Skip to main content
Top
Gepubliceerd in: Journal of Child and Family Studies 11/2017

21-06-2017 | Original Paper

Children of Prenatally Depressed Mothers: Externalizing and Internalizing Symptoms are Accompanied by Reductions in Specific Social-Emotional Competencies

Auteurs: Anna Eichler, Lisa Walz, Juliane Grunitz, Jennifer Grimm, Jessica Van Doren, Eva Raabe, Tamme W. Goecke, Peter A. Fasching, Matthias W. Beckmann, Johannes Kornhuber, Oliver Kratz, Hartmut Heinrich, Gunther H. Moll

Gepubliceerd in: Journal of Child and Family Studies | Uitgave 11/2017

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Studies have shown that child development is negatively affected by prenatal depression. A dysregulated hypothalamic-pituitary-adrenal axis in the pregnant woman, passed to the fetus, is one discussed key mechanism. Studies, investigating primary-school age children, have found effects on antisocial behavior. Effects on internalizing symptoms were not found, but the analysis did not distinguish between anxiety and depression symptoms. Additionally, until now, no objective test data operationalizing social-emotional competencies have been included. The present study examined: 1.Whether the effects on child externalizing symptoms could be replicated; 2. If there are specific effects on child internalizing symptoms, separated for anxiety and depression; and 3. Are child clinical symptoms reflected in reductions in social-emotional competencies. A sample of 61 prenatally depressed and 143 prenatally not-depressed women and their 6–9 year old children were compared, controlling for key confounders in both the perinatal period and in middle childhood. Children of prenatally depressed mothers had more antisocial behavior and depression symptoms reported by their mothers. The prediction of antisocial behavior scores tended to be more significant for boys than for girls. Child anxiety symptoms were primarily explained by current maternal depressive symptoms. Children of prenatally depressed mothers also showed a reduction in social-emotional competencies, specifically regarding the ability to interpret complex social situations. This study showed that, even in a non-clinical sample, there are distinct effects of prenatal depression on child externalizing and internalizing symptoms which are accompanied by reductions in specific social-emotional competencies. These results emphasize that treatment for depressed pregnant women and/or early support for affected families is worthwhile. Additional work is required to identify the underlying biological mechanisms.
Literatuur
go back to reference Achenbach, T. M. (1991). Manual for the child behavior checklist/4–18. Burlington, VT: University of Vermont. Achenbach, T. M. (1991). Manual for the child behavior checklist/4–18. Burlington, VT: University of Vermont.
go back to reference Apgar, V. (1966). The newborn (Apgar) scoring system: Reflections and advice. Pediatric Clinics of North America, 13(3), 645–650.CrossRefPubMed Apgar, V. (1966). The newborn (Apgar) scoring system: Reflections and advice. Pediatric Clinics of North America, 13(3), 645–650.CrossRefPubMed
go back to reference Baibazarova, E., van de Beek, C., Cohen-Kettenis, P. T., Buitelaar, J., Shelton, K. H., & van Goozen, S. H. (2013). Influence of prenatal maternal stress, maternal plasma cortisol and cortisol in the amniotic fluid on birth outcomes and child temperament at 3 months. Psychoneuroendocrinology, 38(6), 907–915. doi:10.1016/j.psyneuen.2012.09.015.CrossRefPubMed Baibazarova, E., van de Beek, C., Cohen-Kettenis, P. T., Buitelaar, J., Shelton, K. H., & van Goozen, S. H. (2013). Influence of prenatal maternal stress, maternal plasma cortisol and cortisol in the amniotic fluid on birth outcomes and child temperament at 3 months. Psychoneuroendocrinology, 38(6), 907–915. doi:10.​1016/​j.​psyneuen.​2012.​09.​015.CrossRefPubMed
go back to reference Bortz, J., & Schuster, C. (2010). Statistik für human- und Sozialwissenschaftler. Berlin: Springer.CrossRef Bortz, J., & Schuster, C. (2010). Statistik für human- und Sozialwissenschaftler. Berlin: Springer.CrossRef
go back to reference Cohen, J. (1988). Statistical power analysis for the behavioral sciences. Hillsdale, NJ: Erlbaum. Cohen, J. (1988). Statistical power analysis for the behavioral sciences. Hillsdale, NJ: Erlbaum.
