Top

Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-12-2013 | Original Paper

Co-segregation of Social Cognition, Executive Function and Local Processing Style in Children with ASD, their Siblings and Normal Controls

Auteurs: Anoek M. Oerlemans, Katharina Droste, Daphne J. van Steijn, Leo M. J. de Sonneville, Jan K. Buitelaar, Nanda N. J. Rommelse

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 12/2013

Abstract

Cognitive research proposes that social cognition (SC), executive functions (EF) and local processing style (weak CC) may be fruitful areas for research into the familial-genetic underpinnings of Autism Spectrum Disorders (ASD). The performance of 140 children with ASD, 172 siblings and 127 controls on tasks measuring SC (face recognition, affective prosody, and facial emotion recognition), EF (inhibition, cognitive flexibility, and verbal working memory) and local processing style was assessed. Compelling evidence was found for the interrelatedness of SC and EF, but not local processing style, within individuals and within families, suggesting that these domains tend to co-segregate in ASD. Using the underlying shared variance of these constructs in genetic research may increase the power for detecting susceptibility genes for ASD.

vorige artikel Teacher and Child Predictors of Achieving IEP Goals of Children with Autism

volgende artikel Atypical Gaze Following in Autism: A Comparison of Three Potential Mechanisms

American Psychiatric Association. (2000). Diagnostic and statistical manual of disorders, fourth edition, text revision. Washington DC: American Psychiatric Association.CrossRef

Baron-Cohen, S., Leslie, A., & Frith, U. (1985). Does the autistic child have a ‘theory of mind’? Cognition, 21, 37–46.PubMedCrossRef

Bernier, R., Gerdts, J., Munson, J., Dawson, G., & Estes, A. (2011). Evidence for broader autism phenotype characteristics in parents from multiple-incidence families. Autism Research, 5(1), 13–20.PubMedCrossRef

Berument, S. K., Rutter, M., Lord, C., Pickles, A., & Bailey, A. (1999). Autism screening questionnaire: Diagnostic validity. British Journal of Psychiatry, 175, 444–451.PubMedCrossRef

Bishop, D. V. M., Maybery, M., Wong, D., Maley, A., & Hallmayer, J. (2006). Characteristics of the broader phenotype in autism: A study of siblings using the children’s communication checklist-2. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics), 141B, 117–122.CrossRef

Buitelaar, J. K., & Van der Wees, M. (1997). Are deficits in the decoding of affective cues and in metalizing abilities independent? Journal of Autism and Developmental Disorders, 27(5), 539–556.PubMedCrossRef

Carlson, S. M., & Moses, L. J. (2001). Individual differences in inhibitory control and children’s theory of mind. Child Development, 72, 1032–1053.PubMedCrossRef

Carlson, S. M., Moses, L. J., & Breton, C. (2002). How specific is the relation between executive function and theory of mind?, Contributions of inhibitory control and working memory. Infant and Child Development, 11, 73–92.CrossRef

Carlson, S. M., Mandell, D. J., & Williams, L. (2004). Executive function and theory of mind: stability and prediction from ages 2–3. Developmental Psychology, 40, 1105–1122.PubMedCrossRef

Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Hillsdale: Erlbaum.

Corsello, C., Hus, V., Pickles, A., Risi, S., Cook, E. H, Jr, Leventhal, B. L., et al. (2007). Between a ROC and a hard place: decision making and making decisions about using the SCQ. Journal of Child Psychology and Psychiatry, 48, 932–940.PubMedCrossRef

De Sonneville, L. M. J. (1999). Amsterdam Neuropsychological Tasks: A computer aided assessment program. In B. P. L. M. Den Brinker, P. J. Beek, A. N. Brand, F. J. Maarse, & L. J. M. Mulder (Eds.), Cognitive ergonomics, clinical assessment and computer assisted learning: Computers in psychology (pp. 187–203). Lisse: Swets and Zeitlinger.

De Sonneville, L.M.J. (2005). Amsterdam Neuropsychological Tasks: scientific and clinical applications. Tijdschrift voor Neuropsychologie, 1, 27–41 (Dutch).

De Sonneville, L.M.J. (2011). Amsterdam Neuropsychological Tasks, Manual, Amsterdam, The Netherlands: SONARES; http://www.sonares.nl/index.php?language=2.

