Skip to main content

Differential Diagnosis of Depression and Mood Disorders

  • Chapter
  • First Online:
Anxiety and Depression in Children and Adolescents
  • 10k Accesses

Abstract

Unlike anxiety that has normal developmental markers and characteristics, depression and mood disorders do not have age-related and predictable courses. Virtually everyone has experiences of being sad or having brief periods of depression associated with a significant distressing event (e.g., loss of a loved one, situational stress), but they do not cause significant or chronic impairment and do not follow a typical developmental course. Although adolescents are often characterized as “moody” or irritable or experience “hassles,” their behaviors typically do not meet diagnostic criteria for a depression or a mood disorder and they do not significantly interfere with overall functioning. Like anxiety, however, depression is an internalizing problem that can have negative effects on various spheres of psychological and social functioning. A focus on depression in children and youth is relatively recent, having received increased clinical and research emphasis in the last two to three decades.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 129.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Achenbach, T. (1991). Manual for the child behavior checklist and 1991 child behavior profile. Burlington, VT: University of Vermont, Department of Psychiatry.

    Google Scholar 

  • American Psychiatric Association. (1952). Diagnostic and statistical manual of mental disorders (DSM-I). Washington, DC: Author.

    Google Scholar 

  • American Psychiatric Association. (1968). Diagnostic and statistical manual of mental disorders-second edition (DSM-II). Washington, DC: American Psychiatric Association.

    Google Scholar 

  • American Psychiatric Association. (1980). Diagnostic and statistical manual of mental disorders-third edition (DSM-III). Washington, DC: American Psychiatric Association.

    Google Scholar 

  • American Psychiatric Association. (1987). Diagnostic and statistical manual of mental disorders-third edition revised (DSM-III-R). Washington, DC: American Psychiatric Association.

    Google Scholar 

  • American Psychological Association. (1994). Diagnostic and statistical manual of mental disorder-fourth edition (DSM-IV). Washington, DC: Author.

    Google Scholar 

  • American Psychological Association. (2000). Diagnostic and statistical manual of mental disorder-fourth edition-text revision (DSM-IV-TR). Washington, DC: American Psychological Association.

    Book  Google Scholar 

  • Angold, A., Costello, E. J., & Erkanli, A. (1999a). Comorbidity. Journal of Child Psychology and Psychiatry and Allied Disciplines, 40, 57–87.

    Article  Google Scholar 

  • Angold, A., Costello, E. J., Erkanli, A., & Worthman, C. M. (1999b). Pubertal changes in hormones of adolescent girls. Psychological Medicine, 29, 1043–1053.

    Article  PubMed  Google Scholar 

  • Angold, A., Costello, E. J., & Worthman, C. M. (1998). Puberty and depression: The roles of age, pubertal status, and pubertal timing. Psychological Medicine, 28, 51–61.

    Article  PubMed  Google Scholar 

  • Avenevoli, S., Stolar, J., Li, J., Dierker, L., & Merikangas, K. R. (2001). Comorbidity of depression in children and adolescents: Models and evidence from a prospective high-risk family study. Biological Psychiatry, 49, 1071–1081.

    Article  PubMed  Google Scholar 

  • Beck, A. T. (1967). Depression: Clinical, experimental, and theoretical aspects. New York: Hoeber.

    Google Scholar 

  • Biederman, J. (1998). Resolved: Mania is mistaken for ADHD in prepubertal children. Journal of the American Academy of Child and Adolescent Psychiatry, 37, 1091–1093.

    Article  PubMed  Google Scholar 

  • Biederman, J., Faraone, S. V., Mick, E., Wozniak, J., Chen, L., Ouelette, C., et al. (1996). Attention-deficit hyperactivity disorder and juvenile mania: An overlooked comorbidity? Journal of the American Academy of Child and Adolescent Psychiatry, 35, 997–1008.