go back to reference Cox, J. L., Chapman, G., Murray, D., & Jones, P. (1996). Validation of the Edinburgh postnatal depression scale (EPDS) in non-postnatal women. Journal of Affective Disorders, 39(3), 185–189.CrossRefPubMed Cox, J. L., Chapman, G., Murray, D., & Jones, P. (1996). Validation of the Edinburgh postnatal depression scale (EPDS) in non-postnatal women. Journal of Affective Disorders, 39(3), 185–189.CrossRefPubMed
go back to reference Cox, J. L., Holden, J. M., & Sagovsky, R. (1987). Detection of postnatal depression: Development of the 10-item Edinburgh postnatal depression scale. The British Journal of Psychiatry, 150, 782–786.CrossRefPubMed Cox, J. L., Holden, J. M., & Sagovsky, R. (1987). Detection of postnatal depression: Development of the 10-item Edinburgh postnatal depression scale. The British Journal of Psychiatry, 150, 782–786.CrossRefPubMed
go back to reference Döpfner, M., Görtz-Dorten, A., Lehmkuhl, G., Breuer, D., & Goletz, H. (2008). Diagnostik-System für psychische Störungen nach ICD-10 und DSM-IV für Kinder und Jugendliche. Bern: Huber. Döpfner, M., Görtz-Dorten, A., Lehmkuhl, G., Breuer, D., & Goletz, H. (2008). Diagnostik-System für psychische Störungen nach ICD-10 und DSM-IV für Kinder und Jugendliche. Bern: Huber.
go back to reference Eichler, A., Grunitz, J., Grimm, J., Walz, L., Raabe, E., Goecke, T. W., et al. (2016). Did you drink alcohol during pregnancy? Inaccuracy and discontinuity of women’s self-reports: On the way to establish meconium ethyl glucuronide (EtG) as a biomarker for alcohol consumption during pregnancy. Alcohol, 54, 39–44. doi:10.1016/j.alcohol.2016.07.002.CrossRefPubMed Eichler, A., Grunitz, J., Grimm, J., Walz, L., Raabe, E., Goecke, T. W., et al. (2016). Did you drink alcohol during pregnancy? Inaccuracy and discontinuity of women’s self-reports: On the way to establish meconium ethyl glucuronide (EtG) as a biomarker for alcohol consumption during pregnancy. Alcohol, 54, 39–44. doi:10.​1016/​j.​alcohol.​2016.​07.​002.CrossRefPubMed
go back to reference Goecke, T. W., Burger, P., Fasching, P. A., Bakdash, A., Engel, A., Haberle, L., et al. (2014). Meconium indicators of maternal alcohol abuse during pregnancy and association with patient characteristics. BioMed Research International, 2014, 702848 doi:10.1155/2014/702848.CrossRefPubMedPubMedCentral Goecke, T. W., Burger, P., Fasching, P. A., Bakdash, A., Engel, A., Haberle, L., et al. (2014). Meconium indicators of maternal alcohol abuse during pregnancy and association with patient characteristics. BioMed Research International, 2014, 702848 doi:10.​1155/​2014/​702848.CrossRefPubMedPubMedCentral
go back to reference Grob, A., Meyer, C., & Hagmann-von Arx, P. (2009). Intelligence and development scales (IDS). Bern: Huber. Grob, A., Meyer, C., & Hagmann-von Arx, P. (2009). Intelligence and development scales (IDS). Bern: Huber.
