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Gepubliceerd in: Journal of Autism and Developmental Disorders 3/2015

01-03-2015 | Original Paper

Cognitive Set Shifting Deficits and Their Relationship to Repetitive Behaviors in Autism Spectrum Disorder

Auteurs: Haylie L. Miller, Michael E. Ragozzino, Edwin H. Cook, John A. Sweeney, Matthew W. Mosconi

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 3/2015

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Abstract

The neurocognitive impairments associated with restricted and repetitive behaviors (RRBs) in autism spectrum disorder (ASD) are not yet clear. Prior studies indicate that individuals with ASD show reduced cognitive flexibility, which could reflect difficulty shifting from a previously learned response pattern or a failure to maintain a new response set. We examined different error types on a test of set-shifting completed by 60 individuals with ASD and 55 age- and nonverbal IQ-matched controls. Individuals with ASD were able to initially shift sets, but they exhibited difficulty maintaining new response sets. Difficulty with set maintenance was related to increased severity of RRBs. General difficulty maintaining new response sets and a heightened tendency to revert to old preferences may contribute to RRBs.
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Literatuur
go back to reference Agam, Y., Joseph, R. M., Barton, J. J. S., & Manoach, D. S. (2010). Reduced cognitive control of response inhibition by the anterior cingulate cortex in autism spectrum disorders. NeuroImage, 52, 336–347.CrossRefPubMedCentralPubMed Agam, Y., Joseph, R. M., Barton, J. J. S., & Manoach, D. S. (2010). Reduced cognitive control of response inhibition by the anterior cingulate cortex in autism spectrum disorders. NeuroImage, 52, 336–347.CrossRefPubMedCentralPubMed
go back to reference American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed., text rev.). Washington, DC: American Psychiatric Publishing. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed., text rev.). Washington, DC: American Psychiatric Publishing.
go back to reference American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Arlington, VA: American Psychiatric Publishing.CrossRef American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Arlington, VA: American Psychiatric Publishing.CrossRef
go back to reference Amodeo, D. A., Jones, J. H., Sweeney, J. A., & Ragozzino, M. E. (2014). Risperidone and the 5-HT2a receptor antagonist M100907 improve probabilistic reversal learning in BTBR T + tf/J mice. Autism Research, online advance publication. doi: 10.1002/aur1395. Amodeo, D. A., Jones, J. H., Sweeney, J. A., & Ragozzino, M. E. (2014). Risperidone and the 5-HT2a receptor antagonist M100907 improve probabilistic reversal learning in BTBR T + tf/J mice. Autism Research, online advance publication. doi: 10.​1002/​aur1395.
go back to reference Baker, P. M., Thompson, J. L., Sweeney, J. A., & Ragozzino, M. E. (2011). Differential effects of 5-HT2A and 5-HT2C receptor blockade on strategy-switching. Behavioural Brain Research, 219(1), 123–131.CrossRefPubMedCentralPubMed Baker, P. M., Thompson, J. L., Sweeney, J. A., & Ragozzino, M. E. (2011). Differential effects of 5-HT2A and 5-HT2C receptor blockade on strategy-switching. Behavioural Brain Research, 219(1), 123–131.CrossRefPubMedCentralPubMed
go back to reference Barceló, F., & Knight, R. T. (2002). Both random and perseverative errors underlie WCST deficits in prefrontal patients. Neuropsychologia, 40, 349–356.CrossRefPubMed Barceló, F., & Knight, R. T. (2002). Both random and perseverative errors underlie WCST deficits in prefrontal patients. Neuropsychologia, 40, 349–356.CrossRefPubMed
go back to reference Bishop, D. V. M., & Norbury, C. F. (2005). Executive functions in children with communication impairments, in relation to autistic symptomatology. Autism, 9(1), 7–43.CrossRefPubMed Bishop, D. V. M., & Norbury, C. F. (2005). Executive functions in children with communication impairments, in relation to autistic symptomatology. Autism, 9(1), 7–43.CrossRefPubMed
go back to reference Bissonette, G. B., Martins, G. J., Franz, T. M., Harper, E. S., Schoenbaum, G., & Powell, E. M. (2008). Double dissociation of the effects of medial and orbital prefrontal cortical lesions on attentional and affective shifts in mice. Journal of Neuroscience, 28(44), 11124–11130.CrossRefPubMedCentralPubMed Bissonette, G. B., Martins, G. J., Franz, T. M., Harper, E. S., Schoenbaum, G., & Powell, E. M. (2008). Double dissociation of the effects of medial and orbital prefrontal cortical lesions on attentional and affective shifts in mice. Journal of Neuroscience, 28(44), 11124–11130.CrossRefPubMedCentralPubMed
