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Gepubliceerd in: Journal of Autism and Developmental Disorders 9/2019

23-05-2019 | Original Paper

Characteristics Associated with Autism Spectrum Disorder Risk in Individuals with Down Syndrome

Auteurs: Marie Moore Channell, Laura J. Hahn, Tracie C. Rosser, Debra Hamilton, Michelle A. Frank-Crawford, George T. Capone, Stephanie L. Sherman, The Down Syndrome Cognition Project

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 9/2019

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Abstract

We examined autism spectrum disorder (ASD) risk in a large national sample of 203 individuals with Down syndrome, 6–25 years old, to determine the association of ASD risk with age, sex, IQ, adaptive behaviors, and maladaptive behaviors. We used a two-pronged approach by (1) considering ASD symptomatology continuously across the sample of individuals with DS and examining associations with each characteristic, and (2) dichotomizing our sample into high and low ASD risk groups and comparing groups on each characteristic. The pattern of results was largely similar across both types of analyses. ASD symptomatology/risk was negatively associated with IQ and adaptive behaviors and positively associated with certain types of maladaptive behaviors. Clinical implications for screening and therapeutic purposes are discussed.
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Metagegevens
Titel
Characteristics Associated with Autism Spectrum Disorder Risk in Individuals with Down Syndrome
Auteurs
Marie Moore Channell
Laura J. Hahn
Tracie C. Rosser
Debra Hamilton
Michelle A. Frank-Crawford
George T. Capone
Stephanie L. Sherman
The Down Syndrome Cognition Project
Publicatiedatum
23-05-2019
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 9/2019
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-019-04074-1