Abstract
For many decades of the twentieth century, gender dysphoria was seen as an intrinsic symptom of another psychiatric disorder (e.g., schizophrenia) that should be resolved by addressing the “underlying” psychiatric disorder. DSM-III (American Psychiatric Association, 1980) broke with that view and classified the gender identity disorders as a separate category of psychopathology. In contrast, many argue today that gender nonconformity and even gender dysphoria are not (psycho)pathology per se and that sex reassignment therapies are the most effective therapies for gender dysphoria (e.g., World Professional Association for Transgender Health, 2011).
However, based on the prevalence rate of comorbidity, many are convinced that the diagnosis and treatment of psychiatric comorbidity is of paramount importance for a proper diagnosis and for a successful treatment of gender dysphoria.
This chapter reviews the prevalence rate of comorbid Axis I and II disorders in persons with gender dysphoria (GD), explores theoretical models to explain comorbidity, and describes clinical implications. The central message is that we should avoid two pitfalls: First, we should avoid the assumption that all patients with GD must have comorbid disorders, and second, we should not assume that patients with GD will not have comorbid disorders. However, to ensure the best possible outcome of sex reassignment therapy and to prevent regret, comorbidity should be diagnosed and treated properly.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
á Campo, J., Nijman, H., Merckelbach, H., & Evers, C. (2003). Psychiatric comorbidity of gender identity disorders: A survey among Dutch psychiatrists. The American Journal of Psychiatry, 160, 1332–1336.
Algars, M., Alanko, K., Santttila, P., & Sandnabba, N. (2012). Disordered eating and gender identity disorder: A qualitative study. Eating Disorders, 20, 300–311.
American Psychiatric Association. (1980). Diagnostic and statistical manual of mental disorders (3rd ed.). Washington, DC: American Psychiatric Association.
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed. - Text Revision). Washington, DC: American Psychiatric Association.
Andrade, A., Kumaraiah, V., Mishra, H., Chatterji, S., & Andrade, C. (1995). Behaviour therapy for transsexualism. Indian Journal of Psychiatry, 37(3), 148–150.
Baltieri, D., & De Andrade, A. (2009). Schizophrenia modifying the expression of gender identity disorder. The Journal of Sexual Medicine, 6, 1185–1188.
Barlow, D., & Abel, G. (1976). Sexual deviation. In W. Craighead, A. Kazdin, & M. Mahoney (Eds.), Behavior modification: Principles, issues, and applications (pp. 341–360). Boston: Houghton Mifflin.
Barlow, D., Abel, G., & Blanchard, E. (1979). Gender identity change in transsexuals. Follow-up and replications. Archives of General Psychiatry, 36, 1001–1007.
Barlow, D., Reynolds, E., & Agras, W. (1973). Gender identity change in a transsexual. Archives of General Psychiatry, 28, 569–576.
Bockting, W. (2008). Psychotherapy and the real-life experience: from gender dichotomy to gender diversity. Sexologies, 17, 211–224.
Bockting, W., Coleman, E., & Benner, A., (2007). Stigma, mental health, and resilience among the U.S. Transgender population. 1st World Congress for sexual health. Cited in Bockting (2008).
Borras, L., Huguelet, P., & Eytan, A. (2007). Delusional ´´pseudotranssexualism´´ in schizophrenia. Psychiatry, 70, 175–179.
Brownell, K., & Barlow, D. (1980). The behavioral treatment of sexual deviation. In A. Goldstein & E. Foa (Eds.), Handbook of behavioral interventions: A clinical guide (pp. 604–672). New York: Wiley.
Byne, W., Bradley, S., Coleman, E., Eyler, A., Green, R., Menvielle, E., et al. (2012). Report of the American Psychiatric Association Task Force on Treatment of Gender Identity Disorder. Archives of Sexual Behaviour, 41, 759–896.
Chiland, C. (2003). Transsexualism; Illusions and reality. London: Continuum.
