Skip to main content

Neuropsychiatric Assessment of Traumatic Brain Injury During Acute Neurorehabilitation*

  • Chapter
Neuropsychiatric Disorders
  • 1482 Accesses

Abstract

Traumatic brain injury (TBI) is a common and costly problem worldwide. In the United States, 1.5 million people sustain TBI each year, and approximately 230,000 of these require hospitalization for management of their injury. The majority of TBI resulting in hospitalization are moderate to severe in nature and produce significant mortality and morbidity. Among those surviving their injuries, most will develop cognitive, emotional, and behavioral (collectively referred to here as neuropsychiatric) disturbances in the acute postinjury period and will require acute rehabilitation management. These posttraumatic neuropsychiatric sequelae present substantial clinical management challenges that the consulting neuropsychiatrist is well suited to evaluate and manage. In the service of offering the consulting neuro­psychiatrist with information that may be of use in the care of persons with TBI receiving care in the acute neurorehabilitation setting, this chapter first defines and describes TBI and reviews the neuroanatomical and neurobehavioral consequences of TBI relevant to understanding posttraumatic neuropsychiatric disturbances. These disturbances are organized under the framework of posttraumatic encephalopathy, and the characteristic forms and stages of recovery of this condition are discussed. Finally, a neuropsychiatric approach to the evaluation of persons with TBI in the acute inpatient neurorehabilitation setting is described.

This work was supported in part by HealthONE Spalding Rehabilitation Hospital.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Thurman D, Guerrero J (1999) Trends in hospitalization associated with traumatic brain injury. JAMA 282:954–957

    Article  PubMed  CAS  Google Scholar 

  2. Thurman DJ, Alverson C, Dunn KA et al (1999) Traumatic brain injury in the United States: a public health perspective. J Head Trauma Rehabil 14:602–615

    Article  PubMed  CAS  Google Scholar 

  3. Selassie AW, Zaloshnja E, Langlois JA et al (2008) Incidence of long-term disability following traumatic brain injury hospitalization, United States, 2003. J Head Trauma Rehabil 23:123–131

    Article  PubMed  Google Scholar 

  4. Levin HS (1995) Neurobehavioral outcome of closed head injury: implications for clinical trials. J Neurotrauma 12:601–610

    Article  PubMed  CAS  Google Scholar 

  5. severe head injury. Experience of the Traumatic Coma Data Bank. J Neurosurg 73:699–709

    PubMed  Google Scholar 

  6. Rapoport M, McCauley S, Levin H et al (2002) The role of injury severity in neurobehavioral outcome 3 months after traumatic brain injury. Neuropsychiatry Neuropsychol Behav Neurol 15:123–132

    PubMed  Google Scholar 

  7. Hart T, Whyte J, Polansky M et al (2003) Concordance of patient and family report of neurobehavioral symptoms at 1 year after traumatic brain injury. Arch Phys Med Rehabil 84:204–213

    Article  PubMed  Google Scholar 

  8. Kaufman HH, Levin HS, High WM Jr et al (1985) Neurobehavioral outcome after gunshot wounds to the head in adult civilians and children. Neurosurgery (Baltim) 16:754–758

    Article  CAS  Google Scholar 

  9. Dikmen S, Machamer J, Miller B et al (2001) Functional status examination: a new instrument for assessing outcome in traumatic brain injury. J Neurotrauma 18:127–140

    Article  PubMed  CAS  Google Scholar 

  10. Dikmen SS, Machamer JE, Powell JM et al (2003) Outcome 3 to 5 years after moderate to severe traumatic brain injury. Arch Phys Med Rehabil 84:1449–1457

    Article  PubMed  Google Scholar 

  11. Hall KM, Bushnik T, Lakisic-Kazazic B et al (2001) Assessing traumatic brain injury outcome measures for long-term follow-up of community-based individuals. Arch Phys Med Rehabil 82:367–374

    Article  PubMed  CAS  Google Scholar 

  12. Doctor JN, Castro J, Temkin NR et al (2005) Workers’ risk of unemployment after traumatic brain injury: a normed comparison. J Int Neuropsychol Soc 11:747–752

