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Magnetic Resonance Spectroscopy in Epilepsy

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MR Spectroscopy of Pediatric Brain Disorders

Abstract

Magnetic Resonance Spectroscopy (MRS) enables us to assess the metabolic changes in the brain of patients with epilepsy. Therefore it can provide complementary information to structural imaging. Structural MRI plays an important role in identifying the underlying epileptogenic substrate responsible for epilepsy. MRS identifies metabolic changes in the epileptogenic brain, which could be used to lateralize seizure focus, detect bilateral brain abnormalities such as bilateral temporal lobe epilepsy, identify the metabolic abnormalities in the epileptic brain, assess metabolic abnormalities in the epileptogenic zone that appears normal on structural MRI, predict surgical outcome, and improve our understanding of the pathophysiology of epileptogenic substrate.

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Authors and Affiliations

  1. Department of Diagnostic Imaging, Children’s Hospital of Eastern Ontario, Ottawa, ON, Canada

    Elka Miller M.D.

  2. Department of Diagnostic Imaging, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada

    Elysa Widjaja M.B.B.S., M.R.C.P., F.R.C.R., M.D.

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  1. Elka Miller M.D.
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  2. Elysa Widjaja M.B.B.S., M.R.C.P., F.R.C.R., M.D.
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Correspondence to Elka Miller M.D. .

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  1. Keck School of Medicine, Dept. Radiology, University of Southern California, Zonal Avenue 1975, Los Angeles, 90089-9034, California, USA

    Stefan Blüml

  2. , Dept. of Pediatric Radiology, Children's Hospital of Pittsburg of UPMC, Penn Avenue 4401, Pittsburgh, 15224, Pennsylvania, USA

    Ashok Panigrahy

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Miller, E., Widjaja, E. (2013). Magnetic Resonance Spectroscopy in Epilepsy. In: Blüml, S., Panigrahy, A. (eds) MR Spectroscopy of Pediatric Brain Disorders. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-5864-8_15

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  • DOI: https://doi.org/10.1007/978-1-4419-5864-8_15

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