go back to reference Brown, H. D., Amodeo, D. A., Sweeney, J. A., & Ragozzino, M. E. (2012). The selective serotonin reuptake inhibitor, escitalopram, enhances inhibition of prepotent responding and spatial reversal learning. Journal of Psychopharmacology, 26(11), 1443–1455.CrossRefPubMedCentralPubMed Brown, H. D., Amodeo, D. A., Sweeney, J. A., & Ragozzino, M. E. (2012). The selective serotonin reuptake inhibitor, escitalopram, enhances inhibition of prepotent responding and spatial reversal learning. Journal of Psychopharmacology, 26(11), 1443–1455.CrossRefPubMedCentralPubMed
go back to reference Brown, H. D., Baker, P. M., & Ragozzino, M. E. (2010). The parafascicular thalamic nucleus concomitantly influences behavioral flexibility and dorsomedial striatal acetylcholine output in rats. Journal of Neuroscience, 30(43), 14390–14398.CrossRefPubMedCentralPubMed Brown, H. D., Baker, P. M., & Ragozzino, M. E. (2010). The parafascicular thalamic nucleus concomitantly influences behavioral flexibility and dorsomedial striatal acetylcholine output in rats. Journal of Neuroscience, 30(43), 14390–14398.CrossRefPubMedCentralPubMed
go back to reference Cody, H., Pelphrey, K., & Piven, J. (2002). Structural and functional magnetic resonance imaging of autism. International Journal of Developmental Neuroscience, 20(3–5), 421–438.CrossRefPubMed Cody, H., Pelphrey, K., & Piven, J. (2002). Structural and functional magnetic resonance imaging of autism. International Journal of Developmental Neuroscience, 20(3–5), 421–438.CrossRefPubMed
go back to reference Cody-Hazlett, H., Poe, M. D., Gerig, G., Gimpel-Smith, R., & Piven, J. (2006). Cortical gray and white brain tissue volume in adolescents and adults with autsm. Biological Psychiatry, 59, 1–6.CrossRef Cody-Hazlett, H., Poe, M. D., Gerig, G., Gimpel-Smith, R., & Piven, J. (2006). Cortical gray and white brain tissue volume in adolescents and adults with autsm. Biological Psychiatry, 59, 1–6.CrossRef
go back to reference Corbett, B. A., Constantine, L. J., Hendren, R., Rocke, D., & Ozonoff, S. (2009). Examining executive functioning in children with autism spectrum disorder, attention deficit hyperactivity disorder and typical development. Psychiatry Research, 166(2–3), 201–222. Corbett, B. A., Constantine, L. J., Hendren, R., Rocke, D., & Ozonoff, S. (2009). Examining executive functioning in children with autism spectrum disorder, attention deficit hyperactivity disorder and typical development. Psychiatry Research, 166(2–3), 201–222.
go back to reference Cuccaro, M. L., Shao, Y., Grubber, J., Slifer, M., Wolpert, C. M., Donnelly, S. L., et al. (2003). Factor analysis of restricted and repetitive behaviors in autism using the Autism Diagnostic Interview-R. Child Psychiatry and Human Development, 34(1), 3–17.CrossRefPubMed Cuccaro, M. L., Shao, Y., Grubber, J., Slifer, M., Wolpert, C. M., Donnelly, S. L., et al. (2003). Factor analysis of restricted and repetitive behaviors in autism using the Autism Diagnostic Interview-R. Child Psychiatry and Human Development, 34(1), 3–17.CrossRefPubMed
go back to reference D’Cruz, A. M., Mosconi, M. W., Ragozzino, M. E., Pavuluri, M., & Sweeney, J. A. (2011). Human reversal learning under conditions of certain versus uncertain outcomes. NeuroImage, 56, 315–322.CrossRefPubMedCentralPubMed D’Cruz, A. M., Mosconi, M. W., Ragozzino, M. E., Pavuluri, M., & Sweeney, J. A. (2011). Human reversal learning under conditions of certain versus uncertain outcomes. NeuroImage, 56, 315–322.CrossRefPubMedCentralPubMed
go back to reference D’Cruz, A., Ragozzino, M. E., Mosconi, M. W., Shrestha, S., Cook, E. H., & Sweeney, J. A. (2013). Reduced behavioral flexibility is related to “Insistence on Sameness” in Autism Spectrum Disorders. Neuropsychology, 27(2), 152–160.CrossRefPubMedCentralPubMed D’Cruz, A., Ragozzino, M. E., Mosconi, M. W., Shrestha, S., Cook, E. H., & Sweeney, J. A. (2013). Reduced behavioral flexibility is related to “Insistence on Sameness” in Autism Spectrum Disorders. Neuropsychology, 27(2), 152–160.CrossRefPubMedCentralPubMed
go back to reference Dias, R., Robbins, T. W., & Roberts, A. C. (1997). Dissociable forms of inhibitory control within prefrontal cortex with an analogue of the Wisconsin Card Sort Test: Restriction to novel situations and independence from ‘on-line’ processing. Journal of Neuroscience, 17, 9285–9297.PubMed Dias, R., Robbins, T. W., & Roberts, A. C. (1997). Dissociable forms of inhibitory control within prefrontal cortex with an analogue of the Wisconsin Card Sort Test: Restriction to novel situations and independence from ‘on-line’ processing. Journal of Neuroscience, 17, 9285–9297.PubMed
go back to reference Elliot, C. D. (2007). Differential Ability Scales-II (DAS-II). San Antonio, TX: Pearson Clinical. Elliot, C. D. (2007). Differential Ability Scales-II (DAS-II). San Antonio, TX: Pearson Clinical.