    Article  PubMed  Google Scholar 

  • Birmaher, B., Ryan, N. D., Williamson, D. E., Brent, D. A., Kaufman, J., Dahl, R. E., Perel, J., & Nelson, B. (1996). Childhood and adolescent depression: A review of the past 10 years. Part I. Journal of the American Academy of Child and Adolescent Psychiatry, 35, 1427–1439.

    Article  PubMed  Google Scholar 

  • Cooper, P. J., & Goodyear, I. (1993). A community study of depression in adolescent girls: I. Estimates of symptom and syndrome prevalence. British Journal of Psychiatry, 163, 369–374.

    Article  PubMed  Google Scholar 

  • Costello, E. J., Angold, A., Burns, B. J., Stangl, D. K., Tweed, D. L., Erkanli, A., & Wortham, C. M. (1996). The Great Smoky Mountain Study of Youth: Goals, design, methods, and the prevalence of DSM-III-R disorders. Archives of General Psychiatry, 53, 1129–1136.

    Article  PubMed  Google Scholar 

  • Costello, E. J., Costello, A. J., Edelbrock, C., Burns, B. J., Dulcan, M. K., Brent, D. A., et al. (1988). Psychiatric disorders in pediatric primary care: Prevalence and risk factors. Archives of General Psychiatry, 45, 1107–1116.

    Article  PubMed  Google Scholar 

  • Costello, E. J., Egger, H. L., & Angold, A. (2004). The developmental epidemiology of anxiety disorders. In T. H. Ollendick & J. S. March (Eds.), Phobic and anxiety disorders in children and adolescents: A clinician’s guide to effective psychosocial and pharmacological interventions (pp. 61–91). New York: Oxford University Press.

    Google Scholar 

  • Costello, E. J., Mustillo, S., Erkanli, A., Keeler, G., & Angold, A. (2003). Prevalence and development of psychiatric disorders in childhood and adolescence. Archives of General Psychiatry, 60, 837–844.

    Article  PubMed  Google Scholar 

  • Faedda, G., Baldessarini, R., Suppes, T., Tondo, L., Becker, I., & Lipschitz, D. (1995). Pediatric-onset bipolar disorder: A neglected clinical and public health problem. Harvard Review of Psychiatry, 3, 171–195.

    Article  PubMed  Google Scholar 

  • Fleming, J. E., Offord, D. R., & Boyle, M. H. (1989). Prevalence of childhood and adolescent depression in the community—Ontario Child Health Study. British Journal of Psychiatry, 155, 647–654.

    PubMed  Google Scholar 

  • Garrison, C. A., Jackson, K. L., Marsteller, F., McKeown, R., & Addy, C. (1990). A longitudinal study of depressive symptomatology in young adolescents. Journal of the American Academy of Child and Adolescent Psychiatry, 29, 581–585.

    Article  PubMed  Google Scholar 

  • Gibb, B. E., Wheeler, R., Alloy, L. B., & Abramson, L. Y. (2001). Emotional, physical, and sexual maltreatment in childhood versus adolescence and personality dysfunction in young adulthood. Journal of Personality Disorders, 15, 505–511.

    Article  PubMed  Google Scholar 

  • Goodman, S. H., Schwab-Stone, M., Lahey, B. B., Shaffer, D., & Jensen, P. S. (2000). Major depression and dysthymia in children and adolescents: Discriminant validity and differential consequences in a community sample. Journal of the American Academy of Child and Adolescent Psychiatry, 39, 761–770.

    Article  PubMed  Google Scholar 

  • Hankin, B. L., Abramson, L. Y., Moffitt, T. E., Silva, P. A., McGee, R., & Angell, K. E. (1998). Development of depression from preadolescence to young adulthood: Emerging gender differences in a 10-year longitudinal study. Journal of Abnormal Psychology, 107, 128–140.

    Article  PubMed  Google Scholar 

  • Horowitz, A. V., Widom, C. S., Mclaughlin, J., & White, H. R. (2001). The impact of childhood abuse and neglect on adult mental health: A prospective study. Journal of Health and Social Behavior, 42, 184–201.

    Article  Google Scholar 

  • Kashani, J. H., & Carlson, G. A. (1987). Seriously depressed preschoolers. American Journal of Psychiatry, 144, 348–350.

    PubMed  Google Scholar 

  • Kashani, J. H., McGee, R. O., Clarkson, S. E., Anderson, J. C., Walton, L. A., Williams, S., et al. (1983). Depression in a sample of 9-year-old children. Archives of General Psychiatry, 40, 1217–1223.

    Article  PubMed  Google Scholar 

  • Kaslow, N. J., & Rehm, L. P. (1991). Childhood depression. In T. J. Kratochwill & R. J. Morris (Eds.), The practice of child therapy (2nd ed., pp. 43–75). New York: Pergamon.

    Google Scholar 

  • Kaufman, J. (1991). Depressive disorders in maltreated children. Journal of the American Academy of Child and Adolescent Psychiatry, 30, 257–265.

    Article  PubMed  Google Scholar 

  • Kessler, R. C., Anenevoli, S., & Merikangas, K. R. (2001). Mood disorders in children and adolescents: An epidemiologic perspective. Biological Psychiatry, 49, 1002–1014.

    Article  PubMed  Google Scholar 

  • Kessler, R., Berglund, P., Demler, O., Jin, R., & Walters, E. (2005). Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry, 62, 593–602.

    Article  PubMed  Google Scholar 

  • Kessler, R. C., McGonagle, K., Swartz, M., Blazer, D., & Nelson, C. (1993). Sex and depression in the National Comorbidity Survey: I. Lifetime prevalence, chronicity, and recurrence. Journal of Affective Disorders, 29, 85–96.

    Article  PubMed  Google Scholar 

  • Kessler, R. C., & Walters, E. E. (1998). Epidemiology of DSM-III-R major depression and minor depression among adolescents and young adults in the National Comorbidity Survey. Depression and Anxiety, 7, 3–14.

    Article  PubMed  Google Scholar 

  • Kim, J., & Cichetti, D. (2004). A process model of mother-child problems in maltreated and nonmaltreated children. Journal of Abnormal Child Psychology, 32, 341–354.

    Article  PubMed  Google Scholar 

  • Kim-Cohen, J., Caspi, A., Moffit, T. E., Harington, H. L., Milne, B. J., & Poulton, R. (2003). Prior juvenile diagnoses in adults with mental disorder: Developmental follow-back of a prospective-longitudinal cohort. Archives of General Psychiatry, 60, 709–717.

    Article  PubMed  Google Scholar 

  • Kovacs, M. (1990). Comorbid anxiety disorders in childhood-onset depression. In J. D. Maser & C. R. Cloninger (Eds.), Comorbidity of mood and anxiety disorders (pp. 272–281). Washington, DC: American Psychiatric Press.

    Google Scholar 

  • Kovacs, M., Gastonis, C., Paulauskas, L. L., & Richards, C. (1989). Depressive disorders in childhood: IV. A longitudinal study of comorbidity with and without risk for anxiety disorders. Archives of General Psychiatry, 46, 776–782.

    Article  PubMed  Google Scholar 

  • Lefkowitz, M. M., & Burton, N. (1978). Childhood depression: A critique of the concept. Psychological Bulletin, 85, 716–726.

    Article  PubMed  Google Scholar 

  • Lewinshohn, P. M., Hops, H., Roberts, R. E., Seely, J. R., & Andrews, J. A. (1993). Adolescent psychopathology: I. Prevalence and incidence of depression and other DSM-III-R disorders in high school students. Journal of Abnormal Psychology, 102, 133–144.

    Article  Google Scholar 

  • McGee, R., Feehan, M., Williams, S., & Anderson, J. (1992). DSM-III disorders from age 11 to age 15 years. Journal of the American Academy of Child and Adolescent Psychiatry, 29, 611–619.

    Article  Google Scholar 

  • Newman, D. L., Moffit, T. E., Caspi, A., & Magdol, L. (1996). Psychiatric disorder in a birth cohort of young adults: Prevalence, comorbidity, clinical significance, and new case incidence from ages 11-21. Journal of Consulting and Clinical Psychology, 64, 552–562.

    Article  PubMed  Google Scholar 

  • Nolen-Hoeksema, S. (2000). The role of rumination in depressive disorders and mixed anxiety/depressive symptoms. Journal of Abnormal Psychology, 109, 504–511.

    Article  PubMed  Google Scholar 

  • Offord, D. R., Boyle, M. H., Racine, Y. A., Fleming, J. E., Cadman, D. T., Blum, H. M., Bryne, C., Links, P. S., Lipman, E. L., MacMillan, H. L., Grant, N. I. R., Sanford, M. N., Szatmari, P., Thomas, H., & Woodward, C. A. (1992). Outcome, prognosis, and risk in a longitudinal follow-up study. Journal of the American Academy of Child and Adolescent Psychiatry, 31, 916–923.

    Article  PubMed  Google Scholar 

  • Rudolph, K. D. (2002). Gender differences in emotional responses to interpersonal stress during adolescence. Journal of Adolescent Health, 30, 3–13.

    Article  PubMed  Google Scholar 

  • Rudolph, K. D., & Hammen, C. (1999). Age and gender as determinants of stress exposure, generation, and reactions in youngsters; A transactional perspective. Child Development, 70, 660–677.

    Article  PubMed  Google Scholar 

  • Tillman, R., & Geller, B. (2003). Definitions of rapid, ultra-rapid, and ultradian cycling and of episode duration in pediatric and adult bipolar disorders: A proposal to distinguish episodes from cycles. Journal of Child and Adolescent Psychopharmacology, 13, 267–271.

    Article  PubMed  Google Scholar 

  • Toth, S. L., & Cichetti, D. (1996). Patterns of relatedness and depressive symptomatology in maltreated children. Journal of Consulting and Clinical Psychology, 64, 32–41.

    Article  PubMed  Google Scholar 

  • Toth, S. L., Manly, J. T., & Cichetti, D. (1992). Child maltreatment and vulnerability to depression. Development and Psychopathology, 4, 97–112.

    Article  Google Scholar 

  • Toth, S. L., Maughan, A., Manly, J. T., Spagnola, M., & Cichetti, D. (2002). The relative efficacy of two interventions in altering maltreated children’s representational models: Implications for attachment theory. Development and Psychopathology, 14, 777–808.

    Article  Google Scholar 

  • Weissman, M. M., Wolk, S., Goldstein, R. B., Moreau, D., Adams, P., Greenwald, S., Klier, C. M., Ryan, N. D., Dahl, R. E., & Wickramaratne, P. (1999). Depressed adolescents grown up. Journal of the American Medical Association, 281, 1707–1713.

    Article  PubMed  Google Scholar 

  • Whitaker, A., Johnson, J., Shaffer, D., Rapoport, J. L., Kalikow, K., Walsh, B. T., et al. (1990). Uncommon troubles in young people: Prevalence estimates of selected psychiatric disorders in a nonreferred adolescent population. Archives of General Psychiatry, 47, 487–496.

    Article  PubMed  Google Scholar 

  • Youngstrom, E. A. (2009). Definitional issues in bipolar disorder over the life cycle. Clinical Psychology: Science and Practice, 16, 140–160.

    Article  Google Scholar 

  • Youngstrom, E. A. (2010). Bipolar disorder in children and adolescents. Workshop presented at the Annual Convention of the National Association of School Psychologists, Chicago, IL

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Huberty, T.J. (2012). Differential Diagnosis of Depression and Mood Disorders. In: Anxiety and Depression in Children and Adolescents. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3110-7_6

Download citation

Publish with us

Policies and ethics