    Article  PubMed  CAS  Google Scholar 

  13. Guilmette TJ, Paglia MF (2004) The public’s misconception about traumatic brain injury: a follow up survey. Arch Clin Neuropsychol 19:183–189

    Article  PubMed  Google Scholar 

  14. Swift TL, Wilson SL (2001) Misconceptions about brain injury among the general public and non-expert health professionals: an exploratory study. Brain Inj 15:149–165

    Article  PubMed  CAS  Google Scholar 

  15. Marr AL, Coronado VG (2002) Central Nervous System Injury Surveillance Data Submission Standards – 2002

    Google Scholar 

  16. Kraus JF, Rice TM, Peek-Asa C et al (2003) Facial trauma and the risk of intracranial injury in motorcycle riders. Ann Emerg Med 41:18–26

    Article  PubMed  Google Scholar 

  17. Johnston JJ (2007) The Galasko report implemented: the role of emergency medicine in the management of head injuries. Eur J Emerg Med 14:130–133

    Article  PubMed  Google Scholar 

  18. Palchak MJ, Holmes JF, Vance CW et al (2003) A decision rule for identifying children at low risk for brain injuries after blunt head trauma. Ann Emerg Med 42:492–506

    Article  PubMed  Google Scholar 

  19. Borg J, Holm L, Cassidy JD et al (2004) Diagnostic procedures in mild traumatic brain injury: results of the WHO Collaborating Centre Task Force on Mild Traumatic Brain Injury. J Rehabil Med (Suppl 43):61–75

    Article  Google Scholar 

  20. Teasdale G, Jennett B (1974) Assessment of coma and impaired consciousness. a practical scale. Lancet 2:81–84

    Article  PubMed  CAS  Google Scholar 

  21. Clifton GL, Hayes RL, Levin HS et al (1992) Outcome measures for clinical trials involving traumatically brain-injured patients: report of a conference. Neurosurgery (Baltim) 31:975–978

    Article  CAS  Google Scholar 

  22. Cowen TD, Meythaler JM, Devivo MJ et al (1995) Influence of early variables in traumatic brain injury on functional independence measure scores and rehabilitation length of stay and charges. Arch Phys Med Rehabil 76:797–803

    Article  PubMed  CAS  Google Scholar 

  23. Gabbe BJ, Cameron PA, Finch CF (2003) The status of the Glasgow Coma Scale. Emerg Med (Fremantle) 15:353–360

    Article  Google Scholar 

  24. Russell WR, Smith A (1961) Post-traumatic amnesia in closed head injury. Arch Neurol 5:4–17

    Article  PubMed  CAS  Google Scholar 

  25. Arciniegas DB, McAllister TW (2008) Neurobehavioral management of traumatic brain injury in the critical care setting. Crit Care Clin 24:viii, 737–viii, 765

    Article  PubMed  Google Scholar 

  26. Levin HS, O’Donnell VM, Grossman RG (1979) The Galveston Orientation and Amnesia Test. A practical scale to assess cognition after head injury. J Nerv Ment Dis 167:675–684

    Article  PubMed  CAS  Google Scholar 

  27. Jackson WT, Novack TA, Dowler RN (1998) Effective serial measurement of cognitive orientation in rehabilitation: the Orientation Log. Arch Phys Med Rehabil 79:718–720

    Article  PubMed  CAS  Google Scholar 

  28. Novack TA, Dowler RN, Bush BA et al (2000) Validity of the Orientation Log, relative to the Galveston Orientation and Amnesia Test. J Head Trauma Rehabil 15:957–961

    Article  PubMed  CAS  Google Scholar 

  29. Frey KL, Rojas DC, Anderson CA et al (2007) Comparison of the O-Log and GOAT as measures of posttraumatic amnesia. Brain Inj 21:513–520

    Article  PubMed  Google Scholar 

  30. Kay T, Harrington DE, Adams RE et al (1993) Definition of mild traumatic brain injury: Report from the Mild Traumatic Brain Injury Committee of the Head Injury Interdisciplinary Special Interest Group of the American Congress of Rehabilitation Medicine. J Head Trauma Rehabil 8:86–87