go back to reference Figueroa, I. J., & Youmans, R. Y. (2013). Failure to maintain set: A measure of distractibility or cognitive flexibility? In: Proceedings of the 57th annual human factors and ergonomics society. Figueroa, I. J., & Youmans, R. Y. (2013). Failure to maintain set: A measure of distractibility or cognitive flexibility? In: Proceedings of the 57th annual human factors and ergonomics society.
go back to reference Floresco, S. B., Ghods-Sharifi, S., Vexelman, C., & Tse, M. T. (2006). Dissociable roles for the nucleus accumbens core and shell in regulating set shifting. Journal of Neuroscience, 26, 2449–2457.CrossRefPubMed Floresco, S. B., Ghods-Sharifi, S., Vexelman, C., & Tse, M. T. (2006). Dissociable roles for the nucleus accumbens core and shell in regulating set shifting. Journal of Neuroscience, 26, 2449–2457.CrossRefPubMed
go back to reference Gastambide, F., Cotel, M. C., Gilmour, G., O’Neill, M. J., Robbins, T. W., & Tricklebank, M. D. (2012). Selective remediation of reversal learning deficits in the neurodevelopmental MAM model of schizophrenia by a novel mGlu5 positive allosteric modulator. Neuropsychopharmacology, 37(4), 1057–1066.CrossRefPubMedCentralPubMed Gastambide, F., Cotel, M. C., Gilmour, G., O’Neill, M. J., Robbins, T. W., & Tricklebank, M. D. (2012). Selective remediation of reversal learning deficits in the neurodevelopmental MAM model of schizophrenia by a novel mGlu5 positive allosteric modulator. Neuropsychopharmacology, 37(4), 1057–1066.CrossRefPubMedCentralPubMed
go back to reference Geurts, H. M., Corbett, B., & Solomon, M. (2009). The paradox of cognitive flexibility in autism. Trends in Cognitive Science, 13(2), 74–82.CrossRef Geurts, H. M., Corbett, B., & Solomon, M. (2009). The paradox of cognitive flexibility in autism. Trends in Cognitive Science, 13(2), 74–82.CrossRef
go back to reference Goldberg, M. C., Mostofsky, S. H., Cutting, L. E., Mahone, E. M., Astor, B. C., Denckla, M. B., et al. (2005). Subtle executive impairment in children with autism and children with ADHD. Journal of Autism and Developmental Disorders, 35(3), 279–293.CrossRefPubMed Goldberg, M. C., Mostofsky, S. H., Cutting, L. E., Mahone, E. M., Astor, B. C., Denckla, M. B., et al. (2005). Subtle executive impairment in children with autism and children with ADHD. Journal of Autism and Developmental Disorders, 35(3), 279–293.CrossRefPubMed
go back to reference Gordon, C. T. (2000). Commentary: Considerations on the pharmacological treatment of compulsions and stereotypies with serotonin reuptake inhibitors in pervasive developmental disorders. Journal of Autism and Developmental Disorders, 30, 437–438.CrossRefPubMed Gordon, C. T. (2000). Commentary: Considerations on the pharmacological treatment of compulsions and stereotypies with serotonin reuptake inhibitors in pervasive developmental disorders. Journal of Autism and Developmental Disorders, 30, 437–438.CrossRefPubMed
go back to reference Grant, D. A., & Berg, E. A. (1948). A behavioral analysis of degree of reinforcement and ease of shifting to new responses in a Weigl-type card sorting problem. Journal of Experimental Psychology, 34, 404–411.CrossRef Grant, D. A., & Berg, E. A. (1948). A behavioral analysis of degree of reinforcement and ease of shifting to new responses in a Weigl-type card sorting problem. Journal of Experimental Psychology, 34, 404–411.CrossRef
go back to reference Heaton, R. K., Chelune, G. J., Talley, J. L., Kay, G. G., & Curtiss, G. (1993). Wisconsin card sorting test manual: Revised and expanded. Odessa, FL: Psychological Assessment Resources. Heaton, R. K., Chelune, G. J., Talley, J. L., Kay, G. G., & Curtiss, G. (1993). Wisconsin card sorting test manual: Revised and expanded. Odessa, FL: Psychological Assessment Resources.
