Abstract
It is not the purpose of this chapter to instruct the reader on the topic of attention deficit hyperactivity disorder (ADHD) in general behavioral terms, to review evidence for the neurobiological nature thereof, or to analyze ADHD in terms of models of cognitive neuropsychology; these matters may be reviewed by the reader in this volume, as well as some recent publications (1–3). Resolutely atheoretical, this chapter aims to set forth many questions (but few answers) on the limited (yet multifaceted) issues, important both for research studies and clinical evaluations, connecting the domain of executive function (EF) and/or certain deficits thereof, executive dysfunction (EDF), with the diagnosis of any subtype of ADHD.
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References
Tannock R. Attention deficit hyperactivity disorder: Advances in cognitive, neurobiological, and genetic research. J Child Psychol Psychiatry 1998;39:65–99.
Barkley RA. Issues in the diagnosis of attention deficit/hyperactivity disorder in children. Brain Dev 2003;25:77–83.
Denckla M. ADHD: topic update. Brain Dev 2003;25:383–389.
Barkley RA. ADHD and the Nature of Self Control. New York: Guilford Press, 1997.
Barkley RA. ADHD part I: The executive functions and ADHD. J Am Acad Child Adolesc Psychiatry 2000;39:1064–1068.
Sergeant JA, Geurts H, Oosterlaan J. How specific is a deficit of executive functioning for attention deficit/hyperactivity disorder. Behav Brain Res 2002;130:3–28.
Denckla MB, Reiss AL. Prefrontal-subcortical circuits in developmental disorders. In: Krasnegor NA, Lyon GR, Goldman-Rakic PS, eds. Development of the prefrontal cortex: evolution, neuro-biology, and behavior. Baltimore, MD: Paul H. Brooks, 1997:283–293.
Castellanos FX, Lee PP, Sharp W. Developmental trajectories of brain volume abnormalities in children and adolescents with attention deficit/hyperactivity disorder. JAMA 2002;288:1740–1748.
Durston S. A review of the biological bases of ADHD: What have we learned from imaging studies. Ment Retard Dev Disabil Res Rev 2003;9:84–195.
Denckla M. Minimal brain dysfunction. In: Chall J, Mirsky A, ReLage K, eds. National Society for the Study of Education: education and the brain. Chicago: University of Chicago Press, 1978:223–268.
Denckla M, Rudel R. Anomalies of motor development in hyperactive boys without learning disabilities. Ann Neurol 1978;3:231–233.
Rasmussen P, Gillberg C. Natural outcome of ADHD with developmental coordination disorder at age twenty-two years: a controlled longitudinal community-based study. J Am Acad Child Adolesc Psychiatry 2000;39:1424–1431.
Rourke BP, Strang JD. Neuropsychological significance of variations in patterns of academic performance: motor, psychomotor, and tactile-perceptual abilities. J Pediatr Psychol 1978;3:62–66.
Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV?). Washington, DC: American Psychiatric Association, 1994.
Henderson K. Update 2001: overview of ADA, IDEA, and Section 504. ERIC EC Digest 2001;E606:12–13.
Touwen B, Prechtl H. The neurological examination of the child with minor nervous dysfunction. Philadelphia: JB Lippincott, 1977.
Wolff PH, Gunnoe CE, Cohen C. Neuromotor maturation and psychological performance: a developmental study. Dev Med Child Neurol 1985;27:344–354.
Camp JA, Bialer I, Sverd J, et al. Clinical usefulness of the NIMH physical and neurological examination for soft signs. Am J Psychiatry 1978;135:362–364.
Denckla MB. Revised PANESS. Psychopharm Bull 1985;21:773–800.
Denckla MB. Development of motor coordination in normal children. Dev Med Child Neurol 1974;16:729–741.
Denckla MB. Motor coordination in dyslexic children: theoretical and clinical implications. In: Frank SH, Duffy H, Geschwind N, eds. Dyslexia: a neuroscientific approach to clinical evaluation. Boston: Little, Brown, 1985:187–95.
Nichols P, Chen T. Minimal brain dysfunction: a prospective study. Hillsdale, NJ: Erlbaum Associates, 1981:219–241.
Conners CK. Conners’ Continuous Performance Test Computer Program, Version 3.0. Toronto, Canada: Multi-health Systems, 1994.
Reader MJ, Harris EL, Schuerholz LJ, et al. Attention deficit hyperactivity disorder and executive dysfunction. Dev Neuropsychol 1994;10:493–512.
Denckla MB. Research on executive function in a neurodevelopmental context: application of clinical measures. Dev Neuropsychol 1996;12:5–15.
Fridlund AJ, Delis DC. California Verbal Learning Test-Children’s Version®. The Psychological Corporation. San Antonio, TX: Harcourt Brace & Company, 1998.
Delis-Kaplan Executive Function System™. San Antonio, TX: The Psychological Corporation, 2001.
Spreen O, Straus E. A compendium of neuropsychological tests. New York: Oxford University Press, 1991.
Benton AL, Hamsher K, Varney NR, et al. Contributions to neuropsychological assessment: a clinical manual. New York: Oxford University Press, 1983.
Pennington BF, Ozonoff S. Executive functions and developmental psychopathologies. J Child Psychol Psychiatr Ann Res Rev 1996;37:51–87.
Bernstein JH, Waber DP. Developmental scoring system for the Rey-Osterreith complex figure: professional manual. Odessa, FL: Psychological Assessment Corporation, 1996.
Korkman M, Kirk U, Kemp S. Developmental neuropsychological assessment NEPSY™. San Antonio, TX: Psychological Corporation, 1998;64:156–157.
Rudel RG, Denckla MB, Broman M. Rapid silent responses to repeated target symbols by dyslexic and nondyslexic children. Brain Lang 1978;6:52–58.
Tannock R, Martinussen R, Frijters J. Naming speed performance and stimulant effect indicate effortful semantic processing deficits in attention deficit/hyperactivity disorder. J Abnorm Child Psychol 2000;28:237–252.
Denckla MB, Rudel RG. Rapid automatized naming (RAN) dyslexia differentiated from other learning disabilities. Neuropsychologia 1976;14:471–479.
Gioia GA, Isquith PK, Guy SC, et al. Behavior rating inventory of executive function. Lutz FL: Psychological Assessment Resources, 2000.
Denckla MB. The Behavior Rating Inventory of Executive Function: commentary. Child Neuropsychol 2002;8:304–306.
Pennington BF, Groisser D, Welsh MC. Contrasting cognitive deficits in attention deficit hyperactivity disorder versus reading disability. Dev Psychol 1993;299:511–523.
Bayliss DM, Roodenrys S. Executive processing and attention deficit hyperactivity disorder: An application of the supervisory attentional system. Dev Neuropsychol 2000;17:161–180.
Connors K. Conners’ Rating Scales. North Tonawanda, NY: Multi-Health Systems, Inc., 1997.
Gershon J. A meta-analytic review of gender differences in ADHD. J Atten Disord 2002;5:143–154.
Gaub M, Carlson CL. Gender differences in ADHD: A meta-analysis and critical review. J Am Acad Child Adolesc Psychiatry 1997;36:1036–1045.
Grodzinsky GM, Diamond R. Frontal lobe functioning in boys with attention deficit hyperactivity disorder. Dev Neuropsychol 1992;8:427–445.
Rourke BP. The syndrome of nonverbal learning disabilities: Developmental manifestations in neurological disease, disorder, and dysfunction. Clin Neuropsychol 1988;2:293–330.
Cox CS, Chee E, Chase GA, et al. Reading proficiency affects the construct validity of the Stroop test interference score. Clin Neuropsychol 1997;11:105–110.
Seidman LJ, Biederman J, Faraone SV, et al. Toward defining a neuropsychology of attention deficit hyperactivity disorder: performance of children and adolescents from a large clinical sample. J Consult Clin Psychol 1997;65:150–160.
Luciana M, Nelson CA. Assessment of neuropsychological function through use of the Cambridge Neuropsychological Testing Automated Battery: performance in 4-to 12-year-old children. Dev Neuropsychol 2002;22:595–624.
Goldberg MC, Mostofsky SH, Cutting LE, et al. Subtle executive impairment in children with autism and children with ADHD. Submitted.
Klorman R, Hazel-Fernandez LA, Shaywitz SE. Executive functioning deficits in attention-deficit/hyperactivity disorder are independent of oppositional defiant or reading disorder. J Am Acad Child Adolesc Psychiatry 1999;38:1148–1155.
Taylor HG. Learning disabilities. In: Mash EJ, ed. Behavioral assessments of childhood disorders (2nd ed.). New York: Guilford Press, 1988:402–405.
Romans SM, Roeltgen DP, Kushner H. Executive function in females with Turner syndrome. Dev Neuropsychol 1997;13:23–40.
Bornstein RA. Neuropsychological performance in children with Tourette syndrome. Psychiatry Res 1990;33:73–81.
Yeates KO, Bornstein RA. Attention deficit disorder and neuropsychological functioning in children with Tourette syndrome. Neuropsychology 1994;8:65–74.
Schuerholz LJ, Baumgardner TL, Singer HS, et al. Neuropsychological status of children with Tourette syndrome with and without attention deficit hyperactivity disorder Neurology 1996;46:958–965.
Ozonoff S, Jensen J. Brief report specific executive function profiles in three neurodevelopmental disorders. J Autism Dev Disord 1999;29:171–177.
Singer HS, Reiss AL, Brown JE, et al. Volumetric MRI changes in basal ganglia of children with Tourette syndrome. Neurology 1993;43:950–956.
Baumgardner TL, Singer HS, Denckla MB, et al. Corpus callosum morphology in children with Tourette syndrome and attention deficit hyperactivity disorder. Neurology 1996;4:477–482.
Fredericksen KA, Cutting LE, Kates WR, et al. Disproportionate increases of white matter in right frontal lobe in Tourette syndrome. Neurology 2002;58:85–89.
Eldridge R, Denckla MB, Bien E, et al. Neurofibromatosis type 1 (Recklinghausen’s disease). Am J Dis Child 1989;143:833–837.
Cutting LE, Koth CW, Denckla MB. How children with neurofibromatosis type 1 differ from “typical” learning disabled clinic attenders: nonverbal learning disabilities revisited. Dev Neuropsychol 2000;17:29–47.
North K, Joy P, Yuille D, et al. Cognitive function and academic performance in children with neurofibromatosis type 1. Dev Med Child Neurol. 1995;37:427–436.
Hofman KJ, Harris EL, Bryan RN, et al. Neurofibromatosis type 1: the cognitive phenotype. J Pediatr 1994;124:S1–S8.
Itoh T, Magnaldi S, White RM, et al. Neurofibromatosis type 1: the evolution of deep gray and what matter MR abnormalities. Am J Rad 1994;15:1513–1519.
Moore BD, Slopis JM, Schomer D, et al. Neuropsychological significance of areas of high signal intensity on brain MRIs of children with neurofibromatosis. Neurology 1996;46:1660–1668.
Cutting, LE, Koth, CW, Burdette, C, et al. The relationship of cognitive functioning, whole brain volumes, and T-2 weighted hyperintensities in neurofibromatosis type 1. J Child Neurol 2000;15:157–160.
Cutting LE, Cooper KL, Koth CW, Mostofsky SH, et al. Megalencephaly in NF-1: Predominantly white matter contribution and mitigation by ADHD. Neurology 2002;59:1388–1394.
Rubia K, Overmeyer S, Taylor E, et al. Hypofrontality in attention deficit hyperactivity disorder during higher-order motor control: a study with functional MRI. AM J Psychiatry 1999;156:891–896.
Durston S, Thomas KM, Yang Y, et al. The development of neural systems involved in overriding behavioral responses: an event-related fMRI study. Dev Sci 2002;5:F9–F16.
Vaidya CJ, Austin G, Kirkorian G. Selective effects of methylphenidate in attention deficit hyperactivity disorder: a functional magnetic resonance study. Proc Nat Acad Sci 1998;95:14,494–14,499.
Luna B, Thulborn KR, Munoz DP, et al. Maturation of widely distributed brain functions subserves cognitive development. Neuroimage 2001;13:786–793.
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Denckla, M.B. (2005). Executive Function. In: Gozal, D., Molfese, D.L. (eds) Attention Deficit Hyperactivity Disorder. Contemporary Clinical Neuroscience. Humana Press. https://doi.org/10.1385/1-59259-891-9:165
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DOI: https://doi.org/10.1385/1-59259-891-9:165
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