Frazier-Wood, A. C., Bralten, J., Arias-Vasquez, A., Luman, M., Oosterlaan, J., Sergeant, J., et al. (2012). Neuropsychological intra-individual variability explains unique genetic variance of ADHD and shows suggestive linkage to chromosomes 12, 13 and 17. Journal of Medical Genetics Part B Neuropsychiatric Genetics, 159B, 131–140.CrossRef

Freitag, C. M. (2007). The genetics of autistic disorders and its clinical relevance: A review of the literature. Molecular Psychiatry, 12(1), 2–22.PubMedCrossRef

Frith, U. (1989). Autism: Explaining the Enigma. Oxford: Blackwell.

Frith, U., & Happé, F. (1994). Autism: Beyond ‘theory of mind’. Cognition, 50, 115–132.PubMedCrossRef

Geurts, H. M., Verté, S., Oosterlaan, J., Roeyers, H., & Sergeant, J. A. (2004). How specific are executive function deficits in attention deficit hyperactivity disorder and autism? Journal of Child Psychology and Psychiatry, 45, 836–854.PubMedCrossRef

Golan, O., Baron-Cohen, S., Hill, J. J., & Rutherford, M. D. (2007). The ‘Reading the mind in the voice’ test-revised: A study of complex emotion recognition in adults with and without autism spectrum conditions. Journal of Autism and Developmental Disorders, 37, 1096–1106.PubMedCrossRef

Gottesman, I. I., & Gould, T. D. (2003). The endophenotype concept in psychiatry: Etymology and strategic intentions. American Journal of Psychiatry, 160, 636–645.PubMedCrossRef

Goussé, V., Stilgenbauer, J.-L., Delorme, R., Mouren, M. C., Michel, G., & Leboyer, M. (2009). Ėtude des profils cognitifs chez les apparentės de personnes avec autisme: hypothese du`n manque de flexibilitė cognitive? Annales Mėdico-Psycholiques, 167, 704–708.CrossRef

Groth-Marnat, G. (1997). Handbook of psychological assessment (3rd ed.). New York: Wiley.

Happé, F. (2003). Cognition in autism: One deficit or many? Novartis Foundation Symposium, 17, 198–207.CrossRef

Happé, F., & Frith, U. (2006). The weak central coherence account: Detail-focused cognitive style in autism spectrum disorders. Journal of Autism and Developmental Disorders, 36(1), 5–25.PubMedCrossRef

Happé, F., & Ronald, A. (2008). The ‘Fractionable Autism Triad’: A review of evidence from behavioral, genetic, cognitive and neural research. Neuropsychology Review, 18, 287–304.PubMedCrossRef

Happé, F., Briskman, J., & Frith, U. (2001). Exploring the cognitive phenotype of autism: weak “central coherence” in parents and siblings of children with autism: I. Experimental tests. Journal of Child Psychology and Psychiatry, 42(3), 299–307.PubMedCrossRef

Happé, F., Ronald, A., & Plomin, R. (2006). Time to give up a single explanation for autism. Nature Neuroscience, 9(10), 1218–1220.PubMedCrossRef

Harms, M. B., Martin, A., & Wallace, G. L. (2010). Facial emotion recognition in autism spectrum disorders: A review of behavioral and neuroimaging studies. Neuropsychology Review, 20, 290–322.PubMedCrossRef

Hill, E. L. (2004a). Executive function in autism. TRENDS in Cognitive Sciences, 8(1), 26–32.PubMedCrossRef

Hill, E. L. (2004b). Evaluating the theory of executive dysfunction in autism. Developmental Review, 24, 189–233.CrossRef

Holt, R., & Monaco, A. P. (2011). Links between genetics and pathophysiology in the autism spectrum disorders. EMBO Molecular Medicine, 3(8), 438–450.PubMedCrossRef

Jarrold, C., Butler, D. W., Cottington, E. M., & Jiminez, F. (2000). Linking theory of mind and CC bias in autism and in the general population. Journal of Autism and Developmental Disorders, 27, 25–37.CrossRef

Korpilahti, P., Jansson-Verkasalo, E., Mattila, M. L., Kuusikko, S., Suominen, K., Rytky, S., et al. (2007). Processing of affective speech prosody is impaired in Asperger’s syndrome. Journal of Autism and Developmental Disorders, 37, 1539–1549.PubMedCrossRef

Le Couteur, A., Lord, C., & Rutter, M. (2003). The autism diagnostic interview—revised (ADI-R). Los Angeles: CA: Western psychological services.

