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01-04-2008 | Original Paper

Cognitive and Behavioral Mediators of Combined Pharmacotherapy and Psychotherapy of Chronic Depression

Auteurs: Janice A. Blalock, Rachel T. Fouladi, Paul M. Cinciripini, John C. Markowitz, Daniel N. Klein, Barbara O. Rothbaum, Bruce A. Arnow, Rachel Manber, Lawrence P. Riso, Dawen Sui, James P. McCullough Jr

Gepubliceerd in: Cognitive Therapy and Research | Uitgave 2/2008

Abstract

This study examined coping styles and attributions for negative events among chronically depressed outpatients to determine whether these variables mediated differences in depression treatment outcome between combined nefazodone and cognitive behavioral analysis system of psychotherapy (CBASP), versus nefazodone and CBASP alone. Chronically depressed outpatients (N = 517) who completed the initial 12-week treatment phase were included in the analyses. Attributional style and coping met criteria for partial mediation of the combination treatment effect over nefazodone, accounting for 60% of the difference in treatment outcome. Escape-avoidant coping met criteria for partial mediation of the combination treatment effect over CBASP, accounting for 37% of the treatment differential. Among all of the cognitive and coping variables evaluated, escape-avoidance coping emerged as the dominant mediating variable. These findings suggest that nefazodone and CBASP each produced changes in maladaptive cognitions and coping, and that the superiority of combined treatment was partially accounted for by the additive effects of both forms of treatment on these variables.

vorige artikel Moderating effects of sociotropy and autonomy on affective and self-esteem reactivity to daily stressors

volgende artikel Implicit and Explicit Self-Esteem and Attractiveness Beliefs among Individuals with Body Dysmorphic Disorder

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Titel: Cognitive and Behavioral Mediators of Combined Pharmacotherapy and Psychotherapy of Chronic Depression
Auteurs: Janice A. Blalock
Rachel T. Fouladi
Paul M. Cinciripini
John C. Markowitz
Daniel N. Klein
Barbara O. Rothbaum
Bruce A. Arnow
Rachel Manber
Lawrence P. Riso
Dawen Sui
James P. McCullough Jr
Publicatiedatum: 01-04-2008
Uitgeverij: Springer US
Gepubliceerd in: Cognitive Therapy and Research / Uitgave 2/2008
Print ISSN: 0147-5916
Elektronisch ISSN: 1573-2819
DOI: https://doi.org/10.1007/s10608-006-9092-z

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