Skip to main content

Part of the book series: Statistics for Social and Behavioral Sciences ((SSBS))

Abstract

This chapter reviews the first of the three phases of the multiphase optimization strategy (MOST), namely, preparation. In the preparation phase, the investigator develops a conceptual model of the behavioral, biobehavioral, or biomedical process of interest and how the intervention under development is to intervene on this process. As will be discussed, this conceptual model is even more detailed than a standard logic model . The conceptual model will guide every decision that is made throughout the subsequent phases of MOST. Based on the conceptual model, the investigator identifies a set of components that are candidates for inclusion in the optimized intervention and, if necessary, pilot tests the components. The investigator also specifies the criterion that will define the optimized intervention, that is, the optimization criterion . A clear and well-specified conceptual model, a set of candidate components that follow directly from this model, and an appropriate optimization criterion are all critical aspects of MOST. It is assumed that readers are familiar with the material in Chap. 1.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Ajzen, I. (1985). From intentions to actions: A theory of planned behavior. In J. Kuhl & J. Beckman (Eds.), Action control (pp. 11–39). Berlin, Germany: Springer Heidelberg.

    Chapter  Google Scholar 

  • Almirall, D., Nahum-Shani, I., Wang, L., & Kasari, C. (2018). Experimental designs for research on adaptive interventions: Singly and sequentially randomized trials. In L. M. Collins & K. C. Kugler (Eds.), Optimization of multicomponent behavioral, biobehavioral, and biomedical interventions: Advanced topics (forthcoming). New York, NY: Springer.

    Google Scholar 

  • Azar, M. M., Springer, S. A., Meyer, J. P., & Altice, F. L. (2010). A systematic review of the impact of alcohol use disorders on HIV treatment outcomes, adherence to antiretroviral therapy and health care utilization. Drug and Alcohol Dependence, 112(3), 178–193.

    Article  Google Scholar 

  • Bandura, A. (1986). Social foundations of thought and action. Englewood Cliffs, NJ: Prentice Hall.

    Google Scholar 

  • Bandura, A. (1977). Social learning theory. Englewood Cliffs, NJ: Prentice Hall.

    Google Scholar 

  • Boykoff, N., Moieni, M., & Subramanian, S. K. (2009). Confronting chemobrain: An in-depth look at survivors’ reports of impact on work, social networks, and health care response. Journal of Cancer Survivorship, 3(4), 223–232.

    Article  Google Scholar 

  • Braithwaite, R. S., & Bryant, K. J. (2010). Influence of alcohol consumption on adherence to and toxicity of antiretroviral therapy and survival. Alcohol Research & Health, 33(3), 280.

    Google Scholar 

  • Brown, J. L., Littlewood, R. A., & Vanable, P. A. (2013). Social-cognitive correlates of antiretroviral therapy adherence among HIV-infected individuals receiving infectious disease care in a medium-sized northeastern US city. AIDS Care, 25(9), 1149–1158.

    Article  Google Scholar 

  • Collins, L. M., & Kugler, K. C. (Eds.). (2018). Optimization of multicomponent behavioral, biobehavioral, and biomedical interventions: Advanced topics. New York, NY: Springer.

    Google Scholar 

  • Collins, L. M., Kugler, K. C., & Gwadz, M. V. (2016). Optimization of multicomponent behavioral and biobehavioral interventions for the prevention and treatment of HIV/AIDS. AIDS and Behavior, 20, 197–214.

    Article  Google Scholar 

  • Cruess, D. G., Kalichman, S. C., Amaral, C., Swetzes, C., Cherry, C., & Kalichman, M. O. (2012). Benefits of adherence to psychotropic medications on depressive symptoms and antiretroviral medication adherence among men and women living with HIV/AIDS. Annals of Behavioral Medicine, 43(2), 189–197.

    Article  Google Scholar 

  • Duncan, L. G., Moskowitz, J. T., Neilands, T. B., Dilworth, S. E., Hecht, F. M., & Johnson, M. O. (2012). Mindfulness-based stress reduction for HIV treatment side effects: A randomized, wait-list controlled trial. Journal of Pain and Symptom Management, 43(2), 161–171.

