Abstract
The purpose of this study was to evaluate the diagnostic accuracy of contrast-enhanced endorectal MRI for the staging of rectal adenoma versus rectal carcinoma in correlation to findings from biopsy and histopathology.
Ten volunteers and 20 patients underwent body-coil and endorectal MRI (1.5 T supraconducting unit) using plain, Tl-weighted (w) T2-w SE and TSEw sequences, a dynamic Gd-DTPA enhanced protocol (turboFLASH), and postcontrast Tl-w-SE sequences. Histopathological correlation via biopsy (n = 10) and surgical resection (n = 19) were conducted for all patients. An independent, two-observer, reader evaluation was performed and qualitative and quantitative data calculated.
In volunteers and all patients endorectal MRI reliably delineatel normal wall layers. Rectal adenomas (n = 7) were identified by a visualization of an intact muscularis mucosae, a homogeneous inner structure, and a significant contrast enhancement. T1 carcinomas (n = 4) were best identified in dynamic turboFLASH sequences by delineation of an intact muscularis propria. The visualization of contrast-enhancing tumor tissue was indicative of a T2 carcinoma (n = 4). All T3 (n = 3) and T4 (n = 2) carcinomas were correctly staged on dynamic and static MRI. The endorectal MRI stage agreed with the staging results from pathological study in 16 of 20 (80%) patients.
Endorectal surface coil MRI provides reliable data for the preoperative staging and evaluation of rectal lesions.
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© 1996 Springer-Verlag Berlin Heidelberg
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Vogl, T.J. et al. (1996). Radiological Modalities in the Staging of Colorectal Tumors: New Perspectives for Increasing Accuracy. In: Kreuser, ED., Schlag, P.M. (eds) New Perspectives in Molecular and Clinical Management of Gastrointestinal Tumors. Recent Results in Cancer Research, vol 142. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80035-1_8
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DOI: https://doi.org/10.1007/978-3-642-80035-1_8
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