQ-5D-3L value sets. Value Health, 15(5), 708–715. PubMedCrossRef van Hout, B., Janssen, M. F., Feng, Y., Kohlmann, T., Busschbach, J., Golicki, D., et al. (2012). Interim scoring for the EQ-5D-5L: Mapping the EQ-5D-5L to EQ-5D-3L value sets. Value Health, 15(5), 708–715. PubMedCrossRef
18.
go back to reference Bas Janssen, M. F., Birnie, E., & Bonsel, G. J. (2007). Evaluating the discriminatory power of EQ-5D, HUI2 and HUI3 in a US general population survey using Shannon’s indices. Quality of Life Research, 16(5), 895–904. PubMedCrossRef Bas Janssen, M. F., Birnie, E., & Bonsel, G. J. (2007). Evaluating the discriminatory power of EQ-5D, HUI2 and HUI3 in a US general population survey using Shannon’s indices. Quality of Life Research, 16(5), 895–904. PubMedCrossRef
19.
go back to reference Polinder, S., Haagsma, J. A., Bonsel, G., et al. (2010). The measurement of long-term health-related quality of life after injury: Comparison of EQ-5D and the health utilities index. Injury Prevention, 16(3), 147–153. PubMedCrossRef Polinder, S., Haagsma, J. A., Bonsel, G., et al. (2010). The measurement of long-term health-related quality of life after injury: Comparison of EQ-5D and the health utilities index. Injury Prevention, 16(3), 147–153. PubMedCrossRef
20.
go back to reference Shannon, C. E., & Weaver, W. (1949). The mathematical theory of communication. Urbana: University of Illinois Press. Shannon, C. E., & Weaver, W. (1949). The mathematical theory of communication. Urbana: University of Illinois Press.
21.
go back to reference Juniper, E. F., Guyatt, G. H., & Jaeshke, R. (1996). How to develop and validate a new health-related quality of life instrument. In B. Spilker (Ed.), Quality of life and pharmacoeconomics in clinical trials (pp. 49–56). Philadelphia, PA: Lippincott-Raven Publishers. Juniper, E. F., Guyatt, G. H., & Jaeshke, R. (1996). How to develop and validate a new health-related quality of life instrument. In B. Spilker (Ed.), Quality of life and pharmacoeconomics in clinical trials (pp. 49–56). Philadelphia, PA: Lippincott-Raven Publishers.
22.
go back to reference Unal, G., de Boer, J. B., Borsboom, G. J., Brouwer, J. T., Essink-Bot, M., & de Man, R. A. (2001). A psychometric comparison of health-related quality of life measures in chronic liver disease. Journal of Clinical Epidemiology, 54(6), 587–596. PubMedCrossRef Unal, G., de Boer, J. B., Borsboom, G. J., Brouwer, J. T., Essink-Bot, M., & de Man, R. A. (2001). A psychometric comparison of health-related quality of life measures in chronic liver disease. Journal of Clinical Epidemiology, 54(6), 587–596. PubMedCrossRef
23.
go back to reference van der Plas, S. M., Hansen, B. E., de Boer, J. B., Stijnen, T., Passchier, J., de Man, R. A., et al. (2003). Generic and disease-specific health-related quality of life in non-cirrhotic, cirrhotic and transplanted liver patients: a cross-sectional study. BMC Gastroenterology, 17(3), 33. CrossRef van der Plas, S. M., Hansen, B. E., de Boer, J. B., Stijnen, T., Passchier, J., de Man, R. A., et al. (2003). Generic and disease-specific health-related quality of life in non-cirrhotic, cirrhotic and transplanted liver patients: a cross-sectional study. BMC Gastroenterology, 17(3), 33. CrossRef
24.
go back to reference Casanovas Taltavull, T., Jané Cabré, L., Herdman, M., Casado Collado, A., Pubill, B. P., & Fabregat Prous, J. (2007). Validation of the Spanish version of the liver disease quality of life instrument among candidates for liver transplant. Transplantation Proceedings, 39(7), 2274–2277. PubMedCrossRef Casanovas Taltavull, T., Jané Cabré, L., Herdman, M., Casado Collado, A., Pubill, B. P., & Fabregat Prous, J. (2007). Validation of the Spanish version of the liver disease quality of life instrument among candidates for liver transplant. Transplantation Proceedings, 39(7), 2274–2277. PubMedCrossRef
25.
go back to reference Casanovas, T., Jané, L., Herdman, M., Casado, A., Garcia, B., Prat, B., et al. (2010). Assessing outcomes in liver disease patients: Reliability and validity of the Spanish version of the Liver Disease Quality of Life Questionnaire (LDQOL 1.0). Value Health, 13, 455–462. PubMedCrossRef Casanovas, T., Jané, L., Herdman, M., Casado, A., Garcia, B., Prat, B., et al. (2010). Assessing outcomes in liver disease patients: Reliability and validity of the Spanish version of the Liver Disease Quality of Life Questionnaire (LDQOL 1.0). Value Health, 13, 455–462. PubMedCrossRef
Metagegevens
Titel
Comparing the performance of the standard EQ-5D 3L with the new version EQ-5D 5L in patients with chronic hepatic diseases
Auteurs
Luciana Scalone
Roberta Ciampichini
Stefano Fagiuoli
Ivan Gardini
Francesco Fusco
Laura Gaeta
Anna Del Prete
Giancarlo Cesana
Lorenzo G. Mantovani
Publicatiedatum
01-09-2013
Uitgeverij
Springer Netherlands
Gepubliceerd in
Quality of Life Research / Uitgave 7/2013
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-012-0318-0