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Basic Study Design

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Fundamentals of Clinical Trials

Abstract

The foundations for the design of controlled experiments were established for agricultural application. They are described in several classical statistics textbooks [1–4]. From these sources evolved the basic design of controlled clinical trials.

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Authors and Affiliations

  1. Bethesda, MD, USA

    Lawrence M. Friedman

  2. School of Medicine, Wake Forest University, Winston-Salem, NC, USA

    Curt D. Furberg

  3. Department of Biostatistics & Medical Informatics, University of Wisconsin, Madison, WI, USA

    David L. DeMets

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  1. Lawrence M. Friedman
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  2. Curt D. Furberg
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  3. David L. DeMets
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Correspondence to Lawrence M. Friedman .

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Friedman, L.M., Furberg, C.D., DeMets, D.L. (2010). Basic Study Design. In: Fundamentals of Clinical Trials. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1586-3_5

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