Skip to main content

Intrapericardial Treatment in Pericardial Disease

  • Chapter
Interventional Pericardiology

Abstract

Independent of the etiology of the underlying disease the intrapericardial application of drugs offers the advantage that a high local dose can be applied with little systemic side effects. The pericardial sac is, similarly as the pleural space, a nearly ideal compartment for such an application with a very limited exchange of its content to the systemic circulation or other organs.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Mukai K, Shinkai T, Tominaga K, Shimosatto Y. The incidence of secondary tumors of the heart and pericardium: A 10 year study. Jpn J Clin Oncol 1988; 18(3): 195–201

    PubMed  CAS  Google Scholar 

  2. Posner MR, Cohen GI, Skarin AT. Pericardial disease in patients with cancer. Am J Med 1981; 71(3): 407–413

    Article  PubMed  CAS  Google Scholar 

  3. Maisch B, Ristić AD, Pankuweit S, Neubauer A, Moll R. Neoplastic pericardial effusion. Efficacy and safety of intrapericardial treatment with cisplatin. Eur Heart J 2002; 23(20): 1625–1631

    Article  PubMed  CAS  Google Scholar 

  4. Wilding G, Green HL, Longo DL, Urba WJ. Tumors of the heart and pericardium. Cancer Treat Rev 1988; 15: 165–181

    Article  PubMed  CAS  Google Scholar 

  5. Spodick DH. Pericardial diseases. In: Braunwald E, Zipes DP, Libby P (eds) Heart Disease, 6th ed. W.B. Saunders, Philadelphia, PA, 2001, pp 1823–1876

    Google Scholar 

  6. Ziskind AA, Palacios IF. Percutaneous balloon pericardiotomy for patients with pericardial effusion and tamponade. In: Topol EJ (ed) Textbook of Interventional Cardiology, 3rd edn. W.B. Saunders, Philadelphia, PA, 1999, pp 869–877

    Google Scholar 

  7. Ristić AD, Seferović PM, Maksimović R, Ostojić M. Percutaneous balloon pericardiotomy in neoplastic pericardial effusion. In: Seferović PM, Spodick DH, Maisch B. (eds) Pericardiology: Contemporary answers to continuing challenges. Science, Belgrade, 2000, pp 427–438

    Google Scholar 

  8. Aitini E, Cavazzini G, Pasquini E, et al. Treatment of primary or metastatic pleural effusion with intracavitary cytosine arabinoside and cisplatin. A phase II study. Acta Oncol 1994; 33(2): 191–194

    Article  PubMed  CAS  Google Scholar 

  9. Bindi M, Trusso M, Tucci E. Intracavitary cisplatin in malignant cardiac tamponade. Tumori 1987; 73(2): 163–165

    PubMed  CAS  Google Scholar 

  10. Pavon-Jimenez R, Garcia-Rubira JC, Garcia-Martinez JT, Sanchez-Escribano R, Calvo-Jambrina R, Cruz-Fernandez JM. Intrapericardial cisplatin for malignant tamponade. Rev Esp Cardiol 2000; 53(4): 587–589

    PubMed  CAS  Google Scholar 

  11. Tomkowski W, Szturmowicz M, Fijalkowska A, Filipecki S, Figura-Chojak E. Intrapericardial cisplatin for the management of patients with large malignant pericardial effusion. J Cancer Res Clin Oncol 1994; 120(7): 434–436

    Article  PubMed  CAS  Google Scholar 

  12. Tomkowski WZ, Filipecki S. Intrapericardial cisplatin for the management of patients with large malignant pericardial effusion in the course of the lung cancer. Lung Cancer 1997; 16(2–3): 215–222

    Article  PubMed  CAS  Google Scholar 

  13. Tomkowski WZ, Filipecki S. Intrapericardial administration of cisplatin in treatment of metastatic pericardial involvement in adenocarcinoma of the lung. Arch Chest Dis 1997; 52: 221–224

    CAS  Google Scholar 

  14. Tomkowski W, Szturmowicz M, Fijalkowska A, Burakowski J, Filipecki S. New approaches to the management and treatment of malignant pericardial effusion. Support Care Cancer 1997; 5(1): 64–66

    Article  PubMed  CAS  Google Scholar 

  15. Fiorentino MV, Daniele O, Morandi P, et al. Intrapericardial instillation of platin in malignant pericardial effusion. Cancer 1988; 62(9): 1904–1906

    Article  PubMed  CAS  Google Scholar 

  16. Tondini M, Rocco G, Bianchi C, Severi C, Corbellini D. Intracavitary cisplatin (CDDP) in the treatment of metastatic pericardial involvement from breast and lung cancer. Monaldi Arch Chest Dis 1995; 50(2): 86–88

    PubMed  CAS  Google Scholar 

  17. Lestuzzi Ch, Viel E, Sorio R, Meneguzzo N. Local chemotherapy for neoplastic pericardial effusion [letter]. Am J Cardiol 2000; 86: 1292

    Article  PubMed  CAS  Google Scholar 

  18. Beretta F, Martinelli G, Cavalli F, Marone C. Pericardial effusion in patients with malignant neoplasms. Schweiz Med Wochenschr 1992; 122: 1517–1524

    PubMed  CAS  Google Scholar 

  19. Bishiniotis TS, Antoniadou S, Katseas G, Mouratidou D, Litos AG, Balamoutsos N. Malignant cardiac tamponade in women with breast cancer treated by pericardiocentesis and intrapericardial administration of triethylenethiophosphoramide (thiotepa). Am J Cardiol 2000; 86(3): 362–364

    Article  PubMed  CAS  Google Scholar 

  20. Colleoni M, Martinelli G, Beretta F, et al. Intracavitary chemotherapy with thiotepa in malignant pericardial effusions: an active and well-tolerated regimen. J Clin Oncol 1998; 16: 2371–2376

    PubMed  CAS  Google Scholar 

  21. Girardi LN, Ginsberg RJ, Burt ME. Pericardiocentesis and intrapericardial sclerosis: effective therapy for malignant pericardial effusions. Ann Thorac Surg 1997; 64(5): 1422–1447

    Article  PubMed  CAS  Google Scholar 

  22. Martinoni A, Cipolla CM, Civelli M, et al. Intrapericardial treatment of neoplastic pericardial effusions. Herz 2000; 25(8): 787–793

    Article  PubMed  CAS  Google Scholar 

  23. Fukuoka M, Takada M, Tamai S, et al. Local application of anti-cancer drugs for the treatment of malignant pleural and pericardial effusion. Gan To Kagaku Ryoho 1984; 11(8): 1543–1549

    PubMed  CAS  Google Scholar 

  24. Thai V, Oneschuk D. Malignant pericardial effusion treated with intrapericardial bleomycin. J Palliat Med 2007; 10(2): 281–282

    Article  PubMed  Google Scholar 

  25. Kaira K, Mori M. Intrapericardial instillation of mitomycin C in recurrent cardiac tamponade due to malignant pericardial effusion. Clin Oncol (R Coll Radiol) 2006; 18(6): 506

    Article  CAS  Google Scholar 

  26. Bischiniotis TS, Lafaras CT, Platogiannis DN, Moldovan L, Barbetakis NG, Katseas GP. Intrapericardial cisplatin administration after pericardiocentesis in patients with lung adenocarcinoma and malignant cardiac tamponade. Hellenic J Cardiol 2005; 46(5): 324–329

    PubMed  Google Scholar 

  27. Martinoni A, Cipolla CM, Cardinale D, Civelli M, Lamantia G, Colleoni M, Fiorentini C. Long-term results of intrapericardial chemotherapeutic treatment of malignant pericardial effusions with thiotepa. Chest 2004; 126(5): 1412–1416

    Article  PubMed  Google Scholar 

  28. Lissoni P, Barni S, Tancini G, et al. Intracavitary therapy of neoplastic effusions with cytokines: comparison among interferon alpha, beta and interleukin-2. Support Care Cancer 1995; 3(1): 78–80

    Article  PubMed  CAS  Google Scholar 

  29. Imamura T, Tamura K, Takenaga M, Nagamoto Y, Ishikawa T, Nakagawa S. Intrapericardial OK-432 instillation for the management of malignant pericardial effusion. Cancer 1991; 68: 259–263

    Article  PubMed  CAS  Google Scholar 

  30. Liu G, Crump M, Goss PE, Dancey J, Shepherd FA. Prospective comparison of the sclerosing agents doxycycline and bleomycin for the primary management of malignant pericardial effusion and cardiac tamponade. J Clin Oncol 1996; 14(12): 3141–3147

    PubMed  CAS  Google Scholar 

  31. Van Der Gaast A, Kok TC, Van Der Linden NH, Splinter TA. Intrapericardial instillation of bleomycin in the management of malignant pericardial effusion. Eur J Cancer Clin Oncol 1989; 25(10): 1505–1506

    Article  PubMed  Google Scholar 

  32. Yano T, Yokoyama H, Inoue T, Takanashi N, Asoh H, Ichinose Y. A simple technique to manage malignant pericardial effusion with a local instillation of bleomycin in non-small cell carcinoma of the lung. Oncology 1994; 51(6): 507–509

    Article  PubMed  CAS  Google Scholar 

  33. Cormican MC, Nyman CR. Intrapericardial bleomycin for the management of cardiac tamponade secondary to malignant pericardial effusion. Br Heart J 1990; 63: 61–62

    Article  PubMed  CAS  Google Scholar 

  34. Kohnoe S, Maehara Y, Takahashi I, et al. Intrapericardial mitomycin C for the management of malignant pericardial effusion secondary to gastric cancer: case report and review. Chemotherapy 1994; 40: 57–60

    Article  PubMed  CAS  Google Scholar 

  35. Lee LN, Yang PC, Chang DB, et al. Ultrasound guided pericardial drainage and intrapericardial instillation of mitomycin C for malignant pericardial effusion. Thorax 1994; 49(6): 594–595

    Article  PubMed  CAS  Google Scholar 

  36. Grau JJ, Estape J, Palombo H, et al. Intracavitary oxytetracycline in malignant pericardial tamponade. Oncology 1992; 49: 489–491

    Article  PubMed  CAS  Google Scholar 

  37. Davis S, Rambotti P, Grignani F. Intrapericardial tetracycline sclerosis in the treatment of malignant pericardial effusion: an analysis of thirty-three cases. J Clin Oncol 1984; 2(6): 631–636

    PubMed  CAS  Google Scholar 

  38. Maher EA, Shepherd FA, Todd TJ. Pericardial sclerosis as the primary management of malignant pericardial effusion and cardiac tamponade. J Thorac Cardiovasc Surg 1996; 112(3): 637–643

    Article  PubMed  CAS  Google Scholar 

  39. Salamon P, Berliner S, Shachner A, Pinkhas J. Tetracycline treatment for malignant pericardial effusion. Med Interne 1989; 27(1): 73–74

    PubMed  CAS  Google Scholar 

  40. Shepherd FA, Ginsberg JS, Evans WK, Scott JG, Oleksiuk F. Tetracycline sclerosis in the management of malignant pericardial effusion. J Clin Oncol 1985; 3(12): 1678–1682

    PubMed  CAS  Google Scholar 

  41. Shepherd FA, Morgan C, Evans WK, Ginsberg JF, Watt D, Murphy K. Medical management of malignant pericardial effusion by tetracycline sclerosis. Am J Cardiol 1987; 60: 1161–1166

    Article  PubMed  CAS  Google Scholar 

  42. Musch E, Gremmler B, Nitsch J, Rieger J, Malek M, Chrissafidou A. Intrapericardial instillation of mitoxantrone in palliative therapy of malignant pericardial effusion. Onkologie 2003; 26: 135–139

    Article  PubMed  CAS  Google Scholar 

  43. Norum J, Lunde P, Aasebo U, Himmelmann A. Mitoxantrone in malignant pericardial effusion. J Chemother 1998; 10(5): 399–404

    PubMed  CAS  Google Scholar 

  44. Ammon A, Eiffert H, Reil S, Beyer JH, Droese M, Hiddemann W. Tumor-associated antigens in effusions of malignant and benign origin. Clin Investig 1993; 71(6): 437–444

    Article  PubMed  CAS  Google Scholar 

  45. Kuhn K, Purea H, Selbach J, Westerhausen M. Treatment with locally applied mitoxantrone. Acta Med Austriaca 1989; 16(3–4): 87–90

    PubMed  CAS  Google Scholar 

  46. Toh U, Fujii T, Seki N, Niiya F, Shirouzu K, Yamana H. Characterization of IL-2-activated TILs and their use in intrapericardial immunotherapy in malignant pericardial effusion. Cancer Immunol Immunother 2006; 55(10): 1219–1227

    Article  PubMed  CAS  Google Scholar 

  47. Nanjo T. Intracavitary injection of OK-432 for malignant pericardial effusion, a case report. Radiat Med 1990; 8(4): 155–158

    PubMed  CAS  Google Scholar 

  48. Imamura T, Tamura K, Taguchi T, Makino S, Seita M. Intrapericardial instillation of OK-432 for the management of malignant pericardial effusion: report of three cases. Jpn J Med 1989; 28(1): 62–66

    Article  PubMed  CAS  Google Scholar 

  49. Wakiyama S, Shirabe K, Nagaie T. A case of carcinomatous cardiac tamponade due to breast cancer treated with OK-432 and mitomycin C. Gan To Kagaku Ryoho 2007; 34(3): 439–441

    PubMed  Google Scholar 

  50. Furukawa A, Itoh A, Nakamura T, et al. Efficacy of percutaneous balloon pericardiotomy and intrapericardial instillation for the management of refractory pericardial effusion: a case report. J Cardiol 2007; 50(6): 389–395

    PubMed  Google Scholar 

  51. Tomkowski WZ, Wiśniewska J, Szturmowicz M, et al. Evaluation of intrapericardial cisplatin administration in cases with recurrent malignant pericardial effusion and cardiac tamponade. Support Care Cancer 2004; 12(1): 53–57

    Article  PubMed  Google Scholar 

  52. Ultmann JE, Hyman GA, Grandall C, et al. Triethylenethiophosphoramide (thiotepa) in the treatment of neoplastic disease. Cancer 1957; 19: 902–910

    Article  Google Scholar 

  53. Anderson CB, Philpott GW, Ferguson TB. The treatment of malignant pleural effusions. Cancer 1974; 33: 916–922

    Article  PubMed  CAS  Google Scholar 

  54. Koontz WW, Prout GR, Smith W, et al. The use of intravesical thiotepa in the management of non-invasive carcinoma of the bladder. J Urol 1981; 125: 307–312

    PubMed  Google Scholar 

  55. De Kock mlS, Breytenbach IH. Local excision and topical thiotepa in the treatment of transitional cell carcinoma of the renal perlvis: a case report. J Urol 1986; 135: 566–567

    PubMed  Google Scholar 

  56. van Belle SJ, Volckaert A, Taeymans Y, Spapen H, Block P. Treatment of malignant pericardial tamponade with sclerosis induced by instillation of bleomycin. Int J Cardiol 1987; 16(2): 155–160

    Article  PubMed  Google Scholar 

  57. Kawashima O, Kurihara T, Kamiyoshihara M, Sakata S, Ishikawa S, Morishita Y. Management of malignant pericardial effusion resulting from recurrent cancer with local instillation of aclarubicin hydrochloride. Am J Clin Oncol 1999; 22(4): 396–398

    Article  PubMed  CAS  Google Scholar 

  58. Celermajer DS, Boyer MJ, Bailey BP, Tattersall MH. Pericardiocentesis for symptomatic malignant pericardial effusion: a study of 36 patients. Med J Aust 1991; 154(1): 19–22

    PubMed  CAS  Google Scholar 

  59. Lashevsky I, Ben Yosef R, Rinkevich D, Reisner S, Markiewicz W. Intrapericardial minocycline sclerosis for malignant pericardial effusion. Chest 1996; 109(6): 1452–1454

    Article  PubMed  CAS  Google Scholar 

  60. Markiewicz W, Lashevsky I, Rinkevich D, Teitelman U, Reisner SA. The acute effect of minocycline on the pericardium: experimental and clinical findings. Chest 1998; 113(4): 861–866

    Article  PubMed  CAS  Google Scholar 

  61. Markiewicz W, Ben-Arieh Y, Best L, et al. The effect of Minocin on the pericardium. Oncology 1993; 50: 478–482

    Article  PubMed  CAS  Google Scholar 

  62. Ehninger G, Proksch B, Heinzel G, Schiller E, Weible KH, Woodward DL. The pharmacokinetics and metabolism of mitoxantrone in man. Invest New Drugs 1985; 3: 109–116

    Article  PubMed  CAS  Google Scholar 

  63. Lentsch S, Reichardt P, Gürtler R, Dörken B. Intrapericardial application of mitoxantrone for treatment of malignant pericardial effusion. Onkologie 1994; 17: 504–507

    Article  Google Scholar 

  64. Hoffmann W, Reichel H, Schiebe M, Bültmann B, Bamberg M. Intrapericardial instillation of mitoxantrone in malignant pericarditis: Histomorphological appearance. Reg Cancer Treat 1993; 2: 91–93

    Google Scholar 

  65. Ammon J, Icking D, Sigmund M, Zimmermann U. Intraperikardiale Instillation von Mitoxantron bei malignen Perikardergüssen. In: Musch E, Dietel M, Schenk S (Hrsg) Aktuelle Onkologie 54. Zuckschwerdt, München, 1990, S 70–84

    Google Scholar 

  66. Toh U, Yamana H, Sueyoshi S, et al. Locoregional cellular immunotherapy for patients with advanced esophageal cancer. Clin Cancer Res 2000; 6: 4663–4673

    PubMed  CAS  Google Scholar 

  67. Toh U, Sudo T, Kido K, et al. Locoregional adoptive immunotherapy resulted in regression in distant metastases of a recurrent esophageal cancer. Int J Clin Oncol 2002; 7: 372–375

    Article  PubMed  Google Scholar 

  68. Tulleken JE, Kooiman CG, Van Der Werf TS, Zijlstra JG, de Vries EG. Constrictive pericarditis after high-dose chemotherapy. Lancet 1997; 350(9091): 1601

    Article  PubMed  CAS  Google Scholar 

  69. Kahles H, Bastian HJ, Schiffmann O, Geck M, Helmke FR, Golz N. Mitoxantrone-induced acute left heart failure after intrapleural administration. Herz 1997; 22(4): 217–220

    Article  PubMed  CAS  Google Scholar 

  70. Permanyer-Miralda G, Sagrista-Sauleda J, Soler-Soler J. Primary acute pericardial disease: A prospective series of 231 consecutive patients. Am J Cardiol 1985; 56: 623–630

    Article  PubMed  CAS  Google Scholar 

  71. Sagrista-Sauleda J, Angel J, Permanyer-Miralda G, Soler-Soler J. Long-term follow-up of idiopathic chronic pericardial effusion. N Engl J Med 1999; 341: 2054–2059

    Article  PubMed  CAS  Google Scholar 

  72. Maisch B, Pankuweit S, Brilla C, et al. Intrapericardial treatment of inflammatory and neoplastic pericarditis guided by pericardioscopy and epicardial biopsy - results from a pilot study. Clin Cardiol 1999; 22(suppl 1): I17–22

    Article  PubMed  CAS  Google Scholar 

  73. Maisch B, Bethge C, Drude L, Hufnagel G, Herzum M, Schönian U. Pericardioscopy and epicardial biopsy-new diagnostic tools in pericardial and perimyocardial disease. Eur Heart J 1994; 15 (Suppl C): 68–73

    PubMed  Google Scholar 

  74. Maisch B, Ristic AD, Pankuweit S. Intrapericardial treatment of autoreactive pericardial effusion with triamcinolone: the way to avoid side effects of systemic corticosteroid therapy. Eur Heart J 2002; 23: 1503–1508

    Article  PubMed  CAS  Google Scholar 

  75. Adler Y, Finkelstein Y, Guindo J, et al. Colchicine treatment for recurrent pericarditis. A decade of experience. Circulation 1998; 97: 2183–2185

    PubMed  CAS  Google Scholar 

  76. Markel G, Imazio M, Brucato A, Adler Y. Colchicine for the prevention of recurrent pericarditis. Isr Med Assoc J 2008; 10(1): 69–72

    PubMed  Google Scholar 

  77. Imazio M, Bobbio M, Cecchi E, et al. Colchicine as firstchoice therapy for recurrent pericarditis: results of the CORE (COlchicine for REcurrent pericarditis) trial. Arch Intern Med 2005; 165(17): 1987–1991

    Article  PubMed  CAS  Google Scholar 

  78. Buselmeier TJ, Davin TD, Simmons RL, Najarian JS, Kjellstrand CM. Treatment of intractable uremic pericardial effusion. Avoidance of pericardiectomy with local steroid instillation. JAMA 1978; 240(13): 1358–1359

    Article  PubMed  CAS  Google Scholar 

  79. Fuller TJ, Knochel JP, Brennan JP, Fetner CD, White mg. Reversal of intractable uremic pericarditis by triamcinolone hexacetonide. Arch Intern Med 1976; 136(9): 979–982

    Article  PubMed  CAS  Google Scholar 

  80. Quigg RJ Jr, Idelson BA, Yoburn DC, Hymes JL, Schick EC, Bernard DB. Local steroids in dialysis-associated pericardial effusion. A single intrapericardial administration of triamcinolone. Arch Intern Med 1985; 145(12): 2249–2250

    Article  PubMed  Google Scholar 

  81. Popli S, Ing TS, Daugirdas JT, et al. Treatment of uremic pericardial effusion by local steroid instillation via subxiphoid pericardiotomy. J Dial 1980; 4(2–3): 83–89

    PubMed  CAS  Google Scholar 

  82. Kristal B, Shasha SM, Mahmoud H, Stamler B. Management of uremic pericarditis. Isr J Med Sci 1986; 22(6): 442–444 83. Spodick DH. Chronic tuberculous and other granulomatous pericariditis. In: Spodick DH. Chronic and constrictive pericarditis. Grune & Stratton, New York, 1964, p 34

    PubMed  CAS  Google Scholar 

  83. Spodick DH. Chronic tuberculous and other granulomatous pericariditis. In: Spodick DH. Chronic and constrictive pericarditis. Grune & Stratton, New York, 1964, p 34

    Google Scholar 

  84. Zeman RK, Scovern H. Intrapericardial steroids in treatment of rheumatoid pericardial tamponade [letter]. Arthritis Rheum 1977; 20(6): 1289–1290

    Article  PubMed  CAS  Google Scholar 

  85. Feinroth MV, Goldstein EJ, Josephson A, Friedman EA. Infection complicating intrapericardial steroid instillation in uremic pericarditis. Clin Nephrol 1981; 15(6): 331–333

    PubMed  CAS  Google Scholar 

  86. Brumund MR, Truemper EJ, Lutin WA, Pearson-Shaver AL. Disseminated varicella and staphylococcal pericarditis after topical steroids. J Pediatr 1997; 131(1): 162–163

    Article  PubMed  CAS  Google Scholar 

  87. Silverstein R, Crumbo D, Long DL, Kokko JP, Hull AR, Vergne-Marini P. Iatrogenic arteriovenous fistula. An unusual complication of indwelling pericardial catheter and intrapericardial steroid instillation for the treatment of uremic pericarditis. Arch Intern Med 1978; 138(2): 308–310

    Article  PubMed  CAS  Google Scholar 

  88. Grubb SR, Cantley LK, Jones DL, Carter WH. Iatrogenic Cushing’s syndrome after intrapericardial corticosteroid therapy. Ann Intern Med 1981; 95(6): 706–707

    PubMed  CAS  Google Scholar 

  89. Rostand SG, Rutsky EA. Pericarditis in end-stage renal disease. Cardiol Clin 1990; 8: 701–706

    PubMed  CAS  Google Scholar 

  90. Gunukula SR, Spodick DH. Pericardial disease in renal patients. Semin Nephrol 2001; 21: 52–57

    Article  PubMed  CAS  Google Scholar 

  91. Tarng DC, Huang TP. Uraemic pericarditis: a reversible inflammatory state of resistance to recombinant human erythropoietin in haemodialysis patients. Nephrol Dial Transplant 1997; 12: 1051–1057

    Article  PubMed  CAS  Google Scholar 

  92. Spaia S, Patsalas S, Agelou A, et al. Managing refractory uraemic pericarditis with colchicine. Nephrol Dial Transplant 2004; 19(9): 2422–2423

    Article  PubMed  CAS  Google Scholar 

  93. Peraino RA. Pericardial effusion in patients treated with maintenance dialysis. Am J Nephrol 1983; 3(6): 319–322

    Article  PubMed  CAS  Google Scholar 

  94. Medani CR, Ringel RE. Intrapericardial triamcinolone hexacetonide in the treatment of intractable uremic pericarditis in a child. Pediatr Nephrol 1988; 2(1): 32–33

    Article  PubMed  CAS  Google Scholar 

  95. Daugirdas JT, Leehey DJ, Popli S, et al. Subxiphoid pericardiostomy for hemodialysis-associated pericardial effusion. Arch Intern Med 1986; 146(6): 1113–1115

    Article  PubMed  CAS  Google Scholar 

  96. Pankuweit S, Ristić AD, Seferović PM, Maisch B. Bacterial pericarditis: diagnosis and management. Am J Cardiovasc Drugs 2005; 5(2): 103–112

    Article  PubMed  Google Scholar 

  97. Klacsmann PG, Bulkley BH, Hutchins GM. The changed spectrum of purulent pericarditis. Am J Med 1977; 63: 666–673

    Article  PubMed  CAS  Google Scholar 

  98. Mann-Segal DDM, Shanahan EA, Jones B, Ramasamy D. Purulent pericarditis: rediscovery of an old remedy. J Thorac Cardiovasc Surg 1996; 111: 487–488

    Article  PubMed  CAS  Google Scholar 

  99. Defouilloy C, Meyer G, Slama M, et al. Intrapericardial fibrinolysis: a useful treatment in the management of purulent pericarditis. Intensive Care Med 1997; 23(1): 117–118

    Article  PubMed  CAS  Google Scholar 

  100. Cui HB, Chen XY, Cui CC, et al. Prevention of pericardial constriction by transcatheter intrapericardial fibrinolysis with urokinase. Chin Med Sci J 2005; 20(1): 5–10

    PubMed  Google Scholar 

  101. Allaria A, Michelli D, Capelli H, Berri G, Gutierrez D. Transient cardiac constriction following purulent pericarditis. Eur J Pediatr 1992; 151(4): 250–251

    Article  PubMed  CAS  Google Scholar 

  102. Leoncini G, Iurilli L, Queirolo A, Catrambone G. Primary and secondary purulent pericarditis in otherwise healthy adults. Interact Cardiovasc Thorac Surg 2006; 5(5): 652–654

    Article  PubMed  Google Scholar 

  103. Sagrista-Sauleda J, Barrabes JA, Permanyer-Miralda G, et al. Purulent pericarditis: review of a 20-year experience in a general hospital. J Am Coll Cardiol 1993; 22: 1661–1665

    Article  PubMed  CAS  Google Scholar 

  104. Maisch B, Seferovic PM, Ristic AD, et al. Task Force on the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology. Guidelines on the diagnosis and management of pericardial diseases. Executive summary. Eur Heart J 2004; 25(7): 587–610

    Article  PubMed  Google Scholar 

  105. Kennedy C, McEvoy S. Purulent pericarditis. Ir J Med Sci. 2009; 178 (1): 97–99

    Article  PubMed  CAS  Google Scholar 

  106. Liem NT, Tuan T, Dung le A. Thoracoscopic pericardiectomy for purulent pericarditis: experience with 21 cases. J Laparoendosc Adv Surg Tech A 2006; 16(5): 518–521

    Article  PubMed  Google Scholar 

  107. Wright LT, Smith DH, Rothman M, Metzger WI, Quash ET. Use of streptokinase-dornase in certain surgical conditions. J Int Coll Surg 1951; 15: 286–299

    PubMed  CAS  Google Scholar 

  108. Pierret R, Lorriaux A, Ratel J, Graillot M, Mesmacque R. Purulent pericarditis treated with streptokinase. Echo Med Nord 1953; 24(7): 232–233

    PubMed  CAS  Google Scholar 

  109. Huang CH, Wu CC, Lee YT. Thrombolytic therapy complicated hyperacute cardiac tamponade in a patient with purulent pericarditis. Int J Cardiol 1996; 55(2): 209–210

    Article  PubMed  CAS  Google Scholar 

  110. Maynar J, Corral E, Manzano A, et al. Intrapericardial streptokinase fibrinolysis in the management of purulent pneumococcal pericarditis. Intensive Care Med 1997; 23(8): 925–926

    PubMed  CAS  Google Scholar 

  111. Mann-Segal DD. The use of fibrinolytics in purulent pericarditis. Intensive Care Med 1999; 25(3): 338–339

    Article  PubMed  CAS  Google Scholar 

  112. Juneja R, Kothari SS, Saxena A, Sharma R, Joshi A. Intrapericardial streptokinase in purulent pericarditis. Arch Dis Child 1999; 80: 275–277

    Article  PubMed  CAS  Google Scholar 

  113. Bridgman PG. Failure of intrapericardial streptokinase in purulent pericarditis. Intensive Care Med 2001; 27(5): 942

    Article  PubMed  CAS  Google Scholar 

  114. Cakir O, Gurkan F, Balci AE, Eren N, Dikici B. Purulent pericarditis in childhood: ten years of experience. J Pediatr Surg 2002; 37(10): 1404–1408

    Article  PubMed  Google Scholar 

  115. Ustunsoy H, Celkan MA, Sivrikoz MC, et al. Intrapericardial fibrinolytic therapy in purulent pericarditis. Eur J Cardiothorac Surg 2002; 22(3): 373–376

    Article  PubMed  Google Scholar 

  116. Schafer M, Lepori M, Delabays A, Ruchat P, Schaller MD, Broccard AF. Intrapericardial urokinase irrigation and systemic corticosteroids: an alternative to pericardectomy for persistent fibrino-purulent pericarditis. Cardiovasc Surg 2002; 10(5): 508–511

    Article  PubMed  CAS  Google Scholar 

  117. Kamimura M, Suzuki T, Kudo K. Intrapericardial infusion of urokinase for the treatment of purulent pericarditis. Intern Med 2002; 41(5): 412–413

    Article  PubMed  Google Scholar 

  118. Tomkowski WZ, Kuca P, Gralec R, et al. Management of purulent pericarditis. Monaldi Arch Chest Dis 2003; 59(4): 308–309

    PubMed  CAS  Google Scholar 

  119. Zimmermann C, Braun B, Hust MH. Intrapericardial fibrinolysis as a therapeutic option in a case of purulent pericarditis. Dtsch Med Wochenschr 2003; 128(43): 2248–2250

    Article  PubMed  CAS  Google Scholar 

  120. Tomkowski WZ, Gralec R, Kuca P, Burakowski J, Orłowski T, Kurzyna M. Effectiveness of intrapericardial administration of streptokinase in purulent pericarditis. Herz 2004; 29(8): 802–805

    Article  PubMed  Google Scholar 

  121. Ekim H, Demirbağ R. Intrapericardial streptokinase for purulent pericarditis. Surg Today 2004; 34: 569–572

    Article  PubMed  CAS  Google Scholar 

  122. Tillet WS, Sherry S, Read T. The use of Streptokinase- Streptodornase in the treatment of post pneumonic empyema. J Thorac Cardiovasc Surg 1951; 21: 275–297

    Google Scholar 

  123. Fraedrich G, Hofmann D, Efferhauser P, Jarder R. Instillation of fibrynolytic enzymes in the treatment of pleural empyema. Thorac Cardiovasc Surg 1982; 30: 36–38

    Article  PubMed  CAS  Google Scholar 

  124. Reznikoff CP, Fish JT, Coursin DB. Pericardial infusion of tissue plasminogen activator in fibropurulent pericarditis. J Intensive Care Med 2003; 18(1): 47–51

    Article  PubMed  Google Scholar 

  125. Bigham MT, Brady PW, Manning PB, Jacobs BR, Kimball TR, Wong HR. Therapeutic application of intrapericardial tissue plasminogen activator in a 4-month-old child with complex fibropurulent pericarditis. Pediatr Crit Care Med 2008; 9(1): e1–4

    Article  PubMed  Google Scholar 

  126. Aye RW, Froese DP, Hill LD. Use of purified streptokinase in empyema and hemothorax. Am J Surg 1991; 161: 560–562

    Article  PubMed  CAS  Google Scholar 

  127. Rubin RH, Moellering RC Jr. Clinical microbiologic and therapeutic aspects of purulent pericarditis. Am J Med 1975; 59: 68–78

    Article  PubMed  CAS  Google Scholar 

  128. Peuhkurinen K, Risteli L, Jounela A, Risteli J. Changes in interstitial collagen metabolism during acute myocardial infarction treated with streptokinase or tissue plasminogen activator. Am Heart J 1996; 131: 7–13

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer Medizin Verlag Heidelberg

About this chapter

Cite this chapter

Maisch, B., Ristić, A.D., Seferović, P.M., Tsang, T.S.M. (2011). Intrapericardial Treatment in Pericardial Disease. In: Interventional Pericardiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11335-2_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-11335-2_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-11334-5

  • Online ISBN: 978-3-642-11335-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics