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Cardiac Troponin for Risk Assessment and Management of Non-ST-Elevation Acute Coronary Syndrome

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Cardiovascular Biomarkers

Part of the book series: Contemporary Cardiology ((CONCARD))

Abstract

The clinical history, standard 12-lead electrocardiogram (ECG), and markers of myocardial necrosis constitute the basis for diagnosis and accurate risk assessment in patients with suspected of a non-ST-elevation acute coronary syndrome (NSTEACS). Cardiac troponin T and cardiac troponin I are ideal biochemical markers for the detection of myocardial necrosis in unstable patients who have repeated episodes of ischemia of varying intensity and several days’ duration, owing to their high sensitivity and specificity and their long duration of elevation. The troponins are independently predictive of mortality as well as of new or recurrent acute myocardial infarction after an episode of NSTEACS. By integrating the clinical history, ECG findings, and troponin results, it is possible to stratify the patients into low-, intermediate-, and high-risk groups. In addition, troponin results are useful for selecting patients who benefit from treatment with lowmolecular-weight heparin, glycoprotein IIb/IIIa antagonists, and invasive management.

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Author information

Authors and Affiliations

  1. Department of Cardiology and Uppsala Clinical Research Center, University Hospital, Uppsala, Sweden

    Bertil Lindahl MD, PhD, FESC (Associate Professor)

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  1. Bertil Lindahl MD, PhD, FESC
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Editors and Affiliations

  1. Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA

    David A. Morrow MD, MPH

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© 2006 Humana Press Inc., Totowa, NJ

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Lindahl, B. (2006). Cardiac Troponin for Risk Assessment and Management of Non-ST-Elevation Acute Coronary Syndrome. In: Morrow, D.A. (eds) Cardiovascular Biomarkers. Contemporary Cardiology. Humana Press. https://doi.org/10.1007/978-1-59745-051-5_5

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  • DOI: https://doi.org/10.1007/978-1-59745-051-5_5

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-526-2

  • Online ISBN: 978-1-59745-051-5

  • eBook Packages: MedicineMedicine (R0)

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