Top

Cognitive Therapy and Research

Gepubliceerd in:

21-09-2020 | Original Article

Cognitive Control Training in Healthy Older Adults: A Proof of Concept Study on the Effects on Cognitive Functioning, Emotion Regulation and Affect

Auteurs: Marie-Anne Vanderhasselt, Ineke Demeyer, Leila Van Imschoot, Kristof Hoorelbeke, Rudi De Raedt

Gepubliceerd in: Cognitive Therapy and Research | Uitgave 5/2021

Abstract

Background

The current study sets out to explore the influence of a well-studied cognitive control training (CCT) procedure on cognitive control processes, emotion regulation (ER) and self-reported affect in older adults.

Methods

Thirty-nine healthy older adults (aged 64–78) participated in a randomized controlled proof-of-concept trial. Twenty-one of these participants performed 10 sessions of CCT that loads on working memory and sustained attention, the other eighteen performed 10 sessions of an active placebo training.

Results

CCT beneficially impacted task-specific transfer, but the training did not result in transfer to an unrelated cognitive control task (Stroop task). In addition, no effects were observed on ER processes or affect changes immediately following training, nor at 6 weeks follow-up.

Conclusion

At this point, the CCT seems not suitable to enhance cognitive resilience factors in older non-depressed individuals. However, there is need for more research on possible moderators of the effects, as well as larger-scale studies with longer follow-up measurements.

vorige artikel Online Cognitive Control Training for Remitted Depressed Individuals: A Replication and Extension Study

volgende artikel The Effects of Emotional Working Memory Training on Worry Symptoms and Error-Related Negativity of Individuals with High Trait Anxiety: A Randomized Controlled Study

This study was part of a larger project, also investigating the relationship between ageing, proactive control and attentional bias. Therefore, the AX-CPT (measured before the intervention), the Behavior Rating Inventory of Executive Function (BRIEF, measured before and after the intervention) and the eye tracking task with emotional stimuli (measured after the intervention) were also collected but data will not be presented in the current manuscript. Analyses of the BRIEF revealed no effect of the intervention, completely in line with the reported null-finding in the current paper. Due to various technical reasons, we are unable to annotate each daily training data file to every specific participant during the home-based trainings sessions. Hence, the link between training performance and outcome measures could not be investigated.

Anguera, J. A., Gunning, F. M., & Arean, P. A. (2017). Improving late life depression and cognitive control through the use of therapeutic video game technology: A proof-of-concept randomized trial. Depression and Anxiety, 34(6), 508–517. https://doi.org/10.1002/da.22588.CrossRefPubMedPubMedCentral

Baier, B., Karnath, H. O., Dieterich, M., Birklein, F., Heinze, C., & Muller, N. G. (2010). Keeping memory clear and stable: The contribution of human basal ganglia and prefrontal cortex to working memory. Journal of Neuroscience, 30(29), 9788–9792. https://doi.org/10.1523/JNEUROSCI.1513-10.2010.CrossRefPubMed

Botvinick, M. M., Braver, T. S., Barch, D. M., Carter, C. S., & Cohen, J. D. (2001). Conflict monitoring and cognitive control. Psychological Review, 108(3), 624–652. https://doi.org/10.1037/0033-295X.108.3.624.CrossRefPubMed

Braver, T. S., Paxton, J. L., Locke, H. S., & Barch, D. M. (2009). Flexible neural mechanisms of cognitive control within human prefrontal cortex. Proceedings of the National Academy of Sciences United States of America, 106(18), 7351–7356. https://doi.org/10.1073/pnas.0808187106.CrossRef

Brunoni, A. R., Boggio, P. S., De Raedt, R., Bensenor, I. M., Lotufo, P. A., Namur, V., et al. (2014). Cognitive control therapy and transcranial direct current stimulation for depression: A randomized, double-blinded, controlled trial. Journal of Affective Disorders, 162, 43–49. https://doi.org/10.1016/j.jad.2014.03.026.CrossRefPubMed

Cabeza, R., & Dennis, N. A. (2013). Frontal lobes and aging: Deterioration and compensation. In D. T. Stuss & R. T. Knight (Eds.), Principles of frontal lobe function (2nd ed., pp. 628–652). New York: Oxford University Press.

