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Calcium Pyrophosphate Dihydrate, Hydroxyapatite, and Miscellaneous Crystals

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Primer on the Rheumatic Diseases

Abstract

Calcium pyrophosphate dihydrate (CPPD) and hydro-xyapatite crystals are the most common calcium-containing crystals associated with joint and periarticular disorders. Deposition of these crystals is frequently asymptomatic or can be intermittently symptomatic. However, common clinical manifestations of calcium crystal deposition include acute or chronic inflammatory and degenerative arthritides, and certain forms of periarthritis. In addition to these, a number of other crystalline materials have been identified less commonly in synovial or bursal fluid. These include calcium oxalate, cholesterol, lipids, and synthetic corticosteroid crystals.

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Author information

Authors and Affiliations

  1. Division of Rheumatology, Department of Medicine, University College Dublin, Dublin/Mater Misericordiae University Hospital, Dublin, Ireland

    Geraldine McCarthy MD, FRCPI (Associate Professor/Consultant Rheumatologist)

Authors
  1. Geraldine McCarthy MD, FRCPI
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Editor information

Editors and Affiliations

  1. Arthritis Foundation, Atlanta, GA, USA

    John H. Klippel MD (President and CEO) (President and CEO)

  2. Massachusetts General Hospital, Boston, MA, USA

    John H. Stone MD, MPH (Associate Physician, Deputy Editor for Rheumatology) (Associate Physician, Deputy Editor for Rheumatology)

  3. Division of Rheumatology & Women’s Health, University of Kentucky, Lexington, KY, USA

    Leslie J. Crofford MD (Gloria W. Singletary Professor of Internal Medicine, Chief) (Gloria W. Singletary Professor of Internal Medicine, Chief)

  4. Arthritis Foundation, Atlanta, GA, USA

    Patience H. White MD, MA (Chief Public Health Officer) (Chief Public Health Officer)

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© 2008 Springer Science+Business Media, LLC

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McCarthy, G. (2008). Calcium Pyrophosphate Dihydrate, Hydroxyapatite, and Miscellaneous Crystals. In: Klippel, J.H., Stone, J.H., Crofford, L.J., White, P.H. (eds) Primer on the Rheumatic Diseases. Springer, New York, NY. https://doi.org/10.1007/978-0-387-68566-3_13

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  • DOI: https://doi.org/10.1007/978-0-387-68566-3_13

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-35664-8

  • Online ISBN: 978-0-387-68566-3

  • eBook Packages: MedicineMedicine (R0)

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