go back to reference Halberstadt, A. G., Denham, S. A., & Dunsmore, J. (2001). Affective social competence. Social Development, 10, 79–119.CrossRef Halberstadt, A. G., Denham, S. A., & Dunsmore, J. (2001). Affective social competence. Social Development, 10, 79–119.CrossRef
go back to reference Hatzinger, M., Brand, S., Perren, S., von Wyl, A., von Klitzing, K., & Holsboer-Trachsler, E. (2007). Hypothalamic-pituitary-adrenocortical (HPA) activity in kindergarten children: Importance of gender and associations with behavioral/emotional difficulties. Journal of Psychiatric Research, 41(10), 861–870. doi:10.1016/j.jpsychires.2006.07.012.CrossRefPubMed Hatzinger, M., Brand, S., Perren, S., von Wyl, A., von Klitzing, K., & Holsboer-Trachsler, E. (2007). Hypothalamic-pituitary-adrenocortical (HPA) activity in kindergarten children: Importance of gender and associations with behavioral/emotional difficulties. Journal of Psychiatric Research, 41(10), 861–870. doi:10.​1016/​j.​jpsychires.​2006.​07.​012.CrossRefPubMed
go back to reference Hein, A., Rauh, C., Engel, A., Haberle, L., Dammer, U., Voigt, F., et al. (2014). Socioeconomic status and depression during and after pregnancy in the Franconian Maternal Health Evaluation Studies (FRAMES). Archives of Gynecology and Obstetrics, 289(4), 755–763. doi:10.1007/s00404-013-3046-y.CrossRefPubMed Hein, A., Rauh, C., Engel, A., Haberle, L., Dammer, U., Voigt, F., et al. (2014). Socioeconomic status and depression during and after pregnancy in the Franconian Maternal Health Evaluation Studies (FRAMES). Archives of Gynecology and Obstetrics, 289(4), 755–763. doi:10.​1007/​s00404-013-3046-y.CrossRefPubMed
go back to reference Kessler, R. C., Gruber, M., Hettema, J. M., Hwang, I., Sampson, N., & Yonkers, K. A. (2008). Co-morbid major depression and generalized anxiety disorders in the national comorbidity survey follow-up. Psychological Medicine, 38(3), 365–374. doi:10.1017/s0033291707002012.CrossRefPubMed Kessler, R. C., Gruber, M., Hettema, J. M., Hwang, I., Sampson, N., & Yonkers, K. A. (2008). Co-morbid major depression and generalized anxiety disorders in the national comorbidity survey follow-up. Psychological Medicine, 38(3), 365–374. doi:10.​1017/​s003329170700201​2.CrossRefPubMed
go back to reference Korhonen, M., Luoma, I., Salmelin, R., & Tamminen, T. (2014). Maternal depressive symptoms: Associations with adolescents’ internalizing and externalizing problems and social competence. Nordic Journal of Psychiatry, 68(5), 323–332. doi:10.3109/08039488.2013.838804.CrossRefPubMed Korhonen, M., Luoma, I., Salmelin, R., & Tamminen, T. (2014). Maternal depressive symptoms: Associations with adolescents’ internalizing and externalizing problems and social competence. Nordic Journal of Psychiatry, 68(5), 323–332. doi:10.​3109/​08039488.​2013.​838804.CrossRefPubMed
go back to reference Kroes, G., Veerman, J. W., & De Bruyn, E. E. (2003). Bias in parental reports? Maternal psychopathology and the reporting of problem behavior in clinic-referred children. European Journal of Psychological Assessment, 19, 195.CrossRef Kroes, G., Veerman, J. W., & De Bruyn, E. E. (2003). Bias in parental reports? Maternal psychopathology and the reporting of problem behavior in clinic-referred children. European Journal of Psychological Assessment, 19, 195.CrossRef
go back to reference Luoma, I., Kaukonen, P., Mantymaa, M., Puura, K., Tamminen, T., & Salmelin, R. (2004). A longitudinal study of maternal depressive symptoms, negative expectations and perceptions of child problems. Child Psychiatry and Human Development, 35(1), 37–53.CrossRefPubMed Luoma, I., Kaukonen, P., Mantymaa, M., Puura, K., Tamminen, T., & Salmelin, R. (2004). A longitudinal study of maternal depressive symptoms, negative expectations and perceptions of child problems. Child Psychiatry and Human Development, 35(1), 37–53.CrossRefPubMed
