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Functional Magnetic Resonance Imaging in Developmental Psychopathology: The Brain as a Window into the Development and Treatment of Psychopathology

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Handbook of Developmental Psychopathology

Abstract

The development of psychopathology results from a complex interplay between genetic and environmental influences over time. The use of functional magnetic resonance imaging (fMRI) allows for the examination of brain function as a potential mediator of these interactions. Throughout the chapter, two applications of fMRI to understanding the development and treatment of psychopathology are discussed. First, fMRI can be used to examine the association between genetic or epigenetic variation and neural function as a means of elucidating the developmental pathways involved in gene x environment interactions on risk for psychopathology. Second, fMRI has applications for the development and testing of novel treatments for psychiatric disorders. Research reviewed focuses on anxiety disorders and autism spectrum disorder as examples to illustrate how the inclusion of fMRI as a level of analysis can advance understanding of the development and treatment of psychopathology.

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Swartz, J.R., Monk, C.S. (2014). Functional Magnetic Resonance Imaging in Developmental Psychopathology: The Brain as a Window into the Development and Treatment of Psychopathology. In: Lewis, M., Rudolph, K. (eds) Handbook of Developmental Psychopathology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-9608-3_14

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