Abstract
During maximum vasodilation, which corresponds with minimal myocardial resistance, distal coronary pressure divided by aortic pressure equals maximum myocardial blood flow divided by the normally expected value as it would be if no epicardial lesion were present1,2. The theoretical background of the concept of fractional flow reserve and its experimental validation have been provided in the preceding chapters. So far, however, pressure-derived fractional flow reserve was validated in an open chest dog model against the ratio of epicardial hyperemic flow velocity in the presence of a stenosis to hyperemic flow velocity in the absence of a stenosis.
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© 2000 Springer Science+Business Media Dordrecht
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Pijls, N.H.J., De Bruyne, B. (2000). Validation of Fractional Flow Reserve in Humans. In: Coronary Pressure. Developments in Cardiovascular Medicine, vol 195. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-9564-3_8
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DOI: https://doi.org/10.1007/978-94-015-9564-3_8
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