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Injectables for the Treatment of Female Stress Urinary Incontinence

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Female Pelvic Reconstructive Surgery

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Abstract

Since the first report of injection of sodium morrhuate around the urethra by Murless in 1938,1 various materials have been injected into and around the urethra for urinary incontinence, as an alternative to surgery. Quackels2 reported paraffin wax in 1955 and Sachse3 used sclerosing agents in 1963. The initial results were poor, and significant complications such as pulmonary emboli and urethral sloughing were seen. Polytetrafluoroethylene (Teflon) paste was first introduced by Berg4 and then popularized by Politano5 in the 1970s. Shortliffe et al.6 published the first report on glutaraldehyde cross-linked collagen, and more recently autologous fat injection7 has been described. Newer agents, such as silicone microparticles8 and injectable micro-balloons, have also been reported.9

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Authors
  1. Sender Herschorn
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Editors and Affiliations

  1. Department of Obstetrics and Gynaecology, St. George’s Hospital Medical School, London, UK

    Stuart L. Stanton FRCS, FRCOG, FRANZCOG (Hon)

  2. Department of Urology, Southwestern Medical Center at Dallas, Dallas, Texas, USA

    Philippe E. Zimmern MD, FACS

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Herschorn, S. (2003). Injectables for the Treatment of Female Stress Urinary Incontinence. In: Stanton, S.L., Zimmern, P.E. (eds) Female Pelvic Reconstructive Surgery. Springer, London. https://doi.org/10.1007/978-1-4471-0659-3_5

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  • DOI: https://doi.org/10.1007/978-1-4471-0659-3_5

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-85233-362-1

  • Online ISBN: 978-1-4471-0659-3

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