Abstract
Osteoarthritis (OA) is the most common form of joint disease in humans. Our ancestors’ skeletons show that it has been with us for many centuries. However, it was only differentiated from other forms of arthritis about 100 years ago (1), when a combination of pathological and radiographic studies made it clear that there were two quite distinct types of synovial joint damage: atrophic arthritis, in which there is periarticular osteoporosis and erosive changes, in addition to cartilage loss; and hypertrophic arthritis, in which the cartilage loss is accompanied by an increase in bone density and bone formation around the joint.
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Dieppe, P. (2008). Osteoarthritis. In: Klippel, J.H., Stone, J.H., Crofford, L.J., White, P.H. (eds) Primer on the Rheumatic Diseases. Springer, New York, NY. https://doi.org/10.1007/978-0-387-68566-3_11
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DOI: https://doi.org/10.1007/978-0-387-68566-3_11
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