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Gepubliceerd in: Journal of Behavioral Medicine 2/2019

19-07-2018

Co-occurring reasons for medication nonadherence within subgroups of patients with hyperlipidemia

Auteurs: Dan V. Blalock, Hayden B. Bosworth, Bryce B. Reeve, Corrine I. Voils

Gepubliceerd in: Journal of Behavioral Medicine | Uitgave 2/2019

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Abstract

Medication nonadherence is a significant clinical problem among individuals taking statins. Poor adherence is often attributable to several reasons, yet most adherence interventions target a single reason. Baseline data were examined from a randomized clinical trial of 236 patients with hyperlipidemia. A latent class analysis was then performed on patients reporting any nonadherence (n = 109). A 4-class solution provided the most optimal fit and differentiation of classes. Class 1 (N = 59, 54%) included patients who reported occasionally forgetting. Class 2 (N = 16, 14%) represented patients who were concerned about side effects. Class 3 (N = 17, 16%) represented patients who reported out-of-routine life events as contributing to nonadherence. Class 4 (N = 17, 16%) represented patients who endorsed a large number reasons indiscriminately. Class membership was almost uniformly unrelated to any patient demographic factors or treatment arm. Each cluster of reasons defining these patients may be best addressed through different intervention strategies.
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Metagegevens
Titel
Co-occurring reasons for medication nonadherence within subgroups of patients with hyperlipidemia
Auteurs
Dan V. Blalock
Hayden B. Bosworth
Bryce B. Reeve
Corrine I. Voils
Publicatiedatum
19-07-2018
Uitgeverij
Springer US
Gepubliceerd in
Journal of Behavioral Medicine / Uitgave 2/2019
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521
DOI
https://doi.org/10.1007/s10865-018-9954-3