go back to reference Luoma, I., Tamminen, T., Kaukonen, P., Laippala, P., Puura, K., Salmelin, R., & Almqvist, F. (2001). Longitudinal study of maternal depressive symptoms and child well-being. Journal of the American Academy of Child & Adolescent Psychiatry, 40(12), 1367–1374. doi:10.1097/00004583-200112000-00006.CrossRef Luoma, I., Tamminen, T., Kaukonen, P., Laippala, P., Puura, K., Salmelin, R., & Almqvist, F. (2001). Longitudinal study of maternal depressive symptoms and child well-being. Journal of the American Academy of Child & Adolescent Psychiatry, 40(12), 1367–1374. doi:10.​1097/​00004583-200112000-00006.CrossRef
go back to reference Mehta, D., Quast, C., Fasching, P. A., Seifert, A., Voigt, F., Beckmann, M. W., et al. (2012). The 5-HTTLPR polymorphism modulates the influence on environmental stressors on peripartum depression symptoms. Journal of Affective Disorders, 136(3), 1192–1197. doi:10.1016/j.jad.2011.11.042.CrossRefPubMed Mehta, D., Quast, C., Fasching, P. A., Seifert, A., Voigt, F., Beckmann, M. W., et al. (2012). The 5-HTTLPR polymorphism modulates the influence on environmental stressors on peripartum depression symptoms. Journal of Affective Disorders, 136(3), 1192–1197. doi:10.​1016/​j.​jad.​2011.​11.​042.CrossRefPubMed
go back to reference Moffitt, T. E., Harrington, H., Caspi, A., Kim-Cohen, J., Goldberg, D., Gregory, A. M., & Poulton, R. (2007). Depression and generalized anxiety disorder: Cumulative and sequential comorbidity in a birth cohort followed prospectively to age 32 years. Archives of General Psychiatry, 64(6), 651–660. doi:10.1001/archpsyc.64.6.651.CrossRefPubMed Moffitt, T. E., Harrington, H., Caspi, A., Kim-Cohen, J., Goldberg, D., Gregory, A. M., & Poulton, R. (2007). Depression and generalized anxiety disorder: Cumulative and sequential comorbidity in a birth cohort followed prospectively to age 32 years. Archives of General Psychiatry, 64(6), 651–660. doi:10.​1001/​archpsyc.​64.​6.​651.CrossRefPubMed
go back to reference O’Connor, T. G., Monk, C., & Fitelson, E. M. (2014). Practitioner review: Maternal mood in pregnancy and child development- implications for child psychology and psychiatry. Journal of Child Psychology and Psychiatry, 55(2), 99–111. doi:10.1111/jcpp.12153.CrossRefPubMed O’Connor, T. G., Monk, C., & Fitelson, E. M. (2014). Practitioner review: Maternal mood in pregnancy and child development- implications for child psychology and psychiatry. Journal of Child Psychology and Psychiatry, 55(2), 99–111. doi:10.​1111/​jcpp.​12153.CrossRefPubMed
go back to reference Pawlby, S., Hay, D. F., Sharp, D., Waters, C. S., & O’Keane, V. (2009). Antenatal depression predicts depression in adolescent offspring: Prospective longitudinal community-based study. Journal of Affective Disorders, 113(3), 236–243. doi:10.1016/j.jad.2008.05.018.CrossRefPubMed Pawlby, S., Hay, D. F., Sharp, D., Waters, C. S., & O’Keane, V. (2009). Antenatal depression predicts depression in adolescent offspring: Prospective longitudinal community-based study. Journal of Affective Disorders, 113(3), 236–243. doi:10.​1016/​j.​jad.​2008.​05.​018.CrossRefPubMed
go back to reference Ravens-Sieberer, U., Wille, N., Erhart, M., Bettge, S., Wittchen, H. U., Rothenberger, A., et al. (2008). Prevalence of mental health problems among children and adolescents in Germany: Results of the BELLA study within the National Health Interview and Examination survey. European Child & Adolescent Psychiatry, 17(Suppl 1), 22–33. doi:10.1007/s00787-008-1003-2.CrossRef Ravens-Sieberer, U., Wille, N., Erhart, M., Bettge, S., Wittchen, H. U., Rothenberger, A., et al. (2008). Prevalence of mental health problems among children and adolescents in Germany: Results of the BELLA study within the National Health Interview and Examination survey. European Child & Adolescent Psychiatry, 17(Suppl 1), 22–33. doi:10.​1007/​s00787-008-1003-2.CrossRef
go back to reference Reulbach, U., Bleich, S., Knorr, J., Burger, P., Fasching, P. A., Kornhuber, J., et al. (2009). Pre-, peri- and postpartal depression. Fortschritte der Neurologie-Psychiatrie, 77(12), 708–713. doi:10.1055/s-0028-1109822.CrossRefPubMed Reulbach, U., Bleich, S., Knorr, J., Burger, P., Fasching, P. A., Kornhuber, J., et al. (2009). Pre-, peri- and postpartal depression. Fortschritte der Neurologie-Psychiatrie, 77(12), 708–713. doi:10.​1055/​s-0028-1109822.CrossRefPubMed
go back to reference Rice, F., Harold, G. T., Boivin, J., Hay, D. F., van den Bree, M., & Thapar, A. (2009). Disentangling prenatal and inherited influences in humans with an experimental design. Proceedings of the National Academy of Sciences of the United States of America, 106(7), 2464–2467. doi:10.1073/pnas.0808798106.CrossRefPubMedPubMedCentral Rice, F., Harold, G. T., Boivin, J., Hay, D. F., van den Bree, M., & Thapar, A. (2009). Disentangling prenatal and inherited influences in humans with an experimental design. Proceedings of the National Academy of Sciences of the United States of America, 106(7), 2464–2467. doi:10.​1073/​pnas.​0808798106.CrossRefPubMedPubMedCentral
go back to reference Rice, F., Harold, G. T., Boivin, J., van den Bree, M., Hay, D. F., & Thapar, A. (2010). The links between prenatal stress and offspring development and psychopathology: Disentangling environmental and inherited influences. Psychological Medicine, 40(2), 335–345. doi:10.1017/s0033291709005911.CrossRefPubMed Rice, F., Harold, G. T., Boivin, J., van den Bree, M., Hay, D. F., & Thapar, A. (2010). The links between prenatal stress and offspring development and psychopathology: Disentangling environmental and inherited influences. Psychological Medicine, 40(2), 335–345. doi:10.​1017/​s003329170900591​1.CrossRefPubMed
go back to reference Ruttle, P. L., Shirtcliff, E. A., Serbin, L. A., Fisher, D. B., Stack, D. M., & Schwartzman, A. E. (2011). Disentangling psychobiological mechanisms underlying internalizing and externalizing behaviors in youth: Longitudinal and concurrent associations with cortisol. Hormones and Behavior, 59(1), 123–132. doi:10.1016/j.yhbeh.2010.10.015.CrossRefPubMed Ruttle, P. L., Shirtcliff, E. A., Serbin, L. A., Fisher, D. B., Stack, D. M., & Schwartzman, A. E. (2011). Disentangling psychobiological mechanisms underlying internalizing and externalizing behaviors in youth: Longitudinal and concurrent associations with cortisol. Hormones and Behavior, 59(1), 123–132. doi:10.​1016/​j.​yhbeh.​2010.​10.​015.CrossRefPubMed
go back to reference Schneider, M., Engel, A., Fasching, P. A., Haberle, L., Binder, E. B., Voigt, F., et al. (2014). Genetic variants in the genes of the stress hormone signalling pathway and depressive symptoms during and after pregnancy. BioMed Research International, 2014, 469278 doi:10.1155/2014/469278.PubMedPubMedCentral Schneider, M., Engel, A., Fasching, P. A., Haberle, L., Binder, E. B., Voigt, F., et al. (2014). Genetic variants in the genes of the stress hormone signalling pathway and depressive symptoms during and after pregnancy. BioMed Research International, 2014, 469278 doi:10.​1155/​2014/​469278.PubMedPubMedCentral
Metagegevens
Titel
Children of Prenatally Depressed Mothers: Externalizing and Internalizing Symptoms are Accompanied by Reductions in Specific Social-Emotional Competencies
Auteurs
Anna Eichler
Lisa Walz
Juliane Grunitz
Jennifer Grimm
Jessica Van Doren
Eva Raabe
Tamme W. Goecke
Peter A. Fasching
Matthias W. Beckmann
Johannes Kornhuber
Oliver Kratz
Hartmut Heinrich
Gunther H. Moll
Publicatiedatum
21-06-2017
Uitgeverij
Springer US
Gepubliceerd in
Journal of Child and Family Studies / Uitgave 11/2017
Print ISSN: 1062-1024
Elektronisch ISSN: 1573-2843
DOI
https://doi.org/10.1007/s10826-017-0819-0

Andere artikelen Uitgave 11/2017

Journal of Child and Family Studies 11/2017 Naar de uitgave