    Article  Google Scholar 

  • Dziak, J. (2018). Optimizing the cost-effectiveness of a multicomponent intervention using data from a factorial experiment: Considerations, open questions, and tradeoffs among multiple outcomes. In L. M. Collins & K. C. Kugler (Eds.), Optimization of multicomponent behavioral, biobehavioral, and biomedical interventions: Advanced topics (forthcoming). New York, NY: Springer.

    Google Scholar 

  • Glass, T. R., Battegay, M., Cavassini, M., De Geest, S., Furrer, H., Vernazza, P. L., … Swiss HIV Cohort Study. (2010). Longitudinal analysis of patterns and predictors of changes in self-reported adherence to antiretroviral therapy: Swiss HIV cohort study. Journal of Acquired Immune Deficiency Syndromes, 54(2), 197–203.

    Google Scholar 

  • Gonzalez, J. S., Batchelder, A. W., Psaros, C., & Safren, S. A. (2011). Depression and HIV/AIDS treatment nonadherence: A review and meta-analysis. Journal of Acquired Immune Deficiency Syndromes (1999), 58(2), 181–187.

    Article  Google Scholar 

  • Grant, R. M., Lama, J. R., Anderson, P. L., McMahan, V., Liu, A. Y., Vargas, L., … Glidden, D. V. (2010). Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. New England Journal of Medicine, 363(27), 2587–2599.

    Article  Google Scholar 

  • Harris, G. E., & Larsen, D. (2007). HIV peer counseling and the development of hope: Perspectives from peer counselors and peer counseling recipients. AIDS Patient Care and STDs, 21(11), 843–860.

    Article  Google Scholar 

  • Hendershot, C. S., Stoner, S. A., Pantalone, D. W., & Simoni, J. M. (2009). Alcohol use and antiretroviral adherence: Review and meta-analysis. Journal of Acquired Immune Deficiency Syndromes, 52(2), 180.

    Article  Google Scholar 

  • Klesges, L. M., Estabrooks, P. A., Dzewaltowski, D. A., Bull, S. S., & Glasgow, R. E. (2005). Beginning with the application in mind: Designing and planning health behavior change interventions to enhance dissemination. Annals of Behavioral Medicine, 29(2), 66–75.

    Article  Google Scholar 

  • Langebeek, N., Gisolf, E. H., Reiss, P., Vervoort, S. C., Thóra, B., Richter, C., … Nieuwkerk, P. T. (2014). Predictors and correlates of adherence to combination antiretroviral therapy (cART) for chronic HIV infection: A meta-analysis. BMC Medicine, 12(1), 142.

    Article  Google Scholar 

  • Leon, A. C., Davis, L. L., & Kraemer, H. C. (2011). The role and interpretation of pilot studies in clinical research. Journal of Psychiatric Research, 45(5), 626–629.

    Article  Google Scholar 

  • MacKinnon, D. P. (2008). Introduction to statistical mediation analysis. New York: Lawrence Erlbaum Associates.

    Google Scholar 

  • McIntosh, R. C., & Rosselli, M. (2012). Stress and coping in women living with HIV: A meta-analytic review. AIDS and Behavior, 16(8), 2144–2159.

    Article  Google Scholar 

  • Mo, P. K., & Coulson, N. S. (2008). Exploring the communication of social support within virtual communities: A content analysis of messages posted to an online HIV/AIDS support group. Cyberpsychology & Behavior, 11(3), 371–374.

    Article  Google Scholar 

  • Norton, W. E., Amico, K. R., Fisher, W. A., Shuper, P. A., Ferrer, R. A., Cornman, D. H., … Fisher, J. D. (2010). Information–motivation–behavioral skills barriers associated with intentional versus unintentional ARV non-adherence behavior among HIV+ patients in clinical care. AIDS Care, 22(8), 979–987.

    Article  Google Scholar 

  • Nyamathi, A., Flaskerud, J. H., Leake, B., Dixon, E. L., & Lu, A. (2001). Evaluating the impact of peer, nurse case-managed, and standard HIV risk-reduction programs on psychosocial and health-promoting behavioral outcomes among homeless women. Research in Nursing & Health, 24(5), 410–422.

    Article  Google Scholar 

  • Parsons, J. T., Golub, S. A., Rosof, E., & Holder, C. (2007). Motivational interviewing and cognitive-behavioral intervention to improve HIV medication adherence among hazardous drinkers: A randomized controlled trial. Journal of Acquired Immune Deficiency Syndrome, 46(4), 443.

    Article  Google Scholar 

  • Purcell, D. W., Latka, M. H., Metsch, L. R., Latkin, C. A., Gómez, C. A., Mizuno, Y., … INSPIRE Study Team. (2007). Results from a randomized controlled trial of a peer-mentoring intervention to reduce HIV transmission and increase access to care and adherence to HIV medications among HIV-seropositive injection drug users. Journal of Acquired Immune Deficiency Syndromes, 46, S35–S47.

    Article  Google Scholar 

  • Rivera, D. E., Hekler, E. B., Savage, J. S., & Downs, D. S. (2018). Intensively adaptive interventions using control systems engineering: Two illustrative examples. In L. M. Collins & K. C. Kugler (Eds.), Optimization of multicomponent behavioral, biobehavioral, and biomedical interventions: Advanced topics (forthcoming). New York, NY: Springer.

    Google Scholar 

  • Safren, S. A., Reisner, S. L., Herrick, A., Mimiaga, M. J., & Stall, R. (2010). Mental health and HIV risk in men who have sex with men. Journal of Acquired Immune Deficiency Syndromes (1999), 55(Suppl 2), S74.

    Article  Google Scholar 

  • Shuper, P. A., Neuman, M., Kanteres, F., Baliunas, D., Joharchi, N., & Rehm, J. (2010). Causal considerations on alcohol and HIV/AIDS—A systematic review. Alcohol and Alcoholism, 45(2), 159–166.

    Article  Google Scholar 

  • Springer, S. A., Dushaj, A., & Azar, M. M. (2012). The impact of DSM-IV mental disorders on adherence to combination antiretroviral therapy among adult persons living with HIV/AIDS: A systematic review. AIDS and Behavior, 16(8), 2119–2143.

    Article  Google Scholar 

  • Sullivan, L. E., Goulet, J. L., Justice, A. C., & Fiellin, D. A. (2011). Alcohol consumption and depressive symptoms over time: A longitudinal study of patients with and without HIV infection. Drug and Alcohol Dependence, 117(2), 158–163.

    Article  Google Scholar 

  • Uhrig, J. D., Lewis, M. A., Bann, C. M., Harris, J. L., Furberg, R. D., Coomes, C. M., & Kuhns, L. M. (2012). Addressing HIV knowledge, risk reduction, social support, and patient involvement using SMS: Results of a proof-of-concept study. Journal of Health Communication, 17(sup1), 128–145.

    Article  Google Scholar 

  • Van Ryzin, M. J., Roseth, C. J., Fosco, G. M., Lee, Y. K., & Chen, I. C. (2016). A component-centered meta-analysis of family-based prevention programs for adolescent substance use. Clinical Psychology Review, 45, 72–80.

    Article  Google Scholar 

  • W. K. Kellogg Foundation. (2004). Using logic models to bring together planning, evaluation, and action: Logic model development guide. Battle Creek, MI W.K. Kellogg Foundation. https://www.wkkf.org/resource-directory/resource/2006/02/wk-kellogg-foundation-logic-model-development-guide, downloaded 6/29/2017.

  • Wu, E. S., Metzger, D. S., Lynch, K. G., & Douglas, S. D. (2011). Association between alcohol use and HIV viral load. Journal of Acquired Immune Deficiency Syndromes (1999), 56(5), e129.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Collins, L.M. (2018). The Preparation Phase of MOST. In: Optimization of Behavioral, Biobehavioral, and Biomedical Interventions. Statistics for Social and Behavioral Sciences. Springer, Cham. https://doi.org/10.1007/978-3-319-72206-1_2

Download citation

Publish with us

Policies and ethics