Lindner, J. L., & Rosén, L. A. (2006). Decoding of emotion through facial expression, prosody and verbal content in children and adolescents with Asperger’s Syndrome. Journal of Autism and Developmental Disorders, 36, 769–777.PubMedCrossRef

Losh, M., Childress, D., Lam, K., & Piven, J. (2008). Defining key features of the broad autism phenotype: a comparison across multiple- and- single-incidence families of autistic individuals. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics), 147B, 424–433.CrossRef

Losh, M., Adolphs, R., Poe, M. D., Couture, S., Penn, D., Baranek, G. T., et al. (2009). Neuropsychological profile of autism and the broad autism phenotype. Archives of General Psychiatry, 66(5), 518–526.PubMedCrossRef

Morgan, B., Maybery, M., & Durkin, K. (2003). Weak central coherence, poor joint attention, and low verbal ability: Independent deficits in early autism. Developmental Psychology, 39, 646–656.PubMedCrossRef

Norusis, M. J. (1992). Statistical package for the social sciences, SPSS/PC+. New York: McGraw-Hill.

Nydén, A., Hagberg, B., Goussé, V., & Rastam, M. (2011). A cognitive endophenotype of autism in families with multiple incidence. Research in Autism Spectrum Disorders, 5(1), 191–200.CrossRef

Ozonoff, S. (1997). Components of executive function in autism and other disorders. In J. Russell (Ed.), Autism as an executive disorder (pp. 179–211). Oxford: Oxford University Press.

Ozonoff, S., Pennington, B. F., & Rogers, S. J. (1991). Executive function deficits in high-functioning autistic individuals: Relationship to theory of mind. Journal of Child Psychology and Psychiatry, 37, 51–87.

Pellicano, E. (2007). Links between theory of mind and executive function in young children with autism: Clues to developmental primacy. Developmental Psychology, 43(4), 974–990.PubMedCrossRef

Pellicano, E. (2010). Individual differences in executive function and central coherence predict developmental changes in theory of mind in autism. Developmental Psychology, 46(2), 530–544.PubMedCrossRef

Pellicano, E., Maybery, M., & Durkin, K. (2005). Central coherence in typically developing preschoolers: Does it cohere and does it relate to ToM and executive control? Journal of Child Psychology and Psychiatry, 46, 533–547.PubMedCrossRef

Pellicano, E., Maybery, M., Durkin, K., & Maley, A. (2006). Multiple cognitive capabilities deficits in children with an autism spectrum disorder: “Weak” central coherence and its relationship to theory of mind and executive control. Development and Psychopathology, 18, 77–98. USA: Cambridge University Press.PubMedCrossRef

Philip, R. C. M., Whalley, H. C., Stanfield, A. C., Sprengelmeyer, R., Santos, I. M., Young, A. W., et al. (2010). Deficits in facial, body movement and vocal emotional processing in autism spectrum disorders. Psychological Medicine, 40, 1919–1929.PubMedCrossRef

Pisula, E. (2010). The autistic mind in the light of neuropsychological studies. Acta Neurobiologiae Experimentalis, 70(2), 119–130.PubMed

Piven, J., Palmer, P., Landa, R., Santangelo, S., Jacobi, D., & Childress, D. (1997). Personality and language characteristics in parents from multiple-incidence autism families. American Journal of Medical Genetics (Neuropsychiatric Genetics), 74, 398–411.CrossRef

Preacher, K. J. (2002). Calculation for the test of the difference between two independent correlation coefficients [Computer software]. Available from http://quantpsy.org.

Rommelse, N. N. J., Altink, M. E., Oosterlaan, J., Buschgens, C. J. M., Buitelaar, J., & Sergeant, J. A. (2008). Support for an independent familial segregation of executive and intelligence endophenotypes in ADHD-families. Psychological Medicine, 38(11), 1595–1606.PubMedCrossRef

Rommelse, N. N. J., Geurts, H. M., Franke, B., Buitelaar, J. K., & Hartman, C. A. (2011). A review on cognitive and brain endophenotypes that may be common in autism spectrum disorder and attention-deficit/hyperactivity disorder and facilitate the search for pleiotropic genes. Neuroscience and Biobehavioral Reviews, 35(6), 1363–1396.PubMedCrossRef

Ronald, A., Happé, F., Bolton, P., Butcher, L. M., Price, T. S., Wheelwright, S., et al. (2006). Genetic heterogeneity between the three components of the autism spectrum: A twin study. Journal of Child and Adolescent Psychiatry, 45(6), 691–699.CrossRef

Serra, M., Althaus, M., De Sonneville, L. M. J., Stant, A. D., Jackson, A. E., & Minderaa, R. B. (2003). Face recognition in children with a pervasive developmental disorder not otherwise specified. Journal of Autism and Developmental Disorders, 33, 303–317.PubMedCrossRef

Sham, P. C., Cherny, S. S., Purcell, S., & Hewitt, J. K. (2000). Power of linkage versus association analysis of quantative traits, by use of variance-components models, for sibship data. American Journal of Human Genetics, 66, 1616–1630.PubMedCrossRef

Tabachnick, B. G., & Fidell, L. S. (2001). Using multivariate statistics (4th ed.). Needham Heights: Allyn and Bacon.

Turner, M. (1997). Towards an executive dysfunction account of repetitive behaviour in autism. In J. Russell (Ed.), Autism as an executive disorder (pp. 57–100). New York: USA: Oxford University Press.

Van der Meer, J. M. J., Oerlemans, A. M., Van Steijn, D. J., Lappenschaar, M. G. A., De Sonneville, L. M. J., Buitelaar, J. K., et al. (2012). Are ASD and ADHD different manifestations of one overarching disorder? Cognitive and symptom evidence from a clinical and population based sample. Journal of the American Academy of Child and Adolescent Psychiatry, 51(11), 1160–1172.PubMedCrossRef

Van Steijn, D. J., Richards, J. S., Oerlemans, A. M., De Ruiter, S. W., Van Aken, M. A. G., Franke, B., et al. (2012). The co-occurrence of attention-deficit/hyperactivity disorder and autism spectrum disorder symptoms in parents of children with ASD or ASD with ADHD. Journal of Child Psychology and Psychiatry, 53(9), 954–963.PubMedCrossRef

Vingerhoets, G., Berckmoes, C., & Stroobant, N. (2003). Cerebral hemodynamics during discrimination of prosodic and semantic emotion in speech studied by transcranial doppler ultrasonography. Neuropsychology, 17, 93–99.PubMedCrossRef

Wallace, S., Sebastian, C., Pellicano, E., Parr, J., & Bailey, A. (2010). Face processing abilities in relatives of individuals with ASD. Autism Research, 3(6), 345–349.PubMedCrossRef

Wechsler, D. (2000). WAIS-III Nederlandstalige bewerking. Technische handleiding. London: The Psychological Corporation.

Wechsler, D. (2002). WISC-III Handleiding. London: The Psychological Corporation.

Wilson, C. E., Freeman, P., Brock, J., Burton, A. M., & Palermo, R. (2010). Facial identity recognition in het broader autism phenotype. PLoS ONE, 5(9), e12876.PubMedCrossRef

Wong, D., Mayberry, M., Bishop, D. V. M., Maley, A., & Hallmayer, J. (2006). Profiles of executive function in parents and siblings of individuals with autism spectrum disorders. Genes, Brain and Behavior, 5, 561–576.CrossRef

Titel: Co-segregation of Social Cognition, Executive Function and Local Processing Style in Children with ASD, their Siblings and Normal Controls
Auteurs: Anoek M. Oerlemans
Katharina Droste
Daphne J. van Steijn
Leo M. J. de Sonneville
Jan K. Buitelaar
Nanda N. J. Rommelse
Publicatiedatum: 01-12-2013
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 12/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-013-1807-x

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen

Andere artikelen Uitgave 12/2013

What are the Mechanisms Behind Exceptional Word Reading Ability in Hyperlexia?: Evidence from a 4-Year-Old Hyperlexic Boy’s Invented Spellings

Asperger’s Disorder will be Back

Brief Report: An Evaluation of the AQ-10 as a Brief Screening Instrument for ASD in Adults

Correlates and Risk Markers for Sleep Disturbance in Participants of the Autism Treatment Network

Teacher and Child Predictors of Achieving IEP Goals of Children with Autism

Cognitive Enhancement Therapy for Adults with Autism Spectrum Disorder: Results of an 18-month Feasibility Study