Abstract
Hypospadias is one of the most common urogenital anomalies, occurring in about 3 per 1,000 male births. The heritability of the condition is well recognised, and empiric recurrence risks suggest that brothers of an affected individual have a 6–17% chance of also being affected (Angerpointer 1984; Stoll et al. 1990). Data regarding the offspring risk for an affected father are scanty but one study has indicated that the incidence of hypospadias among fathers of affected boys is increased fivefold (Angerpointer 1984).
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Whiteford, M. (2004). Genetic Aspects of Hypospadias. In: Hadidi, A.T., Azmy, A.F. (eds) Hypospadias Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07841-9_4
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DOI: https://doi.org/10.1007/978-3-662-07841-9_4
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