Abstract
Arrhythmogenic right ventricular dysplasia (ARVD) or arrhythmogenic right ventricular cardiomyopathy was first described by Fontaine in 1977 as a disease characterized by the occurrence of ventricular tachycardia (VT) with left bundle branch block morphology and progressive atrophy of the right ventricular myocardium with adipose or fibro-adipose substitution [1]. The cause and pathogenesis of this disease are still unknown. The high degree of familial prevalence strongly suggests a genetic substrate, and so an autosomal dominant transmission with incomplete penetration and variable expression has been supposed [2, 3] and, more recently, the genetic disorder has been located as being in chromosome 14 [4].
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Rizzon, P., Pitzalis, M.V., Luzzi, G., Massari, F., Mastropasqua, F. (1996). Arrhythmogenic right ventricular dysplasia. In: Oto, M.A. (eds) Practice and Progress in Cardiac Pacing and Electrophysiology. Developments in Cardiovascular Medicine, vol 183. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0219-0_6
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DOI: https://doi.org/10.1007/978-94-009-0219-0_6
Publisher Name: Springer, Dordrecht
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