Abstract
Molecular diagnostics, the use of diagnostic testing to understand the molecular mechanisms of an individual patient’s disease, will be pivotal in the delivery of safe and effective therapy for many diseases in the future. Role of molecular diagnostics in personalized medicine covers the following aspects: Early detection and selection of appropriate treatment determined to be safe and effective on the basis of molecular diagnostics Integration of molecular diagnostics with therapeutics Monitoring therapy as well as determining prognosis
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Jain KK (2005) Personalised medicine for cancer – from drug development into clinical practice. Exp Opin Pharmacother 6:1463–1476
Jain KK (2007) Applications of nanobiotechnology in clinical diagnostics. Clin Chem 53:2002–2009
Jain KK (2008) A handbook of nanomedicine. Springer/Human Press, Tatowa, NJ.
Jain KK (2009a) Molecular diagnostics: technologies, markets and companies. Jain PharmaBiotech, Basel, Switzerland.
Jain KK (2009b) DNA sequencing: technologies, markets and companies. Jain PharmaBiotech, Basel, Switzerland.
Jain KK (2009c) Biochips/microarrays: technologies, markets and companies. Jain PharmaBiotech, Basel, Switzerland.
Jain KK (2009d) Nanobiotechnology: applications, markets and companies. Jain PharmaBiotech, Basel, Switzerland.
Jain KK (2009e) Proteomics: technologies, markets and companies. Jain PharmaBiotech, Basel, Switzerland.
Jain KK (2009n) Cytogenetics: technologies, markets and companies. Jain PharmaBiotech, Basel, Switzerland.
Lin M, Aquilante C, Johnson JA, Wu R (2005) Sequencing drug response with HapMap. Pharma-cogenomics J 5:149–156
Manolio TA, Brooks LD, Collins FS (2008) A HapMap harvest of insights into the genetics of common disease. J Clin Invest 118:1590–1605
Valet G (2005) Cytomics, the human cytome project and systems biology: top-down reso-lution of the molecular biocomplexity of organisms by single cell analysis. Cell Prolif 38:171–174
Zhang J, Lang HP, Huber F et al (2006) Rapid and label-free nanomechanical detection of biomarker transcripts in human RNA. Nat Nanotechnol 1:214–220
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2009 Springer Science+Business Media, LLC
About this chapter
Cite this chapter
Jain, K.K. (2009). Molecular Diagnostics as Basis of Personalized Medicine. In: Textbook of Personalized Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-0769-1_2
Download citation
DOI: https://doi.org/10.1007/978-1-4419-0769-1_2
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4419-0768-4
Online ISBN: 978-1-4419-0769-1
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)