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Gepubliceerd in: Journal of Abnormal Child Psychology 3/2017

01-07-2016

Comparing the CASI-4R and the PGBI-10 M for Differentiating Bipolar Spectrum Disorders from Other Outpatient Diagnoses in Youth

Auteurs: Mian-Li Ong, Eric A. Youngstrom, Jesselyn Jia-Xin Chua, Tate F. Halverson, Sarah M. Horwitz, Amy Storfer-Isser, Thomas W. Frazier, Mary A. Fristad, L. Eugene Arnold, Mary L. Phillips, Boris Birmaher, Robert A. Kowatch, Robert L. Findling, the LAMS Group

Gepubliceerd in: Research on Child and Adolescent Psychopathology | Uitgave 3/2017

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Abstract

We compared 2 rating scales with different manic symptom items on diagnostic accuracy for detecting pediatric bipolar spectrum disorder (BPSDs) in outpatient mental health clinics. Participants were 681 parents/guardians of eligible children (465 male, mean age = 9.34) who completed the Parent General Behavior Inventory-10-item Mania (PGBI-10 M) and mania subscale of the Child and Adolescent Symptom Inventory-Revised (CASI-4R). Diagnoses were based on KSADS interviews with parent and youth. Receiver operating characteristic (ROC) analyses and diagnostic likelihood ratios (DLRs) determined discriminative validity and provided clinical utility, respectively. Logistic regressions tested for incremental validity in the CASI-4R mania subscale and PGBI-10 M in predicting youth BPSD status above and beyond demographic and common diagnostic comorbidities. Both CASI-4R and PGBI-10 M scales significantly distinguished BPSD (N = 160) from other disorders (CASI-4R: Area under curve (AUC) = .80, p < 0.0005; PGBI-10 M: AUC = 0.79, p < 0.0005) even though scale items differed. Both scales performed equally well in differentiating BPSDs (Venkatraman test p > 0.05). Diagnostic likelihood ratios indicated low scores on either scale (CASI: 0–5; PGBI-10 M: 0–6) cut BPSD odds to 1/5 of those with high scores (CASI DLR- = 0.17; PGBI-10 M DLR- = 0.18). High scores on either scale (CASI: 14+; PGBI-10 M: 20+) increased BPSD odds about fourfold (CASI DLR+ = 4.53; PGBI-10 M DLR+ = 3.97). Logistic regressions indicated the CASI-4R mania subscale and PGBI-10 M each provided incremental validity in predicting youth BPSD status. The CASI-4R is at least as valid as the PGBI-10 M to help identify BPSDs, and can be considered as part of an assessment battery to screen for pediatric BPSDs.

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Metagegevens
Titel
Comparing the CASI-4R and the PGBI-10 M for Differentiating Bipolar Spectrum Disorders from Other Outpatient Diagnoses in Youth
Auteurs
Mian-Li Ong
Eric A. Youngstrom
Jesselyn Jia-Xin Chua
Tate F. Halverson
Sarah M. Horwitz
Amy Storfer-Isser
Thomas W. Frazier
Mary A. Fristad
L. Eugene Arnold
Mary L. Phillips
Boris Birmaher
Robert A. Kowatch
Robert L. Findling
the LAMS Group
Publicatiedatum
01-07-2016
Uitgeverij
Springer US
Gepubliceerd in
Research on Child and Adolescent Psychopathology / Uitgave 3/2017
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI
https://doi.org/10.1007/s10802-016-0182-4