    Article  Google Scholar 

  31. McMillan TM, Jongen EL, Greenwood RJ (1996) Assessment of post-traumatic amnesia after severe closed head injury: retrospective or prospective? J Neurol Neurosurg Psychiatry 60:422–427

    Article  PubMed  CAS  Google Scholar 

  32. Williams DH, Levin HS, Eisenberg HM (1990) Mild head injury classification. Neurosurgery (Baltim) 27:422–428

    Article  CAS  Google Scholar 

  33. van der Naalt J, Hew JM, van Zomeren AH et al (1999) Computed tomography and magnetic resonance imaging in mild to moderate head injury: early and late imaging related to outcome. Ann Neurol 46:70–78

    Article  PubMed  Google Scholar 

  34. Zafonte RD, Mann NR, Millis SR et al (1997) Posttraumatic amnesia: its relation to functional outcome. Arch Phys Med Rehabil 78:1103–1106

    Article  PubMed  CAS  Google Scholar 

  35. Jennett B, Bond M (1975) Assessment of outcome after severe brain damage. Lancet 1:480–484

    Article  PubMed  CAS  Google Scholar 

  36. Katz DI, Alexander MP (1994) Traumatic brain injury. Predicting course of recovery and outcome for patients admitted to rehabilitation. Arch Neurol 51:661–670

    Article  PubMed  CAS  Google Scholar 

  37. Ellenberg JH, Levin HS, Saydjari C (1996) Posttraumatic amnesia as a predictor of outcome after severe closed head injury. Prospective assessment. Arch Neurol 53:782–791

    Article  PubMed  CAS  Google Scholar 

  38. Brooks DN, Aughton ME, Bond MR et al (1980) Cognitive sequelae in relationship to early indices of severity of brain damage after severe blunt head injury. J Neurol Neurosurg Psychiatry 43:529–534

    Article  PubMed  CAS  Google Scholar 

  39. Geffen GM, Encel JS, Forrester GM (1991) Stages of recovery during post-traumatic amnesia and subsequent everyday memory deficits. NeuroReport 2:105–108

    Article  PubMed  CAS  Google Scholar 

  40. Haslam C, Batchelor J, Fearnside MR et al (1994) Post-coma disturbance and post-traumatic amnesia as nonlinear predictors of cognitive outcome following severe closed head injury: findings from the Westmead Head Injury Project. Brain Inj 8:519–528

    Article  PubMed  CAS  Google Scholar 

  41. Sherer M, Sander AM, Nick TG et al (2002) Early cognitive status and productivity outcome after traumatic brain injury: findings from the TBI model systems. Arch Phys Med Rehabil 83:183–192

    Article  PubMed  Google Scholar 

  42. Avesani R, Salvi L, Rigoli G et al (2005) Reintegration after severe brain injury: a retrospective study. Brain Inj 19:933–939

    Article  PubMed  CAS  Google Scholar 

  43. Doig E, Fleming J, Tooth L (2001) Patterns of community integration 2-5 years post-discharge from brain injury rehabilitation. Brain Inj 15:747–762

    Article  PubMed  CAS  Google Scholar 

  44. Bigler ED (2007) Anterior and middle cranial fossa in traumatic brain injury: relevant neuroanatomy and neuropathology in the study of neuropsychological outcome. Neuropsychology 21:515–531

    Article  PubMed  Google Scholar 

  45. Sabet AA, Christoforou E, Zatlin B et al (2008) Deformation of the human brain induced by mild angular head acceleration. J Biomech 41:307–315

    Article  PubMed  Google Scholar 

  46. Besenski N (2002) Traumatic injuries: imaging of head injuries. Eur Radiol 12:1237–1252

    Article  PubMed  CAS  Google Scholar 

  47. Ryan GA, McLean AJ, Vilenius AT et al (1994) Brain injury patterns in fatally injured pedestrians. J Trauma 36:469–476

    Article  PubMed  CAS  Google Scholar 

  48. Misra JC, Chakravarty S (1984) A study of rotational brain injury. J Biomech 17:459–466

    Article  PubMed  CAS  Google Scholar 

  49. Fijalkowski RJ, Stemper BD, Pintar FA et al (2007) New rat model for diffuse brain injury using coronal plane angular acceleration. J Neurotrauma 24:1387–1398

    Article  PubMed  Google Scholar 

  50. Margulies SS, Thibault LE, Gennarelli TA (1990) Physical model simulations of brain injury in the primate. J Biomech 23:823–836

    Article  PubMed  CAS  Google Scholar 

  51. Meythaler JM, Peduzzi JD, Eleftheriou E et al (2001) Current concepts: diffuse axonal injury-associated traumatic brain injury. Arch Phys Med Rehabil 82:1461–1471

    Article  PubMed  CAS  Google Scholar 

  52. Black KL, Hanks RA, Wood DL et al (2002) Blunt versus penetrating violent traumatic brain injury: frequency and factors associated with secondary conditions and complications. J Head Trauma Rehabil 17:489–496

    Article  PubMed  Google Scholar 

  53. Povlishock JT, Katz DI (2005) Update of neuropathology and neurological recovery after traumatic brain injury. J Head Trauma Rehabil 20:76–94

    Article  PubMed  Google Scholar 

  54. Bigler ED (2003) Neurobiology and neuropathology underlie the neuropsychological deficits associated with traumatic brain injury. Arch Clin Neuropsychol 18:595–621

    PubMed  Google Scholar 

  55. Phillips LL, Reeves TM (2001) Interactive pathology following traumatic brain injury modifies hippocampal plasticity. Restor Neurol Neurosci 19:213–235

    PubMed  CAS  Google Scholar 

  56. Arciniegas DB (2003) The cholinergic hypothesis of cognitive impairment caused by traumatic brain injury. Curr Psychiatry Rep 5:391–399

    Article  PubMed  Google Scholar 

  57. Arciniegas DB, Silver JM (2006) Pharmacotherapy of posttraumatic cognitive impairments. Behav Neurol 17:25–42

    PubMed  Google Scholar 

  58. Markianos M, Seretis A, Kotsou S et al (1992) CSF neurotransmitter metabolites and short-term outcome of patients in coma after head injury. Acta Neurol Scand 86:190–193

    Article  PubMed  CAS  Google Scholar 

  59. Markianos M, Seretis A, Kotsou A et al (1996) CSF neurotransmitter metabolites in comatose head injury patients during changes in their clinical state. Acta Neurochir (Wien ) 138:57–59

    Article  CAS  Google Scholar 

  60. McAllister TW, Flashman LA, Sparling MB et al (2004) Working memory deficits after traumatic brain injury: catecholaminergic mechanisms and prospects for treatment – a review. Brain Inj 18:331–350

    Article  PubMed  Google Scholar 

  61. Povlishock JT (1992) Traumatically induced axonal injury: pathogenesis and pathobiological implications. Brain Pathol 2:1–12

    PubMed  CAS  Google Scholar 

  62. Salmond CH, Chatfield DA, Menon DK et al (2005) Cognitive sequelae of head injury: involvement of basal forebrain and associated structures. Brain 128:189–200

    Article  PubMed  CAS  Google Scholar 

  63. American Psychiatric Association (2000) Diagnostic and Statistical Manual of Mental Disorders, Text Revision, 4th edn. American Psychiatric Association, Washington, DC

    Google Scholar 

  64. Rappaport M (2005) The Disability Rating and Coma/Near-Coma scales in evaluating severe head injury. Neuropsychol Rehabil 15:442–453

    Article  PubMed  Google Scholar 

  65. Trzepacz PT, Mittal D, Torres R et al (2001) Validation of the Delirium Rating Scale-Revised-98: comparison with the delirium rating scale and the cognitive test for delirium. J Neuropsychiatry Clin Neurosci 13:229–242

    Article  PubMed  CAS  Google Scholar 

  66. Sherer M, Nakase-Thompson R, Yablon SA et al (2005) Multidimensional assessment of acute confusion after traumatic brain injury. Arch Phys Med Rehabil 86:896–904

    Article  PubMed  Google Scholar 

  67. Hagen C, Malkmus D, Durham P (1972) Rancho Los Amigos Scale.http://www.rancho.org/patient_education/bi_cognition.pdf

  68. Wortzel HS, Frey KL, Anderson CA, Arciniegas DB (2009). Subtle neurological signs predict the severity of subacute cognitive and functional impairments after traumatic brain injury. J Neuropsychiatry Clin Neurosci 21:463–466

    Google Scholar 

  69. Folstein MF, Folstein SE, McHugh PR (1975) Mini-mental state: a practical method for grading the cognitive state of patients for the clinician. J Psychiatry Res 12:189–198

    Article  CAS  Google Scholar 

  70. Dubois B, Slachevsky A, Litvan I et al (2000) The FAB: a frontal assessment battery at bedside. Neurology 55:1621–1626

    Article  PubMed  CAS  Google Scholar 

  71. Crum RM, Anthony JC, Bassett SS et al (1993) Population-based norms for the mini-mental state examination by age and education level. JAMA 269:2386–2391

    Article  PubMed  CAS  Google Scholar 

  72. Appollonio I, Leone M, Isella V et al (2005) The frontal assessment battery (FAB): normative values in an Italian population sample. Neurol Sci 26:108–116

    Article  PubMed  CAS  Google Scholar 

  73. Arciniegas DB, Frey K, Alderfer B et al (2006) Impairments of frontally-mediated cognition characterize posttraumatic encephalopathy following resolution of posttraumatic amnesia. J Neuropsychiatry Clin Neurosci 18:281

    Article  Google Scholar 

  74. Vanier M, Mazaux JM, Lambert J et al (2000) Assessment of neuropsychologic impairments after head injury: interrater reliability and factorial and criterion validity of the Neurobehavioral Rating Scale – Revised. Arch Phys Med Rehabil 81:796–806

    PubMed  CAS  Google Scholar 

  75. McCauley SR, Levin HS, Vanier M et al (2001) The neurobehavioural rating scale-revised: sensitivity and validity in closed head injury assessment. J Neurol Neurosurg Psychiatry 71:643–651

    Article  PubMed  CAS  Google Scholar 

  76. Royall DR, Mahurin RK, Gray KF (1992) Bedside assessment of executive cognitive impairment: the executive interview. J Am Geriatr Soc 40:1221–1226

    PubMed  CAS  Google Scholar 

  77. Grigsby J, Kaye K, Robbins LJ (1992) Reliabilities, norms and factor structure of the Behavioral Dyscontrol Scale. Percept Mot Skills 74:883–892

    Article  PubMed  CAS  Google Scholar 

  78. Kaye K, Grigsby J, Robbins LJ et al (1990) Prediction of independent functioning and behavior problems in geriatric patients. J Am Geriatr Soc 38:1304–1310

    PubMed  CAS  Google Scholar 

  79. Cummings JL, Mega M, Gray K et al (1994) The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology 44:2308–2314

    Article  PubMed  CAS  Google Scholar 

  80. Kalmar K, Novack TA, Nakase-Richardson R et al (2008) Feasibility of a brief neuropsychologic test battery during acute inpatient rehabilitation after traumatic brain injury. Arch Phys Med Rehabil 89:942–949

    Article  PubMed  Google Scholar 

  81. Hanks RA, Millis SR, Ricker JH et al (2008) The predictive validity of a brief inpatient neuropsychologic battery for persons with traumatic brain injury. Arch Phys Med Rehabil 89:950–957

    Article  PubMed  Google Scholar 

  82. Akiyama Y, Miyata K, Harada K et al (2009) Susceptibility-weighted magnetic resonance imaging for the detection of cerebral microhemorrhage in patients with traumatic brain injury. Neurol Med Chir (Tokyo) 49:97–99

    Article  Google Scholar 

  83. Arciniegas DB, Anderson CA, Rojas DC (2005) Electrophysiological techniques. In: Silver JM, McAllister TW, Yudofsky SC (eds) Textbook of traumatic brain injury. American Psychiatric Publishing, Washington, DC

    Google Scholar 

  84. Rothman MS, Arciniegas DB, Filley CM et al (2007) The neuroendocrine effects of traumatic brain injury. J Neuropsychiatry Clin Neurosci 19:363–372

    Article  PubMed  CAS  Google Scholar 

  85. Frey LC (2003) Epidemiology of posttraumatic epilepsy: a critical review. Epilepsia 44(suppl 10):11–17

    Article  PubMed  Google Scholar 

  86. Schierhout G, Roberts I (2000) Anti-epileptic drugs for preventing seizures following acute traumatic brain injury. Cochrane Database Syst Rev 4:CD000173

    Google Scholar 

  87. Dikmen SS, Temkin NR, Miller B et al (1991) Neurobehavioral effects of phenytoin prophylaxis of posttraumatic seizures. JAMA 265:1271–1277

    Article  PubMed  CAS  Google Scholar 

  88. Smith KR Jr, Goulding PM, Wilderman D et al (1994) Neurobehavioral effects of phenytoin and carbamazepine in patients recovering from brain trauma: a comparative study. Arch Neurol 51:653–660

    Article  PubMed  Google Scholar 

  89. Szaflarski JP, Meckler JM, Szaflarski M et al (2007) Levetiracetam use in critically ill patients. Neurocrit Care 7:140–147

    Article  PubMed  Google Scholar 

  90. Ruegg S, Naegelin Y, Hardmeier M et al (2008) Intravenous levetiracetam: treatment experience with the first 50 critically ill patients. Epilepsy Behav 12:477–480

    Article  PubMed  Google Scholar 

  91. Mula M, Trimble MR, Yuen A et al (2003) Psychiatric adverse events during levetiracetam therapy. Neurology 61:704–706

    Article  PubMed  CAS  Google Scholar 

  92. Mula M, Trimble MR, Sander JW (2004) Psychiatric adverse events in patients with epilepsy and learning disabilities taking levetiracetam. Seizure 13:55–57

    Article  PubMed  Google Scholar 

  93. Dikmen SS, Machamer JE, Winn HR et al (2000) Neuropsychological effects of valproate in traumatic brain injury: a randomized trial. Neurology 54:895–902

    Article  PubMed  CAS  Google Scholar 

  94. Marion DW (2006) Evidenced-based guidelines for traumatic brain injuries. Prog Neurol Surg 19:171–196

    Article  PubMed  Google Scholar 

  95. Fugate LP, Spacek LA, Kresty LA et al (1997) Measurement and treatment of agitation following traumatic brain injury: II. A survey of the Brain Injury Special Interest Group of the American Academy of Physical Medicine and Rehabilitation. Arch Phys Med Rehabil 78:924–928

    Article  PubMed  CAS  Google Scholar 

  96. Milbrandt EB, Kersten A, Kong L et al (2005) Haloperidol use is associated with lower hospital mortality in mechanically ventilated patients. Crit Care Med 33:226–229

    Article  PubMed  CAS  Google Scholar 

  97. Goldstein LB (1993) Basic and clinical studies of pharmacologic effects on recovery from brain injury. J Neural Transplant Plast 4:175–192

    Article  PubMed  CAS  Google Scholar 

  98. Goldstein LB (1999) Pharmacological approach to functional reorganization: the role of norepinephrine. Rev Neurol (Paris) 155:731–736

    CAS  Google Scholar 

  99. Goldstein LB (2003) Neuropharmacology of TBI-induced plasticity. Brain Inj 17:685–694

    Article  PubMed  Google Scholar 

  100. Goldstein LB (2006) Neurotransmitters and motor activity: effects on functional recovery after brain injury. NeuroRx 3:451–457

    Article  PubMed  CAS  Google Scholar 

  101. Hoffman AN, Cheng JP, Zafonte RD et al (2008) Administration of haloperidol and risperidone after neurobehavioral testing hinders the recovery of traumatic brain injury-induced deficits. Life Sci 83:602–607

    Article  PubMed  CAS  Google Scholar 

  102. Kline AE, Hoffman AN, Cheng JP et al (2008) Chronic administration of antipsychotics impede behavioral recovery after experimental traumatic brain injury. Neurosci Lett 448:263–267

    Article  PubMed  CAS  Google Scholar 

  103. Kline AE, Massucci JL, Zafonte RD et al (2007) Differential effects of single versus multiple administrations of haloperidol and risperidone on functional outcome after experimental brain trauma. Crit Care Med 35:919–924