go back to reference Kaland, N., Smith, L., & Mortensen, E. L. (2008). Brief report: Cognitive flexibility and focused attention in children and adolescents with Asperger syndrome and high-functioning autism as measured on the computerized version of the Wisconsin Card Sorting Test. Journal of Autism and Developmental Disorders, 38(6), 1161–1165.CrossRefPubMed Kaland, N., Smith, L., & Mortensen, E. L. (2008). Brief report: Cognitive flexibility and focused attention in children and adolescents with Asperger syndrome and high-functioning autism as measured on the computerized version of the Wisconsin Card Sorting Test. Journal of Autism and Developmental Disorders, 38(6), 1161–1165.CrossRefPubMed
go back to reference Kenet, T., Orekhova, E. V., Bharadwaj, H., Shetty, N. R., Israeli, E., Lee, A. K., et al. (2012). Disconnectivity of the cortical ocular motor control network in autism spectrum disorders. NeuroImage, 61(4), 1226–1234.CrossRefPubMedCentralPubMed Kenet, T., Orekhova, E. V., Bharadwaj, H., Shetty, N. R., Israeli, E., Lee, A. K., et al. (2012). Disconnectivity of the cortical ocular motor control network in autism spectrum disorders. NeuroImage, 61(4), 1226–1234.CrossRefPubMedCentralPubMed
go back to reference Kenworthy, L., Yerys, B. E., Anthony, L. G., & Wallace, G. L. (2008). Understanding executive control in autism spectrum disorders in the lab and in the real world. Neuropsychology Review, 18(4), 320–338.CrossRefPubMedCentralPubMed Kenworthy, L., Yerys, B. E., Anthony, L. G., & Wallace, G. L. (2008). Understanding executive control in autism spectrum disorders in the lab and in the real world. Neuropsychology Review, 18(4), 320–338.CrossRefPubMedCentralPubMed
go back to reference Kim, J., & Ragozzino, M. E. (2005). The involvement of the orbitofrontal cortex in learning under changing task contingencies. Neurobiology of Learning and Memory, 83, 125–133.CrossRefPubMedCentralPubMed Kim, J., & Ragozzino, M. E. (2005). The involvement of the orbitofrontal cortex in learning under changing task contingencies. Neurobiology of Learning and Memory, 83, 125–133.CrossRefPubMedCentralPubMed
go back to reference Kuhlthau, K., Orlich, F., Hall, T. A., Sikora, D., Kovacs, E. A., Delahaye, J., et al. (2010). Health-related quality of life in children with autism spectrum disorders: Results from the Autism Treatment Network. Journal of Autism and Developmental Disorders, 40(6), 721–729.CrossRefPubMed Kuhlthau, K., Orlich, F., Hall, T. A., Sikora, D., Kovacs, E. A., Delahaye, J., et al. (2010). Health-related quality of life in children with autism spectrum disorders: Results from the Autism Treatment Network. Journal of Autism and Developmental Disorders, 40(6), 721–729.CrossRefPubMed
go back to reference Kurtz, M. M., Ragland, J. D., Moberg, P. J., & Gur, R. C. (2004). The Penn Conditional Exclusion Test: A new measure of executive-function with alternate forms. Archives of Clinical Neuropsychology, 19, 191–201.CrossRefPubMed Kurtz, M. M., Ragland, J. D., Moberg, P. J., & Gur, R. C. (2004). The Penn Conditional Exclusion Test: A new measure of executive-function with alternate forms. Archives of Clinical Neuropsychology, 19, 191–201.CrossRefPubMed
go back to reference Landa, R. J., & Goldberg, M. C. (2005). Language, social, and executive functions in high-functioning autism: A continuum of performance. Journal of Autism and Developmental Disorders, 35, 557–573.CrossRefPubMed Landa, R. J., & Goldberg, M. C. (2005). Language, social, and executive functions in high-functioning autism: A continuum of performance. Journal of Autism and Developmental Disorders, 35, 557–573.CrossRefPubMed
go back to reference Langen, M., Leemans, A., Johnston, P., Ecker, C., Daly, E., Murphy, C. M., et al. (2012). Fronto-striatal circuitry and inhibitory control in autism: Findings from diffusion tensor imaging tractography. Cortex, 48(2), 183–193.CrossRefPubMed Langen, M., Leemans, A., Johnston, P., Ecker, C., Daly, E., Murphy, C. M., et al. (2012). Fronto-striatal circuitry and inhibitory control in autism: Findings from diffusion tensor imaging tractography. Cortex, 48(2), 183–193.CrossRefPubMed
go back to reference LeCouteur, A., Rutter, M., Lord, C., & Rios, P. (1989). Autism diagnostic interview: A standardized investigator-based instrument. Journal of Autism and Developmental Disorders, 19(3), 363–387.CrossRef LeCouteur, A., Rutter, M., Lord, C., & Rios, P. (1989). Autism diagnostic interview: A standardized investigator-based instrument. Journal of Autism and Developmental Disorders, 19(3), 363–387.CrossRef
go back to reference Leekam, S. R., Prior, M. R., & Uljarevic, M. (2011). Restricted and repetitive behaviors in autism spectrum disorders: A review of research in the last decade. Psychological Bulletin, 137(4), 562–593.CrossRefPubMed Leekam, S. R., Prior, M. R., & Uljarevic, M. (2011). Restricted and repetitive behaviors in autism spectrum disorders: A review of research in the last decade. Psychological Bulletin, 137(4), 562–593.CrossRefPubMed
go back to reference Liss, M., Fein, D., Allen, D., Dunn, M., Feinstein, C., Morris, R., et al. (2001). Executive functioning in high-functioning children with autism. Journal of Child Psychology and Psychiatry, 42(2), 261–270.CrossRefPubMed Liss, M., Fein, D., Allen, D., Dunn, M., Feinstein, C., Morris, R., et al. (2001). Executive functioning in high-functioning children with autism. Journal of Child Psychology and Psychiatry, 42(2), 261–270.CrossRefPubMed
go back to reference Lopez, B. R., Lincoln, A. J., Ozonoff, S., & Lai, Z. (2005). Examining the relationship between executive functions and restricted, repetitive symptoms of Autistic Disorder. Journal of Autism and Developmental Disorders, 35(4), 445–460.CrossRefPubMed Lopez, B. R., Lincoln, A. J., Ozonoff, S., & Lai, Z. (2005). Examining the relationship between executive functions and restricted, repetitive symptoms of Autistic Disorder. Journal of Autism and Developmental Disorders, 35(4), 445–460.CrossRefPubMed
go back to reference Lord, C., Rutter, M., DiLavore, P. C., Risi, S., Gotham, K., & Bishop, S. (2012). Autism Diagnostic Observation Schedule, Second Edition (ADOS-2). Los Angeles, CA: Western Psychological Services. Lord, C., Rutter, M., DiLavore, P. C., Risi, S., Gotham, K., & Bishop, S. (2012). Autism Diagnostic Observation Schedule, Second Edition (ADOS-2). Los Angeles, CA: Western Psychological Services.
go back to reference Lord, C., Rutter, M., Goode, S., Heemsbergen, J., Jordan, H., Mawhood, L., et al. (1989). Autism Diagnostic Observation Schedule: A standardized observation of communicative and social behavior. Journal of Autism and Developmental Disorders, 19, 185–212.CrossRefPubMed Lord, C., Rutter, M., Goode, S., Heemsbergen, J., Jordan, H., Mawhood, L., et al. (1989). Autism Diagnostic Observation Schedule: A standardized observation of communicative and social behavior. Journal of Autism and Developmental Disorders, 19, 185–212.CrossRefPubMed
go back to reference McAlonan, K., & Brown, V. J. (2003). Orbital prefrontal cortex mediates reversal learning and not attentional set shifting in the rat. Behavior and Brain Research, 146, 97–103.CrossRef McAlonan, K., & Brown, V. J. (2003). Orbital prefrontal cortex mediates reversal learning and not attentional set shifting in the rat. Behavior and Brain Research, 146, 97–103.CrossRef
go back to reference McAlonan, K., Cheung, V., Cheung, C., Suckling, J., Lam, G. Y., Tai, K. S., et al. (2005). Mapping the brain in autism. A voxel-based MRI study of volumetric differences and intercorrelations in autism. Brain, 128(2), 268–276.CrossRefPubMed McAlonan, K., Cheung, V., Cheung, C., Suckling, J., Lam, G. Y., Tai, K. S., et al. (2005). Mapping the brain in autism. A voxel-based MRI study of volumetric differences and intercorrelations in autism. Brain, 128(2), 268–276.CrossRefPubMed
go back to reference Minshew, N. J., Goldstein, G., & Siegel, D. J. (1997). Neuropsychologic functioning in autism: Profile of a complex information processing disorder. Journal of the International Neuropsychological Society, 3(4), 303–316.PubMed Minshew, N. J., Goldstein, G., & Siegel, D. J. (1997). Neuropsychologic functioning in autism: Profile of a complex information processing disorder. Journal of the International Neuropsychological Society, 3(4), 303–316.PubMed
go back to reference Mohler, E. G., Baker, P. M., Gannon, K. S., Jones, S. S., Shacham, S., Sweeney, J. A., et al. (2012). Psychopharmacology (Berl), 220(4), 687–696.CrossRef Mohler, E. G., Baker, P. M., Gannon, K. S., Jones, S. S., Shacham, S., Sweeney, J. A., et al. (2012). Psychopharmacology (Berl), 220(4), 687–696.CrossRef
go back to reference Mooney, E. L., Gray, K. M., Tonge, B. J., Sweeney, D. J., & Taffe, J. R. (2009). Factor analytic study of repetitive behaviours in young children with pervasive developmental disorders. Journal of Autism and Developmental Disorders, 39(5), 765–774.CrossRefPubMed Mooney, E. L., Gray, K. M., Tonge, B. J., Sweeney, D. J., & Taffe, J. R. (2009). Factor analytic study of repetitive behaviours in young children with pervasive developmental disorders. Journal of Autism and Developmental Disorders, 39(5), 765–774.CrossRefPubMed
go back to reference Mosconi, M. W., Kay, M., Seidenfeld, A., Guter, S., Stanford, L. D., & Sweeney, J. A. (2009). Impaired cognitive control is associated with higher-order repetitive behaviors in autism spectrum disorders. Psychological Medicine, 39, 1355–1366.CrossRef Mosconi, M. W., Kay, M., Seidenfeld, A., Guter, S., Stanford, L. D., & Sweeney, J. A. (2009). Impaired cognitive control is associated with higher-order repetitive behaviors in autism spectrum disorders. Psychological Medicine, 39, 1355–1366.CrossRef
go back to reference Munson, J., Dawson, G., Sterling, L., Beauchaine, T., Zhou, A., Koehler, E., et al. (2008). Evidence for latent classes of IQ in young children with autism spectrum disorder. American Journal of Mental Retardation, 113(6), 439–452.CrossRefPubMedCentralPubMed Munson, J., Dawson, G., Sterling, L., Beauchaine, T., Zhou, A., Koehler, E., et al. (2008). Evidence for latent classes of IQ in young children with autism spectrum disorder. American Journal of Mental Retardation, 113(6), 439–452.CrossRefPubMedCentralPubMed
go back to reference Ozonoff, S. (1995). Reliability and validity of the Wisconsin Card Sorting Test in studies of autism. Neuropsychology, 9(4), 491–500.CrossRef Ozonoff, S. (1995). Reliability and validity of the Wisconsin Card Sorting Test in studies of autism. Neuropsychology, 9(4), 491–500.CrossRef
go back to reference Ozonoff, S., Cook, I., Coon, H., Dawson, G., Joseph, R., Klin, A., et al. (2004). Performance on CANTAB subtests sensitive to frontal lobe function in people with autistic disorder: Evidence from the CPEA network. Journal of Autism and Developmental Disorders, 34, 139–150.CrossRefPubMed Ozonoff, S., Cook, I., Coon, H., Dawson, G., Joseph, R., Klin, A., et al. (2004). Performance on CANTAB subtests sensitive to frontal lobe function in people with autistic disorder: Evidence from the CPEA network. Journal of Autism and Developmental Disorders, 34, 139–150.CrossRefPubMed
go back to reference Ozonoff, S., Rogers, S. J., & Pennington, B. F. (1991). Asperger’s syndrome: Evidence of an empirical distinction from high-functioning autism. Journal of Child Psychology and Psychiatry, 32, 1107–1122.CrossRefPubMed Ozonoff, S., Rogers, S. J., & Pennington, B. F. (1991). Asperger’s syndrome: Evidence of an empirical distinction from high-functioning autism. Journal of Child Psychology and Psychiatry, 32, 1107–1122.CrossRefPubMed
go back to reference Palencia, C. A., & Ragozzino, M. E. (2004). The influence of NMDA receptors in the dorsomedial striatum on response reversal learning. Neurobiology of Learning and Memory, 82, 81–89.CrossRefPubMed Palencia, C. A., & Ragozzino, M. E. (2004). The influence of NMDA receptors in the dorsomedial striatum on response reversal learning. Neurobiology of Learning and Memory, 82, 81–89.CrossRefPubMed
go back to reference Pellicano, E. (2007). Links between theory of mind and executive function in young children with autism: Clues to developmental primacy. Developmental Psychology, 43, 974–990.CrossRefPubMed Pellicano, E. (2007). Links between theory of mind and executive function in young children with autism: Clues to developmental primacy. Developmental Psychology, 43, 974–990.CrossRefPubMed
go back to reference Pellicano, E. (2010). The development of core cognitive skills in autism: A 3-year prospective study. Child Development, 81(5), 1400–1416.CrossRefPubMed Pellicano, E. (2010). The development of core cognitive skills in autism: A 3-year prospective study. Child Development, 81(5), 1400–1416.CrossRefPubMed
go back to reference Ragozzino, M. E. (2007). The contribution of the medial prefrontal cortex, orbitofrontal cortex, and dorsomedial striatum to behavioral flexibility. Annals of the New York Academy of Sciences, 1121, 355–375.CrossRefPubMed Ragozzino, M. E. (2007). The contribution of the medial prefrontal cortex, orbitofrontal cortex, and dorsomedial striatum to behavioral flexibility. Annals of the New York Academy of Sciences, 1121, 355–375.CrossRefPubMed
go back to reference Ragozzino, M. E., & Choi, D. (2004). Dynamic changes in acetylcholine output in the medial striatum during place reversal learning. Learning and Memory, 11(1), 70–77.CrossRefPubMedCentralPubMed Ragozzino, M. E., & Choi, D. (2004). Dynamic changes in acetylcholine output in the medial striatum during place reversal learning. Learning and Memory, 11(1), 70–77.CrossRefPubMedCentralPubMed
go back to reference Ragozzino, M. E., Detrich, S., & Kesner, R. P. (1999). Involvement of the prelimbic-infralimbic areas of the rodent prefrontal cortex in behavioral flexibility for place and response learning. Journal of Neuroscience, 19, 4585–4594.PubMed Ragozzino, M. E., Detrich, S., & Kesner, R. P. (1999). Involvement of the prelimbic-infralimbic areas of the rodent prefrontal cortex in behavioral flexibility for place and response learning. Journal of Neuroscience, 19, 4585–4594.PubMed
go back to reference Ragozzino, M. E., Ragozzino, K. E., Mizumori, S. J., & Kesner, R. P. (2002). Role of the dorsomedial striatum in behavioral flexibility for response and visual cue discrimination learning. Behavioral Neuroscience, 116, 105–115.CrossRefPubMedCentralPubMed Ragozzino, M. E., Ragozzino, K. E., Mizumori, S. J., & Kesner, R. P. (2002). Role of the dorsomedial striatum in behavioral flexibility for response and visual cue discrimination learning. Behavioral Neuroscience, 116, 105–115.CrossRefPubMedCentralPubMed
go back to reference Ranier, G. (2007). Behavioral flexibility and the frontal lobe. Neuron, 53(3), 321–323.CrossRef Ranier, G. (2007). Behavioral flexibility and the frontal lobe. Neuron, 53(3), 321–323.CrossRef
go back to reference Ravizza, S. M., Solomon, M., Ivry, R. B., & Carter, C. S. (2013). Restricted and repetitive behaviors in autism spectrum disorders: The relationship of attention and motor deficits. Development and Psychopathology, 25, 773–784.CrossRefPubMed Ravizza, S. M., Solomon, M., Ivry, R. B., & Carter, C. S. (2013). Restricted and repetitive behaviors in autism spectrum disorders: The relationship of attention and motor deficits. Development and Psychopathology, 25, 773–784.CrossRefPubMed
go back to reference Rinehart, N. J., Bradshaw, J. L., Brereton, A. V., & Tonge, B. J. (2002). Lateralization in individuals with high-functioning autism and Asperger’s disorder: A frontostriatal model. Journal of Autism and Developmental Disorders, 32(4), 321–332.CrossRefPubMed Rinehart, N. J., Bradshaw, J. L., Brereton, A. V., & Tonge, B. J. (2002). Lateralization in individuals with high-functioning autism and Asperger’s disorder: A frontostriatal model. Journal of Autism and Developmental Disorders, 32(4), 321–332.CrossRefPubMed
go back to reference Rinehart, N. J., Bradshaw, J. L., Moss, S. A., Brereton, A. V., & Tonge, B. (2001). A deficit in shifting attention present in high-functioning autism but not Asperger’s disorder. Autism, 5(1), 67–80.CrossRefPubMed Rinehart, N. J., Bradshaw, J. L., Moss, S. A., Brereton, A. V., & Tonge, B. (2001). A deficit in shifting attention present in high-functioning autism but not Asperger’s disorder. Autism, 5(1), 67–80.CrossRefPubMed
go back to reference Rutter, M., Bailey, A., & Lord, C. (2003). Social Communication Questionnaire. Los Angeles, CA: Western Psychological Services. Rutter, M., Bailey, A., & Lord, C. (2003). Social Communication Questionnaire. Los Angeles, CA: Western Psychological Services.
go back to reference Sears, L. L., Vest, C., Mohamed, S., Bailey, J., Ranson, B. J., & Piven, J. (1999). An MRI study of the basal ganglia in autism. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 23(4), 613–624.CrossRefPubMed Sears, L. L., Vest, C., Mohamed, S., Bailey, J., Ranson, B. J., & Piven, J. (1999). An MRI study of the basal ganglia in autism. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 23(4), 613–624.CrossRefPubMed
go back to reference Shafritz, K. M., Dichter, G. S., Baranek, G. T., & Belger, A. (2008). The neural circuitry mediating shifts in behavioral response and cognitive set in autism. Biological Psychiatry, 63(10), 974–980.CrossRefPubMedCentralPubMed Shafritz, K. M., Dichter, G. S., Baranek, G. T., & Belger, A. (2008). The neural circuitry mediating shifts in behavioral response and cognitive set in autism. Biological Psychiatry, 63(10), 974–980.CrossRefPubMedCentralPubMed
go back to reference Solomon, M., Smith, A. C., Frank, M. J., Stanford, L., & Carter, C. S. (2011). Probabilistic reinforcement learning in adults with autism spectrum disorders. Autism Research, 4(2), 109–120.CrossRefPubMed Solomon, M., Smith, A. C., Frank, M. J., Stanford, L., & Carter, C. S. (2011). Probabilistic reinforcement learning in adults with autism spectrum disorders. Autism Research, 4(2), 109–120.CrossRefPubMed
go back to reference South, M., Ozonoff, S., & McMahon, W. M. (2007). The relationship between executive functioning, central coherence, and repetitive behaviors in the high-functioning autism spectrum. Autism, 11(5), 437–451.CrossRefPubMed South, M., Ozonoff, S., & McMahon, W. M. (2007). The relationship between executive functioning, central coherence, and repetitive behaviors in the high-functioning autism spectrum. Autism, 11(5), 437–451.CrossRefPubMed
go back to reference Takarae, Y., Minshew, N. J., Luna, B., Krisky, C. M., & Sweeney, J. A. (2004). Pursuit eye movement deficits in autism. Brain, 127, 2584–2594.CrossRefPubMed Takarae, Y., Minshew, N. J., Luna, B., Krisky, C. M., & Sweeney, J. A. (2004). Pursuit eye movement deficits in autism. Brain, 127, 2584–2594.CrossRefPubMed
go back to reference Takarae, Y., Minshew, N. J., Luna, B., & Sweeney, J. A. (2007). Atypical involvement of frontostriatal systems during sensorimotor control in autism. Psychiatry Research, 156(2), 117–127.CrossRefPubMedCentralPubMed Takarae, Y., Minshew, N. J., Luna, B., & Sweeney, J. A. (2007). Atypical involvement of frontostriatal systems during sensorimotor control in autism. Psychiatry Research, 156(2), 117–127.CrossRefPubMedCentralPubMed
go back to reference Turner, M. (1997). Towards an executive dysfunction account of repetitive behaviour in autism. In J. Russell (Ed.), Autism as an executive disorder (pp. 57–100). Oxford, NY: Oxford University Press. Turner, M. (1997). Towards an executive dysfunction account of repetitive behaviour in autism. In J. Russell (Ed.), Autism as an executive disorder (pp. 57–100). Oxford, NY: Oxford University Press.
go back to reference Van Eylen, L. V., Boets, B., Steyaert, J., Evers, K., Wagemans, J., & Noens, I. (2011). Cognitive flexibility in autism spectrum disorder: Explaining the inconsistencies? Research in Autism Spectrum Disorders, 5, 1390–1401.CrossRef Van Eylen, L. V., Boets, B., Steyaert, J., Evers, K., Wagemans, J., & Noens, I. (2011). Cognitive flexibility in autism spectrum disorder: Explaining the inconsistencies? Research in Autism Spectrum Disorders, 5, 1390–1401.CrossRef
go back to reference Veenstra-VanderWeele, J., & Blakely, R. D. (2011). Networking in autism: Leveraging genetic, biomarker, and model system findings in the search for new treatments. Neuropsychopharmacology Reviews, 37, 196–212.CrossRefPubMedCentralPubMed Veenstra-VanderWeele, J., & Blakely, R. D. (2011). Networking in autism: Leveraging genetic, biomarker, and model system findings in the search for new treatments. Neuropsychopharmacology Reviews, 37, 196–212.CrossRefPubMedCentralPubMed
go back to reference Voelbel, G. T., Bates, M. E., Buckman, J. F., Pandina, G., & Hendren, R. L. (2006). Caudate nucleus volume and cognitive performance: Are they related in childhood psychopathology? Biological Psychiatry, 60(9), 942–950.CrossRefPubMedCentralPubMed Voelbel, G. T., Bates, M. E., Buckman, J. F., Pandina, G., & Hendren, R. L. (2006). Caudate nucleus volume and cognitive performance: Are they related in childhood psychopathology? Biological Psychiatry, 60(9), 942–950.CrossRefPubMedCentralPubMed
go back to reference Wechsler, D. (1999). Wechsler abbreviated scale of intelligence. San Antonio, TX: Pearson Clinical. Wechsler, D. (1999). Wechsler abbreviated scale of intelligence. San Antonio, TX: Pearson Clinical.
go back to reference Yerys, B. E., Wallace, G. L., Harrison, B., Celano, M. J., Giedd, J. N., & Kenworthy, L. E. (2009). Set-shifting in children with autism spectrum disorder: Reversal shifting deficits on the Intradimensional/Extradimensional Shift Test correlate with repetitive behaviors. Autism, 13(5), 523–538.PubMedCentralPubMed Yerys, B. E., Wallace, G. L., Harrison, B., Celano, M. J., Giedd, J. N., & Kenworthy, L. E. (2009). Set-shifting in children with autism spectrum disorder: Reversal shifting deficits on the Intradimensional/Extradimensional Shift Test correlate with repetitive behaviors. Autism, 13(5), 523–538.PubMedCentralPubMed
Metagegevens
Titel
Cognitive Set Shifting Deficits and Their Relationship to Repetitive Behaviors in Autism Spectrum Disorder
Auteurs
Haylie L. Miller
Michael E. Ragozzino
Edwin H. Cook
John A. Sweeney
Matthew W. Mosconi
Publicatiedatum
01-03-2015
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 3/2015
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-014-2244-1

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