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Asymmetric Diabetic Neuropathy: Radiculoplexus Neuropathies, Mononeuropathies, and Cranial Neuropathies

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Diabetic Neuropathy

Part of the book series: Contemporary Diabetes ((CDI))

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Abstract

Diabetic neuropathy is the most common acquired neuropathy in the world. It can be seen in up to 50% in diabetic patients [1]. The clinical manifestations of diabetic neuropathy vary, ranging from predominantly sensory symptoms sometimes with associated neuropathic pain in diabetic sensorimotor polyneuropathy to asymmetrical or multifocal weakness, pain, and sensory loss in diabetic radiculoplexus neuropathy. There are different ways of classifying diabetic neuropathy. One way is dividing diabetic neuropathy into two major categories: symmetric and asymmetric neuropathies [2] (Table 1). Asymmetric diabetic neuropathies consist of three major types: diabetic radiculoplexus neuropathies, diabetic mononeuropathies, and diabetic cranial neuropathies [2]. Even though asymmetric diabetic neuropathies are less common than symmetric diabetic neuropathies, they are still important to correctly diagnose as they have different underlying pathophysiology, may be misdiagnosed as the other forms of neuropathies with similar clinical manifestations and perhaps most importantly may respond to immunotherapy or other therapeutic interventions. This chapter describes the asymmetric diabetic neuropathies in details.

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Disclosure Statement

Pariwat Thaisetthawatkul MD has nothing to disclose.

P. James B. Dyck MD has nothing to disclose.

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Authors and Affiliations

  1. Department of Neurological Sciences, University of Nebraska Medical Center, 988435 Nebraska Medical Center, Omaha, NE, USA

    Pariwat Thaisetthawatkul

  2. Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN, USA

    P. James B. Dyck

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Editors and Affiliations

  1. Royal Hallamshire Hospital, Sheffield Teaching Hospitals and the University of Sheffield Director of Diabetes Research, Sheffield, UK

    Solomon Tesfaye

  2. Beth Israel Deaconess Medical Center, Boston, MA, USA

    Christopher H. Gibbons

  3. Weill Cornell Medicine, Cornell University, Doha, Qatar

    Rayaz Ahmed Malik

  4. Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA

    Aristidis Veves

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Thaisetthawatkul, P., Dyck, P.J.B. (2023). Asymmetric Diabetic Neuropathy: Radiculoplexus Neuropathies, Mononeuropathies, and Cranial Neuropathies. In: Tesfaye, S., Gibbons, C.H., Malik, R.A., Veves, A. (eds) Diabetic Neuropathy. Contemporary Diabetes. Humana, Cham. https://doi.org/10.1007/978-3-031-15613-7_10

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