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Effects of Sleep Deficiency on Hormones, Cytokines, and Metabolism

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Impact of Sleep and Sleep Disturbances on Obesity and Cancer

Part of the book series: Energy Balance and Cancer ((EBAC,volume 8))

Abstract

What are the best approaches to reduce the staggering health and economic costs of the diabetes and obesity epidemics? Traditional efforts have centered on diet and exercise, which are key health behaviors during wakefulness. Yet, mounting evidence supports the addition of sleep as a third pillar of health. Increasingly, scientific research suggests insufficient sleep puts Americans at risk for weight gain and impaired glucose regulation. Synthesizing epidemiological studies with clinical experiments enables a more complete understanding of these relationships by tying population-level trends to underlying mechanisms and causes. Although the associations between sleep, obesity, and diabetes and their intertwined mechanisms are still emerging, the current “epidemic” of insufficient sleep seems to warrant individual, behavioral, and policy interventions.

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Authors and Affiliations

  1. Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA

    Orfeu M. Buxton Ph.D.

  2. Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA

    Orfeu M. Buxton Ph.D.

  3. Department of Biobehavioral Health, Pennsylvania State University, University Park, PA, USA

    Orfeu M. Buxton Ph.D.

  4. Department of Social and Behavioral Sciences, Harvard School of Public Health, 219 Biobehavioral Health Building, Boston, MA, 16802, USA

    Orfeu M. Buxton Ph.D.

  5. Cedars-Sinai Medical Center, Diabetes and Obesity Research Institute, 8700 West Beverly Boulevard, THAE107, Los Angeles, CA, 90048, USA

    Josiane L. Broussard Ph.D.

  6. Harvard University, 9 Bow Street, Cambridge, MA, 02138, USA

    Alexa Katherine Zahl

  7. Departments of Psychiatry, Psychology, and Clinical and Translational Science, University of Pittsburgh School of Medicine, 3811 O’Hara Street, Suite E-1101, Pittsburgh, PA, USA

    Martica Hall M.H., Ph.D.

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  1. Orfeu M. Buxton Ph.D.
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  2. Josiane L. Broussard Ph.D.
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  3. Alexa Katherine Zahl
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  4. Martica Hall M.H., Ph.D.
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Correspondence to Orfeu M. Buxton Ph.D. .

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Editors and Affiliations

  1. Department of Medicine, Harvard Medical School Brigham and Women's Hospital, Boston, Massachusetts, USA

    Susan Redline

  2. Center for Science, Health & Society, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA

    Nathan A. Berger

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Buxton, O.M., Broussard, J.L., Zahl, A.K., Hall, M. (2014). Effects of Sleep Deficiency on Hormones, Cytokines, and Metabolism. In: Redline, S., Berger, N. (eds) Impact of Sleep and Sleep Disturbances on Obesity and Cancer. Energy Balance and Cancer, vol 8. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9527-7_2

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