De Raedt, R., & Koster, E. H. (2010). Understanding vulnerability for depression from a cognitive neuroscience perspective: A reappraisal of attentional factors and a new conceptual framework. Cognitive, Affective, & Behavioral Neuroscience, 10(1), 50–70. https://doi.org/10.3758/CABN.10.1.50.CrossRef

Devilly, G. J., & Borkovec, T. D. (2000). Psychometric properties of the credibility/expectancy questionnaire. Journal of Behavior Therapy and Experimental Psychiatry, 31(2), 73–86. https://doi.org/10.1016/S0005-7916(00)00012-4.CrossRefPubMed

Garnefski, N., Kraaij, V., & Spinhoven, P. (2001). Negative life events, cognitive emotion regulation and emotional problems. Personality and Individual Differences, 30(8), 1311–1327. https://doi.org/10.1016/S0191-8869(00)00113-6.CrossRef

Gross, J. J., & Thompson, R. A. (2007). Emotion regulation: Conceptual foundations. New York: Guilford.

Guye, S., Röcke, C., Mérillat, S., von Bastian, C. C., & Martin, M. (2016). Adult lifespan. In T. Strobach & J. Karbach (Eds.), Cognitive training: An overview of features and applications (pp. 45–57). Cham: Springer.CrossRef

Hammes, J. G. W. (1978). Stroop kleur-woord Test: Dutch manual. Lisse: Swets & Zeitlinger BV.

Hoorelbeke, K., & Koster, E. H. W. (2017). Internet-delivered cognitive control training as a preventive intervention for remitted depressed patients: Evidence from a double-blind randomized controlled trial study. Journal of Consulting and Clinical Psychology, 85(2), 135–146. https://doi.org/10.1037/ccp0000128.CrossRefPubMed

Hoorelbeke, K., Koster, E. H. W., Vanderhasselt, M. A., Callewaert, S., & Demeyer, I. (2015). The influence of cognitive control training on stress reactivity and rumination in response to a lab stressor and naturalistic stress. Behaviour Research and Therapy, 69, 1–10. https://doi.org/10.1016/j.brat.2015.03.010.CrossRefPubMed

Hoorelbeke, K., Koster, E. H. W., Demeyer, I., Loeys, T., & Vanderhasselt, M. A. (2016). Effects of cognitive control training on the dynamics of (Mal) adaptive emotion regulation in daily life. Emotion, 16(7), 945–956. https://doi.org/10.1037/emo0000169.CrossRefPubMed

Joormann, J. (2010). Cognitive inhibition and emotion regulation in depression. Current Directions in Psychological Science, 19(3), 161–166. https://doi.org/10.1177/0963721410370293.CrossRef

Koster, E., Hoorelbeke, K., Onraedt, T., Owens, M., & Derakshan, N. (2017). Cognitive control interventions for depression: A systematic review of findings from training studies. Clinical Psychology Review, 53, 79–92.CrossRef

Liang, Y., Huo, M., Kennison, R., & Zhou, R. (2017). The role of cognitive control in older adult cognitive reappraisal: Detached and positive reappraisal. Frontiers in Behavioral Neuroscience, 11, 27. https://doi.org/10.3389/fnbeh.2017.00027.CrossRefPubMedPubMedCentral

Matysiak, O., Kroemeke, A., & Brzezicka, A. (2019). Working memory capacity as a predictor of cognitive training efficacy in the elderly population. Frontiers in Aging Neuroscience, 11, 126.CrossRef

McGuire, J. T., & Botvinick, M. M. (2010). Prefrontal cortex, cognitive control, and the registration of decision costs. Proceedings of the National Academy of Sciences United states of America, 107(17), 7922–7926. https://doi.org/10.1073/pnas.0910662107.CrossRef

Mella, N., Fagot, D., Renaud, O., Kliegel, M., & De Ribaupierre, A. (2018). Individual differences in developmental change: Quantifying the amplitude and heterogeneity in cognitive change across old age. Journal of Intelligence. https://doi.org/10.3390/jintelligence6010010.CrossRefPubMedPubMedCentral

Motter, J. N., Pimontel, M. A., Rindskop, D., Devanand, D. P., Murali Doraiswamy, P., & Sneed, J. R. (2016). Computerized cognitive training and functional recovery in major depressive disorder: A meta-analysis. Journal of Affective Disorders, 189, 184–191.CrossRef

Nguyen, L., Murphy, K., & Andrews, G. (2019). Immediate and long-term efficacy of executive functions cognitive training in older adults: A systematic review and meta-analysis. Psychological Bulletin, 145(7), 698–733. https://doi.org/10.1037/bul0000196.CrossRefPubMed

Ochsner, K. N., & Gross, J. J. (2005). The cognitive control of emotion. Trends in Cognitive Sciences, 9(5), 242–249. https://doi.org/10.1016/j.tics.2005.03.010.CrossRefPubMed

Orlov, N. D., Tracy, D. K., Joyce, D., Patel, S., Rodzinka-Pasko, J., Dolan, H., et al. (2017). Stimulating cognition in schizophrenia: A controlled pilot study of the effects of prefrontal transcranial direct current stimulation upon memory and learning. Brain Stimulation, 10(3), 560–566. https://doi.org/10.1016/j.brs.2016.12.013.CrossRefPubMed

Peckham, A. D., & Johnson, S. L. (2018). Cognitive control training for emotion-related impulsivity. Behaviour Research and Therapy, 105, 17–26. https://doi.org/10.1016/j.brat.2018.03.009.CrossRefPubMedPubMedCentral

Raz, N., Lindenberger, U., Rodrigue, K. M., Kennedy, K. M., Head, D., Williamson, A., et al. (2005). Regional brain changes in aging healthy adults: General trends, individual differences and modifiers. Cerebral Cortex, 15(11), 1676–1689. https://doi.org/10.1093/cercor/bhi044.CrossRefPubMed

Remue, J., Vanderhasselt, M. A., Baeken, C., Rossi, V., Tullo, J., & De Raedt, R. (2016). The effect of a single HF-rTMS session over the left DLPFC on the physiological stress response as measured by heart rate variability. Neuropsychology, 30(6), 756–766. https://doi.org/10.1037/neu0000255.CrossRefPubMed

Ruf, S. P., Fallgatter, A. J., & Plewnia, C. (2017). Augmentation of working memory training by transcranial direct current stimulation (tDCS). Science Reports, 7(1), 876. https://doi.org/10.1038/s41598-017-01055-1.CrossRef

Sanchez-Lopez, A., Vanderhasselt, M. A., Allaert, J., Baeken, C., & De Raedt, R. (2018). Neurocognitive mechanisms behind emotional attention: Inverse effects of anodal tDCS over the left and right DLPFC on gaze disengagement from emotional faces. Cognitive, Affective, & Behavioral Neuroscience, 18(3), 485–494. https://doi.org/10.3758/s13415-018-0582-8.CrossRef

Siegle, G. J., Ghinassi, F., & Thase, M. E. (2007). Neurobehavioral therapies in the 21st century: Summary of an emerging field and an extended example of cognitive control training for depression. Cognitive Therapy and Research, 31(2), 235–262. https://doi.org/10.1007/s10608-006-9118-6.CrossRef

Siegle, G. J., Price, R. B., Jones, N. P., Ghinassi, F., Painter, T., & Thase, M. E. (2014). You gotta work at it. Clinical Psychological Science, 2(4), 455–471. https://doi.org/10.1177/2167702614536160.CrossRef

Treynor, W., Gonzalez, R., & Nolen-Hoeksema, S. (2003). Rumination reconsidered: A psychometric analysis. Cognitive Therapy and Research, 27, 247–259. https://doi.org/10.1023/A:1023910315561.CrossRef

Vanderhasselt, M. A., Baeken, C., Van Schuerbeek, P., Luypaert, R., De Mey, J., & De Raedt, R. (2013a). How brooding minds inhibit negative material: An event-related fMRI study. Brain and Cognition, 81(3), 352–359. https://doi.org/10.1016/j.bandc.2013.01.007.CrossRefPubMed

Vanderhasselt, M. A., Brunoni, A. R., Loeys, T., Boggio, P. S., & De Raedt, R. (2013b). Nosce te ipsum: Socrates revisited? Controlling momentary ruminative self-referent thoughts by neuromodulation of emotional working memory. Neuropsychologia, 51(13), 2581–2589. https://doi.org/10.1016/j.neuropsychologia.2013.08.011.CrossRefPubMed

Vanderhasselt, M. A., Koster, E. H. W., Onraedt, T., Bruyneel, L., Goubert, L., & De Raedt, R. (2014). Adaptive cognitive emotion regulation moderates the relationship between dysfunctional attitudes and depressive symptoms during a stressful life period: A prospective study. Journal of Behavior Therapy and Experimental Psychiatry, 45(2), 291–296. https://doi.org/10.1016/j.jbtep.2014.01.003.CrossRefPubMed

Vanderhasselt, M. A., De Raedt, R., Namur, V., Lotufo, P. A., Bensenor, I. M., Boggio, P. S., et al. (2015). Transcranial electric stimulation and neurocognitive training in clinically depressed patients: A pilot study of the effects on rumination. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 57, 93–99. https://doi.org/10.1016/j.pnpbp.2014.09.015.CrossRefPubMed

Vervaeke, J., Hoorelbeke, K., Baeken, C., Van Looy, J., & Koster, E. H. W. (2019). Transfer and motivation after cognitive control training for remitted depression in healthy sample. Journal of Cognitive Enhancement, 4(1), 49–61. https://doi.org/10.1007/s41465-019-00135-6.CrossRef

Watson, D., Clark, L. A., & Tellegen, A. (1988). Development and validation of brief measures of positive and negative affect: The PANAS scales. Journal of Personality and Social Psychology, 54(6), 1063–1070. https://doi.org/10.1037//0022-3514.54.6.1063.CrossRefPubMed

Zetsche, U., Burkner, P. C., & Schulze, L. (2018). Shedding light on the association between repetitive negative thinking and deficits in cognitive control: A meta-analysis. Clinical Psychology Review, 63, 56–65. https://doi.org/10.1016/j.cpr.2018.06.001.CrossRefPubMed

Titel: Cognitive Control Training in Healthy Older Adults: A Proof of Concept Study on the Effects on Cognitive Functioning, Emotion Regulation and Affect
Auteurs: Marie-Anne Vanderhasselt
Ineke Demeyer
Leila Van Imschoot
Kristof Hoorelbeke
Rudi De Raedt
Publicatiedatum: 21-09-2020
Uitgeverij: Springer US
Gepubliceerd in: Cognitive Therapy and Research / Uitgave 5/2021
Print ISSN: 0147-5916
Elektronisch ISSN: 1573-2819
DOI: https://doi.org/10.1007/s10608-020-10154-9

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Background

Methods

Results

Conclusion

Log in om toegang te krijgen

Andere artikelen Uitgave 5/2021

Correction to: A Prospective Investigation of the Impact of Distinct Posttraumatic (PTSD) Symptom Clusters on Suicidal Ideation

Brain of Thrones: Cognitive Effort and Perceived Performance During a Cognitive Task in Major Depressive Disorder

Rumination: Practicing Retrieval of Autobiographical Memories

Imagery Rescripting of Painful Memories in Social Anxiety Disorder: A Qualitative Analysis of Needs Fulfillment and Memory Updating

The Effects of Emotional Working Memory Training on Worry Symptoms and Error-Related Negativity of Individuals with High Trait Anxiety: A Randomized Controlled Study

Emotional Memory: Concluding Remarks to the Special Issue on Memory Training for Emotional Disorders