Cochran, S., & Mays, V. (2006). Estimating prevalence of mental and substance-suing disorders among lesbians and gay men from existing national health data. In A. Omoto & H. Kurtzman (Eds.), Sexual orientation and mental health (pp. 143–1650). Washington: American Psychological Association.
Cole, C., O’Boyle, M., Emory, L., & Meyer, W. (1997). Comorbidity of gender dysphoria and other major psychiatric diagnoses. Archives of Sexual Behavior, 26, 13–26.
Cramer, A., Waldorp, L., Han, L., Van der Maas, J., & Borsboom, D. (2010). Comorbidity: A network perspective. Behavioural and Brain Sciences, 33, 137–150.
De Cuypere, G. (1993). Schizophrenia and symptomatic transsexualism: Two case reports. European Psychiatry, 8, 163–167.
De Vries, A., Noens, I., Cohen-Kettenis, P., van Berckelaer-Onnes, I., & Doreleijers, T. (2010). Autism spectrum disorders in gender dysphoric children and adolescents. Journal of Autism and Developmental Disorders, 40, 930–936.
Dhejne, C., Lichtenstein, P., Boman, M., Johansson, A., Langstrom, N., & Landen, M. (2011). Long-term follow-up of transsexual persons undergoing sex reassignment surgery: Cohort study Sweden. PLoS One, 22, e16885. doi:10.1371.
Gijs, L., & Brewaeys, A. (2007). Surgical treatment of gender identity dysphoria in adults and adolescents: Recent developments, effectiveness, and change. Annual Review of Sex Research, 18, 178–224.
Gómez-Gil, E., Vidal-Hagemeijer, A., & Salamero, M. (2008). MMPI-2 characteristics of transsexuals requesting sex reassignment: Comparison of patients in prehormonal and presurgical phases. Journal of Personality Assessment, 90, 368–374.
Haas, A., Eliason, M., Mays, V., Mathy, R., Cochran, S., D’Augelli, A., et al. (2011). Suicide and suicide risk in lesbian, gay, bisexual, and transgender populations: Review and recommendations. Journal of Homosexuality, 58, 10–51.
Haraldsen, I., & Dahl, A. (2000). Symptom profiles of gender dysphoric patients of transsexual type compared to patients with personality disorder and healthy adults. Acta Psychiatrica Scandinavia, 102, 276–281.
Hepp, U., Kraemer, B., Schnyder, U., Miller, N., & Delsignore, A. (2005). Psychiatric comorbidity in gender identity disorder. Journal of Psychosomatic Research, 58, 259–261.
Hepp, U., & Milos, G. (2002). Gender identity disorder and eating disorders. International Journal of Eating Disorders, 32, 473–478.
Heylens, G., Elaut, E., Kreukels, B., Paap, M., Cerwenka, S., Richter-Appelt, H., et al. (2013). Psychiatric characteristics in transsexual individuals: A multi-centre study in four European countries. The British Journal of Psychiatry 202. DOI: 10.1192/bjp.bp.112.121954.
Hines, M. (2011). Gender development and the human brain. Annual Review of Neuroscience, 34, 69–88.
Hoenig, J., & Kenna, J. (1974). The prevalence of transsexualism in England and Wales. Britisch Journal of Psychiatry, 124, 181–190.
Hyman, S. (2010). The diagnosis of mental disorders: The problem of reification. Annual Review of Clinical Psychology, 6, 155–179.
Jones, R., Wheelwright, S., Farrell, K., Martin, E., Green, R., Di Ceglie, D., et al. (2012). Brief report: Female-to-male transsexual people and autistic traits. Journal of Autism and Developmental Disorders, 42, 301–306.
Kuhn, A., Bodmer, C., Stadlmayer, W., Kuhn, P., Mueller, M., & Birkhauser, M. (2009). Quality of life 15 years after sex reassignment surgery for transsexualism. Fertility and Sterility, 92, 1685–1689.
Lawrence, A. (2003). Factors associated with satisfaction or regret following male-to-female sex reassignment surgery. Archives of Sexual Behavior, 32, 229–315.
Lawrence, A. (2007). Transgender health concerns. In I. Meyer & M. Northbridge (Eds.), The health of sexual minorities. Public health perspectives on lesbian, gay, bisexual and transgender populations (pp. 473–505). New York, NY: Springer.
Lawrence, A., & Zucker, K. (2012). Gender identity disorders. In M. Hersen & D. Beidel (Eds.), Adult psychopathology and diagnosis (6th ed., pp. 601–635). London: Wiley.
Lehavot, K., & Simoni, J. (2011). The impact of minority stress on mental health and substance abuse among sexual minority women. Journal of Consulting and Clinical Psychology, 79, 159–170.
Lev, A. (2004). Transgender emergence. Therapeutic guidelines for working with gender-variant people and their families. London: Routledge.
Levine, S., & Solomon, A. (2010). Meanings and political implications of “Psychopathology” in a gender identity clinic: A report of 10 cases. Journal of Sex & Marital Therapy, 35, 40–57.
Links, P., Ansari, J., Fazalullasha, F., & Shah, R. (2012). The relationship of personality disorders and Axis I clinical disorders. In T. Widiger (Ed.), The Oxford handbook of personality disorders (pp. 237–259). Oxford: Oxford University Press.
Madeddu, F., Prunas, A., & Hartmann, D. (2009). Prevalence of Axis II disorders in a sample of clients undertaking psychiatric evaluation for sex reassignment surgery. Psychiatric Quarterly, 80, 261–267.
Marks, I., Green, R., & Mataix-Cole, D. (2000). Adult gender identity disorder can remit. Comprehensive Psychiatry, 41, 273–275.
Marks, I., & Mataix-Cole, D. (1997). Four-year remission of transsexualism after comorbid obsessive-compulsive disorder improved with self-exposure therapy. The British Journal of Psychiatry, 171, 389–390.
McLaughlin, K., Hatzenbuehler, M., Xuan, Z., & Conron, K. (2012). Disproportionate exposure to early-life adversity and sexual orientation disparities in psychiatric co-morbidity. Child Abuse & Neglect, 36, 645–655.
Meijer, I. (2007). Prejudice and discrimination as social stressors. In I. Meyer & M. Northhridge (Eds.), The health of sexual minorities: Public health perspectives on lesbian, gay, bisexual and transgender populations (pp. 222–267). New York: Springer.
Meyerowitz, J. (2002). How sex changed. A history of transsexuality in the United States. Cambridge: Harvard University Press.
Mizock, L., & Fleming, M. (2011). Transgender and gender variant populations with mental illness: Implications for clinical care. Professional Psychology: Research and Practice, 42, 208–213.
Murad, M., Elamin, M., Garcia, M., Mullan, R., Murad, A., Erwin, P., et al. (2010). Hormonal therapy and sex reassignment: A systematic review and meta-analysis of quality of life and psychosocial outcomes. Clinical Endocrinology, 72, 214–231.
Neeleman, A. (2007). The relevance of sexuality in the treatment of borderline personality disorder. Tijdschrift voor Psychiatrie, 49, 233–240.
Newcomb, M., & Mustanski, B. (2010). Internalized homophobia and internalizing mental health problems: A meta-analytic review. Clinical Psychology Review, 8, 1019–1029.
Nuttbrock, L., Hwanhng, S., Bockting, W., Rosenblum, A., Mason, M., Macri, M., et al. (2009). Psychiatric impact of gender-related abuse across the life course of male-to-female transgender persons. Journal of Sex Research, 46, 1–12.
Parks, G., & Hall, I. (2006). Gender dysphoria and cross-dressing in people with intellectual disability: A literature review. Mental Retardation, 44, 260–271.
Pfäfflin, F. (1992). Regrets after sex reassignment surgery. Journal of Psychology and Human Sexuality, 5, 69–85.
Selvaggi, G., & Bellringer, J. (2011). Gender reassignment surgery: An overview. Nature Reviews Urology, 8, 274–282.
Singh, A. (in press). Transgender youth of color and resilience: Negotiating oppression and finding support. Sex Roles.
Singh, D., McMain, S., & Zucker, K. (2011). Gender identity and sexual orientation in woman with borderline personality disorder. The Journal of Sexual Medicine, 8, 447–454.
Slatman, J., & Widdershoven, G. (2009). Being whole after amputation. The American Journal of Bioethics, 9, 48–49.
Smith, Y., van Goozen, S., Kuiper, A., & Cohen-Kettenis, P. (2005a). Sex reassignment: Outcomes and predictors of treatment for adolescent and adult transsexuals. Psychological Medicine, 35, 89–99.
Smith, Y., van Goozen, S., Kuiper, A., & Cohen-Kettenis, P. (2005b). transsexual subtypes: Clinical and theoretical significance. Psychiatry Research, 137, 151–160.
Socarides, C. (1969). The desire for sexual transformation: A psychiatric evaluation of transsexualism. The American Journal of Psychiatry, 125, 1419–1425.
Socarides, C. (1970). A psychoanalytic study of the desire for sexual transformation (´transsexualism´): The plaster-of-paris man. International Journal of Psychoanalyses, 51, 341–349.
Socarides, C. (1988). The preoedipal origin and psychoanalytic therapy of sexual perversions. Madison: International Universities Press.
South, S., Reichborn-Kjennerud, T., Eaton, N., & Krueger, R. (2012). Behavior and molecular genetics of personality disorders. In T. Widiger (Ed.), The Oxford handbook of personality disorders (pp. 143–165). Oxford: Oxford University Press.
Stoller, R. (1996). The gender disorders. In I. Rosen (Ed.), Sexual deviation (3rd ed., pp. 111–133). Oxford: Oxford University Press.
Terada, S., Matsumoto, Y., Sato, T., Okabe, N., Kishimoto, Y., & Uchitomi, Y. (2012). Suicidal ideation among patients with gender identity disorder. Psychiatry Research, 200, 469–474.
Torgersen, S. (2012). Epidemiology. In T. Widiger (Ed.), The Oxford handbook of personality disorders (pp. 186–205). Oxford: Oxford University Press.
Trull, T., Scheiderer, E., & Tomok, R. (2012). Axis II Comorbidity. In T. Widiger (Ed.), The Oxford handbook of personality disorders (pp. 219–236). Oxford: Oxford University Press.
Volkan, V., & Greer, W. (1996). True transsexualism. In I. Rosen (Ed.), Sexual deviation (3rd ed., pp. 158–173). Oxford: Oxford University Press.
Wallien, M. (2008). Gender dysphoria in children: Causes and consequences. Unpublished Academic dissertation
World Professional Association for Transgender Health. (2011). Standards of care for the health of transsexual, transgender and gender non-conforming people, 7th Version. http://www.wpath.org/. Accessed January 2013.
Zucker, K., & Bradley, S. (1995). Gender identity disorders and psychosexual problems in children and adolescents. New York: Guilford Press.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer Science+Business Media New York
About this chapter
Cite this chapter
Gijs, L., van der Putten-Bierman, E., De Cuypere, G. (2014). Psychiatric Comorbidity in Adults with Gender Identity Problems. In: Kreukels, B., Steensma, T., de Vries, A. (eds) Gender Dysphoria and Disorders of Sex Development. Focus on Sexuality Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-7441-8_13
Download citation
DOI: https://doi.org/10.1007/978-1-4614-7441-8_13
Published:
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4614-7440-1
Online ISBN: 978-1-4614-7441-8
eBook Packages: Behavioral ScienceBehavioral Science and Psychology (R0)