    Article  PubMed  CAS  Google Scholar 

  104. Stanislav SW (1997) Cognitive effects of antipsychotic agents in persons with traumatic brain injury. Brain Inj 11:335–341

    Article  PubMed  CAS  Google Scholar 

  105. Rao N, Jellinek HM, Woolston DC (1985) Agitation in closed head injury: haloperidol effects on rehabilitation outcome. Arch Phys Med Rehabil 66:30–34

    PubMed  CAS  Google Scholar 

  106. Buffett-Jerrott SE, Stewart SH (2002) Cognitive and sedative effects of benzodiazepine use. Curr Pharm Des 8:45–58

    Article  PubMed  CAS  Google Scholar 

  107. Bleiberg J, Garmoe W, Cederquist J et al (1993) Effects of dexedrine on performance consistency following brain injury: a double-blind placebo crossover case study. Neuropsychiatry Neuropsychol Behav Neurol 6:245–248

    Google Scholar 

  108. Schmitt JA, Kruizinga MJ, Riedel WJ (2001) Non-serotonergic pharmacological profiles and associated cognitive effects of serotonin reuptake inhibitors. J Psychopharmacol 15:173–179

    Article  PubMed  CAS  Google Scholar 

  109. McCarter RJ, Walton NH, Moore C et al (2007) PTA testing, the Westmead post traumatic amnesia scale and opiate analgesia: a cautionary note. Brain Inj 21:1393–1397

    Article  PubMed  CAS  Google Scholar 

  110. Warden DL, Gordon B, McAllister TW et al (2006) Guidelines for the pharmacologic treatment of neurobehavioral sequelae of traumatic brain injury. J Neurotrauma 23:1468–1501

    Article  PubMed  Google Scholar 

  111. Cicerone KD, Dahlberg C, Kalmar K et al (2000) Evidence-based cognitive rehabilitation: recommendations for clinical practice. Arch Phys Med Rehabil 81:1596–1615

    Article  PubMed  CAS  Google Scholar 

  112. Cicerone KD, Dahlberg C, Malec JF et al (2005) Evidence-based cognitive rehabilitation: updated review of the literature from 1998 through 2002. Arch Phys Med Rehabil 86:1681–1692

    Article  PubMed  Google Scholar 

  113. Cappa SF, Benke T, Clarke S et al (2005) EFNS guidelines on cognitive rehabilitation: report of an EFNS task force. Eur J Neurol 12:665–680

    Article  PubMed  CAS  Google Scholar 

  114. Cappa SF, Benke T, Clarke S et al (2003) EFNS guidelines on cognitive rehabilitation: report of an EFNS task force. Eur J Neurol 10:11–23

    Article  PubMed  CAS  Google Scholar 

  115. Tate RL, Moseley A, Perdices M et al (2006) Update on Cicerone’s systematic review of cognitive rehabilitation: the PsycBITE perspective. Arch Phys Med Rehabil 87:446

    Article  PubMed  Google Scholar 

  116. Cicerone KD, Mott T, Azulay J et al (2008) A randomized controlled trial of holistic neuropsychologic rehabilitation after traumatic brain injury. Arch Phys Med Rehabil 89:2239–2249

    Article  PubMed  Google Scholar 

  117. Cicerone KD, Mott T, Azulay J et al (2004) Community integration and satisfaction with functioning after intensive cognitive rehabilitation for traumatic brain injury. Arch Phys Med Rehabil 85:943–950

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to David B Arciniegas .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer

About this chapter

Cite this chapter

Arciniegas, D.B. (2010). Neuropsychiatric Assessment of Traumatic Brain Injury During Acute Neurorehabilitation* . In: Miyoshi, K., Morimura, Y., Maeda, K. (eds) Neuropsychiatric Disorders. Springer, Tokyo. https://doi.org/10.1007/978-4-431-53871-4_10

Download citation

  • DOI: https://doi.org/10.1007/978-4-431-53871-4_10

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-53870-7

  • Online ISBN: 978-4-431-53871-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics