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Gepubliceerd in: Cognitive Therapy and Research 2/2007

01-04-2007 | Original Paper

Cognitive Deficits in Depression and Functional Specificity of Regional Brain Activity

Auteurs: Rebecca L. Levin, Wendy Heller, Aprajita Mohanty, John D. Herrington, Gregory A. Miller

Gepubliceerd in: Cognitive Therapy and Research | Uitgave 2/2007

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Abstract

The growing literature on cognitive deficits in depression is considered in light of regional brain activity as well as comorbid anxiety and life stressors. Cognitive impairments associated with depression are reviewed, with an emphasis on various aspects of executive function such as memory, attention, and problem-solving. These deficits are related to patterns of brain activity observed in prefrontal, anterior cingulate, and parietal cortices, as well as in subcortical regions. Evidence for the largely unexplored role of environmental stressors in depression and their impact on cognition and brain function is also examined, and promising avenues of additional research are noted. In addition to promoting interdisciplinary research, systematically assessing variables such as cognitive performance, comorbid anxiety, and relevant stressors may elucidate distinct patterns of brain function and cognition that could inform prevention and intervention.
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Metagegevens
Titel
Cognitive Deficits in Depression and Functional Specificity of Regional Brain Activity
Auteurs
Rebecca L. Levin
Wendy Heller
Aprajita Mohanty
John D. Herrington
Gregory A. Miller
Publicatiedatum
01-04-2007
Gepubliceerd in
Cognitive Therapy and Research / Uitgave 2/2007
Print ISSN: 0147-5916
Elektronisch ISSN: 1573-2819
DOI
https://doi.org/10.1007/s10608-007-9128-z

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